| Tbio | Nurim |
The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Toxic megacolon | 6 | 4.594 | 2.3 |
| Paralytic ileus | 5 | 4.25 | 2.1 |
| Intestinal pseudo-obstruction | 12 | 3.82 | 1.9 |
MAPALLLIPAALASFILAFGTGVEFVRFTSLRPLLGGIPESGGPDARQGWLAALQDRSILAPLAWDLGLL 1 - 70 LLFVGQHSLMAAERVKAWTSRYFGVLQRSLYVACTALALQLVMRYWEPIPKGPVLWEARAEPWATWVPLL 71 - 140 CFVLHVISWLLIFSILLVFDYAELMGLKQVYYHVLGLGEPLALKSPRALRLFSHLRHPVCVELLTVLWVV 141 - 210 PTLGTDRLLLAFLLTLYLGLAHGLDQQDLRYLRAQLQRKLHLLSRPQDGEAE 211 - 262 //
