| Tdark | C2 calcium-dependent domain-containing protein 4A |
May be involved in inflammatory process. May regulate cell architecture and adhesion.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Diabetes Mellitus, Type 2 | 142 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Diabetes Mellitus, Non-Insulin-Dependent | 145 |
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6694 | 2.6e-19 |
| non-small cell lung cancer | 2890 | 1.8e-07 |
| head and neck cancer | 271 | 2.7e-06 |
| pituitary cancer | 1972 | 3.7e-06 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 4.3e-04 |
| Breast cancer | 3578 | 3.7e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 4.4e-03 |
| active ulcerative colitis | 764 | 4.5e-03 |
| active Crohn's disease | 922 | 7.0e-03 |
| Endometriosis | 540 | 1.7e-02 |
| ductal carcinoma in situ | 1745 | 2.5e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Acquired metabolic disease | 336 | 0.0 | 3.0 |
| Type 2 diabetes mellitus | 272 | 0.0 | 3.0 |
| Disease | log2 FC | p |
|---|---|---|
| active Crohn's disease | 4.110 | 7.0e-03 |
| active ulcerative colitis | 3.693 | 4.5e-03 |
| Breast cancer | 1.500 | 3.7e-03 |
| ductal carcinoma in situ | 1.500 | 2.5e-02 |
| Endometriosis | -2.284 | 1.7e-02 |
| head and neck cancer | 1.600 | 2.7e-06 |
| intraductal papillary-mucinous carcinoma... | 3.500 | 4.3e-04 |
| intraductal papillary-mucinous neoplasm ... | 2.800 | 4.4e-03 |
| non-small cell lung cancer | 1.271 | 1.8e-07 |
| pituitary cancer | -3.700 | 3.7e-06 |
| psoriasis | 1.500 | 2.6e-19 |
| Accession | Q8NCU7 |
| Symbols |
NLF1 FAM148A |
MWCLERLRLGPECLRRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRLMPRLALAALRNSWVE 1 - 70 EAGMDEGAGRTDWDPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESLLLGGPPAPRPRAHTYGGGGG 71 - 140 PDALLGTLRVPRAPGPATPAAPGCPRPPQDALARRPRGCRLLRVPDGLLSRALRAGRSRRLTRVRSVSSG 141 - 210 NEDKERRAGSQSPARAPSTSPPSSRVPFPERLEAEGTVALGRAGDALRLAAEYCPGTGRLRLRLLRAESP 211 - 280 AGGAPGPRAVSCRLSLVLRPPGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGR 281 - 350 ERGRLLGQGELSLGALLLL 351 - 369 //
