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Tbio Rhophilin-1

Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules (By similarity).

 Comments

Property Summary

NCBI Gene PubMed Count 9
PubMed Score 6.03
PubTator Score 3.34

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (4)

Disease Target Count Z-score Confidence
Polycystic ovary syndrome 360 0.0 0.0
Disease Target Count P-value
lung adenocarcinoma 2716 1.9e-06
ovarian cancer 8520 1.2e-04
breast carcinoma 1638 6.1e-04
inflammatory breast cancer 286 1.8e-02
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.5
Disease Target Count Z-score Confidence
Opisthorchiasis 15 4.131 2.1

Expression

  Differential Expression (4)

Disease log2 FC p
breast carcinoma 1.200 6.1e-04
inflammatory breast cancer 1.100 1.8e-02
lung adenocarcinoma 1.500 1.9e-06
ovarian cancer -1.200 1.2e-04

Synonym

Accession Q8TCX5 Q8TAV1 Q96PV9
Symbols ODF5
RHPN
RHOPHILIN

Gene

RHPN1

PANTHER Protein Class (2)

  Ortholog (14)

Species Source Disease
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA
Inparanoid OMA EggNOG
Inparanoid EggNOG
Inparanoid OMA EggNOG

 UniProt Keyword (4)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (10)

 IMPC Phenotype (2)

 MGI Phenotype (1)

 GWAS Trait (1)

 HCA RNA Cell Line (46)

See all...

Pathway (5)

Protein-protein Interaction (29)

MELK   USP15   GOLGA2   USP47   SNTB2   PTPN21   PTPN14   MCMBP   KLHL11   PPP4R3A   UTRN   TTC19   NDUFB9   GORASP1   DTNB   PODXL   SPAG5   MAPK9   PREP   PODXL2   IFT81   ZBTB10   MTMR4   IFT74   WWC1   WDR47   WWC2   CTNNAL1   LZTS2  

Gene RIF (1)

AA Sequence 

MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETV      1 - 70
ALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGAS     71 - 140
YEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALA    141 - 210
FEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLM    211 - 280
MAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEY    281 - 350
FRSLAHYHVAMALCDGSRECPPHLPMVLPRPPRAGSQPLCPPAATEGELPTHEQVFLQPPTSSKPRGPVL    351 - 420
PQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAE    421 - 490
APDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLI    491 - 560
AAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPV    561 - 630
LLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP         631 - 695
//

Text Mined References (9)

PMID Year Title