Property Summary

NCBI Gene PubMed Count 15
PubMed Score 2.41
PubTator Score 31.31

Knowledge Summary

Patent (989)

Expression

  Differential Expression (13)

Disease log2 FC p
astrocytic glioma -1.800 0.003
ependymoma -1.800 0.011
oligodendroglioma -1.500 0.019
psoriasis -2.500 0.000
osteosarcoma -1.281 0.009
atypical teratoid / rhabdoid tumor -1.500 0.000
glioblastoma -1.300 0.000
medulloblastoma -1.400 0.000
medulloblastoma, large-cell -1.900 0.000
primitive neuroectodermal tumor -1.100 0.004
intraductal papillary-mucinous neoplasm ... 1.400 0.000
invasive ductal carcinoma 1.100 0.003
pituitary cancer 1.200 0.000

Synonym

Accession Q8TBX8 B2RDL3 B4DM11 B4DY44 Q9H6N2
Symbols PIP5K2C

Gene

PANTHER Protein Class (2)

PDB

2GK9  

  TechDev Info (1)

Gary Johnson Kinome profile via MIB/MS Technology

 Collection (1)

Gene RIF (3)

PMID Text
20439292 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19644859 Observational study of gene-disease association. (HuGE Navigator)
18794853 Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator)

AA Sequence

MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM      1 - 70
LLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEGSDGR     71 - 140
FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHR    141 - 210
LPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMD    211 - 280
YSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESF    281 - 350
IDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF    351 - 420
A//

Text Mined References (21)

PMID Year Title
25578879 2015 PI(5)P regulates autophagosome biogenesis.
25495341 2015 The function of phosphatidylinositol 5-phosphate 4-kinase ? (PI5P4K?) explored using a specific inhibitor that targets the PI5P-binding site.
23758345 2013 Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization.
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
21269460 2011 Initial characterization of the human central proteome.
20439292 2010 Genetic variants in the prediction of rheumatoid arthritis.
19644859 2009 Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
19056867 2009 Large-scale proteomics and phosphoproteomics of urinary exosomes.
18794853 2008 Common variants at CD40 and other loci confer risk of rheumatoid arthritis.
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