Tbio CMTM2 CKLF-like MARVEL transmembrane domain-containing protein 2

Protein Summary

Description

This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q8TAZ6
• Q5I2A4
• Q8N7E5

Gene Name

• CMTM2

Ensembl ID

• ENST00000268595
• ENSP00000268595
• ENSG00000140932
• ENST00000379486
• ENSP00000368800

Symbol

• CKLFSF2
• CKLFSF2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.71
cell type or tissue	0.66
cell line	0.56
gene perturbation	0.53
tissue	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.04   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 141   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.04   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 141   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0