Tdark FAM177A1 Protein FAM177A1

Protein Summary

Description

This gene encodes a member of a conserved protein family. Alternative splicing results in multiple transcript variants. This gene is thought to be associated with susceptibility to juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]

Uniprot Accession IDs

• Q8N128
• Q68CT2

Gene Name

• FAM177A1

Ensembl ID

• ENST00000280987
• ENSP00000280987
• ENSG00000151327
• ENST00000382406
• ENSP00000371843
• ENST00000396472
• ENSP00000379734

Symbol

• C14orf24
• C14orf24

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.84
microRNA	0.62
tissue sample	0.62
cell line	0.53
tissue	0.46

Protein Classes

PANTHER Classes

Protein / Transferase / Glycosyltransferase / Protein Fam177a1

DTO Classes

Protein / Enzyme / Transferase / Glycosyltransferase / Protein Fam177a1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.67   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 39   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.67   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 39   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0