Property Summary

NCBI Gene PubMed Count 11
PubMed Score 1.29
PubTator Score 3.56

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
psoriasis 6685 1.55957617109888E-30
lung carcinoma 2844 3.91868420132944E-29
osteosarcoma 7933 1.19741963977745E-6
posterior fossa group B ependymoma 1530 1.31337252172951E-6
pancreatic ductal adenocarcinoma liver metastasis 1795 0.00166797322709635
pituitary cancer 1972 0.00293990520604082
sonic hedgehog group medulloblastoma 1482 0.00782980382112309
active Crohn's disease 918 0.0159536586173892
active ulcerative colitis 477 0.019128575341493
acute myeloid leukemia 785 0.0216338123196836
ductal carcinoma in situ 1745 0.0365689011828679
Disease Target Count Z-score Confidence
Von Willebrand's disease 19 3.188 1.6

Expression

  Differential Expression (11)

Synonym

Accession Q8N9U0
Symbols C2CD1
Tac2-N
MTAC2D1
C14orf47

Gene

  Ortholog (13)

Gene RIF (2)

PMID Text
24667918 Microarray analysis indicates HIV-1 Tat-induced upregulation of tandem C2 domains, nuclear (TC2N) in primary human brain microvascular endothelial cells
21029358 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDG      1 - 70
KEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDL     71 - 140
SRRFPPRSEVKRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNR    141 - 210
SLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSA    211 - 280
KEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISV    281 - 350
CHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWG    351 - 420
ETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS    421 - 490
//

Text Mined References (14)

PMID Year Title
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
21810271 2011 Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.
21029358 2011 Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.
18088087 2008 Phosphoproteome of resting human platelets.
16381901 2006 The LIFEdb database in 2006.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489336 2004 From ORFeome to biology: a functional genomics pipeline.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12508121 2003 The DNA sequence and analysis of human chromosome 14.
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