| Tbio | Stomatin-like protein 3 |
Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6694 | 4.3e-19 |
| nasopharyngeal carcinoma | 1058 | 8.7e-06 |
| ependymoma | 4679 | 3.5e-03 |
| chronic rhinosinusitis | 512 | 2.4e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Metabolic syndrome X | 52 | 0.0 | 1.2 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Syndromic X-linked intellectual disability Snyder type | 21 | 3.122 | 1.6 |
| gliosarcoma | 18 | 3.036 | 1.5 |
| Disease | log2 FC | p |
|---|---|---|
| chronic rhinosinusitis | -2.100 | 2.4e-02 |
| ependymoma | 1.500 | 3.5e-03 |
| nasopharyngeal carcinoma | -1.500 | 8.7e-06 |
| psoriasis | -2.200 | 4.3e-19 |
MDSRVSSPEKQDKENFVGVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQA 1 - 70 DKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQAT 71 - 140 FLLAQTTLRNVLGTQTLSQILAGREEIAHSIQTLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEA 141 - 210 TREARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQTLSTVATEKNSTIVFPLPMNILEGIGGVS 211 - 280 YDNHKKLPNKA 281 - 291 //
