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Tbio
ELMOD1
ELMO domain-containing protein 1

Protein Summary
Description
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265840
  • ENSP00000265840
  • ENSG00000110675
  • ENST00000443271
  • ENSP00000412257
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.96
histone modification site profile
0.7
microRNA
0.65
tissue sample
0.64
transcription factor perturbation
0.54


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.32   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.32   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0