Tdark COX7B2 Cytochrome c oxidase subunit 7B2, mitochondrial

Protein Summary

Description

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Uniprot Accession IDs

• Q8TF08
• Q32Q40

Gene Name

• COX7B2

Ensembl ID

• ENST00000355591
• ENSP00000347799
• ENSG00000170516
• ENST00000396533
• ENSP00000379784

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.6
molecular function	0.6
phenotype	0.48
metabolite	0.45
disease	0.42

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.04   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 38   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.04   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0