ST7L
Suppressor of tumorigenicity 7 protein-like
Protein Summary
This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]
- ENST00000343210
- ENSP00000345312
- ENSG00000007341
- ENST00000358039
- ENSP00000350734
- ENST00000360743
- ENSP00000353972
- ENST00000361846
- ENSP00000436499
- ENST00000369666
- ENSP00000358680
- ENST00000369669
- ENSP00000358683
- ENST00000490067
- ENSP00000417140
- ENST00000490715
- ENSP00000436544
- ST7R
- ST7R
- STLR
- FAM4B
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.87 | ||
transcription factor binding site profile | 0.74 | ||
transcription factor perturbation | 0.74 | ||
cell type or tissue | 0.69 | ||
microRNA | 0.63 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 38.79 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 32 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 38.79 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 32 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0