Property Summary

NCBI Gene PubMed Count 10
Grant Count 6
Funding $673,016.44
PubMed Score 4.64
PubTator Score 3.14

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (5)

Disease log2 FC p
pancreatic ductal adenocarcinoma liver m... 2.106 0.030
pancreatic cancer 1.100 0.001
interstitial cystitis -2.500 0.000
psoriasis -3.200 0.000
inflammatory breast cancer -1.700 0.001

Gene RIF (4)

PMID Text
21336277 Inactivation of the insulin promoter by promoter-targeting siRNA reduces SYT8 gene expression.
20628086 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19913121 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGVLLVSCLLCAA      1 - 70
CCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGCLQLSLEFDFGSQEIRVGLRQ     71 - 140
AADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH    141 - 210
EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPY    211 - 280
VKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGAR    281 - 350
ASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS                       351 - 401
//

Text Mined References (12)

PMID Year Title
24065953 2013 The functional significance of synaptotagmin diversity in neuroendocrine secretion.
23936387 2013 A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.
22928559 2012 Chromatin structure, epigenetic mechanisms and long-range interactions in the human insulin locus.
21336277 2011 Mapping of INS promoter interactions reveals its role in long-range regulation of SYT8 transcription.
20628086 2010 Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19913121 2009 Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16554811 2006 Human chromosome 11 DNA sequence and analysis including novel gene identification.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
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