| Tdark | Protein FAM19A2 |
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| glioblastoma | 5792 | 8.9e-07 |
| pituitary cancer | 1972 | 6.3e-06 |
| atypical teratoid / rhabdoid tumor | 5112 | 5.0e-05 |
| adult high grade glioma | 3801 | 3.3e-04 |
| osteosarcoma | 7950 | 4.2e-04 |
| interstitial cystitis | 2312 | 7.7e-04 |
| astrocytic glioma | 2597 | 1.2e-03 |
| primitive neuroectodermal tumor | 3035 | 1.8e-03 |
| Astrocytoma, Pilocytic | 3081 | 1.9e-03 |
| medulloblastoma, large-cell | 6241 | 2.2e-03 |
| medulloblastoma | 720 | 3.7e-03 |
| ependymoma | 4679 | 6.0e-03 |
| oligodendroglioma | 2850 | 4.8e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Cornelia de Lange syndrome | 21 | 3.793 | 1.9 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -3.400 | 3.3e-04 |
| astrocytic glioma | -2.700 | 1.2e-03 |
| Astrocytoma, Pilocytic | -1.900 | 1.9e-03 |
| atypical teratoid / rhabdoid tumor | -3.100 | 5.0e-05 |
| ependymoma | -3.100 | 6.0e-03 |
| glioblastoma | -2.900 | 8.9e-07 |
| interstitial cystitis | -2.600 | 7.7e-04 |
| medulloblastoma | -2.000 | 3.7e-03 |
| medulloblastoma, large-cell | -3.600 | 2.2e-03 |
| oligodendroglioma | -1.400 | 4.8e-02 |
| osteosarcoma | -2.204 | 4.2e-04 |
| pituitary cancer | -2.300 | 6.3e-06 |
| primitive neuroectodermal tumor | -2.800 | 1.8e-03 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA |
