Protein Summary
Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).
- ENST00000302541
- ENSP00000301972
- ENSG00000170011
- ENST00000396217
- ENSP00000379519
- ENST00000425621
- ENSP00000389323
- ENST00000444716
- ENSP00000398665
- ENST00000458292
- ENSP00000413392
- ENST00000539167
- ENSP00000438297
- SLAC2C
- SLAC2C
- SLAC2-C
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
trait | 0.93 | ||
kinase perturbation | 0.81 | ||
microRNA | 0.71 | ||
PubMedID | 0.71 | ||
histone modification site profile | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.62 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 158 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.62 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 158 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0