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Tdark
DHX40
Probable ATP-dependent RNA helicase DHX40

Protein Summary
Description
Probable ATP-dependent RNA helicase. This gene encodes a member of the DExH/D box family of ATP-dependent RNA helicases that have an essential role in RNA metabolism. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Oct 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000251241
  • ENSP00000251241
  • ENSG00000108406
  • ENST00000425628
  • ENSP00000388749

Symbol
  • DDX40
  • PAD
  • DDX40
  • ARG147
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.99
kinase perturbation
0.98
protein domain
0.92
histone modification site profile
0.91
transcription factor
0.82


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.37   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.37   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0