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Tbio
STOML3
Stomatin-like protein 3

Protein Summary
Description
Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000379631
  • ENSP00000368952
  • ENSG00000133115
  • ENST00000423210
  • ENSP00000401989

Symbol
  • SRO
  • Epb7.2l
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.58
gene perturbation
0.56
microRNA
0.56
virus perturbation
0.55
cell type or tissue
0.51


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.9   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 90   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.9   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0