Tbio ZC3H7A Zinc finger CCCH domain-containing protein 7A

Protein Summary

Description

May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3'-ATA(A/T)-5' motif in the apical loop.

Uniprot Accession IDs

• Q8IWR0
• D3DUG5
• Q9NPE9

Gene Name

• ZC3H7A

Ensembl ID

• ENST00000355758
• ENSP00000347999
• ENSG00000122299
• ENST00000396516
• ENSP00000379773
• ENST00000575984
• ENSP00000459477

Symbol

• ZC3H7
• ZC3HDC7
• ZC3H7
• HSPC055
• ZC3HDC7

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.94
transcription factor binding site profile	0.92
virus perturbation	0.88
histone modification site profile	0.67
tissue sample	0.58

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Zinc Finger Ccch Domain-containing Protein 7a

DTO Classes

Protein / Nucleic Acid Binding / Zinc Finger Ccch Domain-containing Protein 7a

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.07   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 119   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.07   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0