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Tbio
SERBP1
Plasminogen activator inhibitor 1 RNA-binding protein

Protein Summary
Description
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361219
  • ENSP00000354591
  • ENSG00000142864
  • ENST00000370990
  • ENSP00000360029
  • ENST00000370994
  • ENSP00000360033
  • ENST00000370995
  • ENSP00000360034

Symbol
  • PAIRBP1
  • CGI-55
  • CHD3IP
  • HABP4L
  • PAIRBP1
  • PAI-RBP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
kinase perturbation
1
disease perturbation
0.99
transcription factor perturbation
0.98
microRNA
0.96


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.9   (req: < 5)
Gene RIFs: 29   (req: <= 3)
Antibodies: 309   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.9   (req: >= 5)
Gene RIFs: 29   (req: > 3)
Antibodies: 309   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0