Tbio SLC39A11 Zinc transporter ZIP11

Protein Summary

Description

Functions as a cellular zinc transporter.

Uniprot Accession IDs

• Q8N1S5
• B2R8H7
• Q8WZ81

Gene Name

• SLC39A11

Ensembl ID

• ENST00000255559
• ENSP00000255559
• ENSG00000133195
• ENST00000542342
• ENSP00000445829
• ENST00000642526
• ENSP00000496413
• ENSG00000285189
• ENST00000645633
• ENSP00000494287

Symbol

• C17orf26
• ZIP11
• ZIP11
• ZIP-11
• C17orf26

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.85
phenotype	0.8
histone modification site profile	0.78
transcription factor binding site profile	0.78
disease perturbation	0.74

Protein Classes

PANTHER Classes

Protein / Transmembrane Receptor Regulatory/adaptor Protein / Zinc Transporter Zip11

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc39 Family Of Metal Ion Transporters / Zinc Transporter Zip11

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.34   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 109   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.34   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0