Tbio CEND1 Cell cycle exit and neuronal differentiation protein 1

Protein Summary

Description

Involved in neuronal differentiation. The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q8N111
• Q9NYM6

Gene Name

• CEND1

Ensembl ID

• ENST00000330106
• ENSP00000328336
• ENSG00000184524

Symbol

• BM88
• BM88

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.65
cell type or tissue	0.62
tissue	0.54
transcription factor	0.5
small molecule perturbation	0.48

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.45   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 101   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.45   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0