Property Summary

NCBI Gene PubMed Count 10
Grant Count 11
R01 Count 11
Funding $1,031,483.56
PubMed Score 14.70
PubTator Score 9.02

Knowledge Summary

Patent

No data available

Expression

 GO Function (1)

Gene RIF (5)

PMID Text
26088750 SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
25038051 The levels of antibodies reactive with SPRASA were elevated in infertile women.
24872021 Authors present evidence that the variants could affect the expression levels or function of SPRASA, thereby affecting a couple's fertility.
15475442 SLLP1 is capable of eliciting B-cell immune responses in vivo in cancer-bearing individuals.
12606493 SLLP1 could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane

AA Sequence

MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSAAGIEARSRALRRRWCPAGIM      1 - 70
LLALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNAAALDYEADGSTNN     71 - 140
GIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWV    141 - 210
DGCDF                                                                     211 - 215
//

Text Mined References (11)

PMID Year Title
26088750 2015 Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
25038051 2015 The role of SPRASA in female fertility.
24872021 2014 SPACA3 gene variants in a New Zealand cohort of infertile and fertile couples.
19945174 2010 Identification of human sperm proteins that interact with human zona pellucida3 (ZP3) using yeast two-hybrid system.
16014814 2005 Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15475442 2004 The spermatozoa protein, SLLP1, is a novel cancer-testis antigen in hematologic malignancies.
14747161 2004 SPRASA, a novel sperm protein involved in immune-mediated infertility.
12975309 2003 The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
12606493 2003 SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa.
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