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Tbio
STK40
Serine/threonine-protein kinase 40

Protein Summary
Description
May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359297
  • ENSP00000352245
  • ENSG00000196182
  • ENST00000373129
  • ENSP00000362221
  • ENST00000373130
  • ENSP00000362222
  • ENST00000373132
  • ENSP00000362224

Symbol
  • SGK495
  • SHIK
  • SHIK
  • SgK495
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.97
molecular function
0.91
disease perturbation
0.83
transcription factor
0.82
microRNA
0.81


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.85   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 150   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.85   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 150   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0