Tbio FTMT Ferritin, mitochondrial

Protein Summary

Description

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Uniprot Accession IDs

• Q8N4E7

Gene Name

• FTMT

Ensembl ID

• ENST00000321339
• ENSP00000313691
• ENSG00000181867

Symbol

• MTF

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.85
cell line	0.78
biological term	0.54
cell type or tissue	0.5
tissue	0.48

Protein Classes

PANTHER Classes

Protein / Storage Protein / Ferritin, Mitochondrial

DTO Classes

Protein / Storage / Ferritin, Mitochondrial

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.41   (req: < 5)

Gene RIFs: 36   (req: <= 3)

Antibodies: 62   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.41   (req: >= 5)

Gene RIFs: 36   (req: > 3)

Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0