Tclin CA13 Carbonic anhydrase 13

Protein Summary

Description

Reversible hydration of carbon dioxide. Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. For background information on the CA family, see MIM 114800.[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q8N1Q1

Gene Name

• CA13

Ensembl ID

• ENST00000321764
• ENSP00000318912
• ENSG00000185015

Symbol

• CAXIII

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.97
histone modification site profile	0.89
transcription factor perturbation	0.74
microRNA	0.64
PubMedID	0.6

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 105.89   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 180   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 105.89   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 180   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 274

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 10