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Tbio
RAVER1
Ribonucleoprotein PTB-binding 1

Protein Summary
Description
Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000615032
  • ENSP00000479520
  • ENSG00000161847

Symbol
  • KIAA1978
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein complex
1
interacting protein
0.96
ligand (protein) perturbation
0.96
histone modification site profile
0.89
transcription factor binding site profile
0.79


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 108   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 108   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0