Protein Summary
Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
- ENST00000341228
- ENSP00000342109
- ENSG00000165953
- ENST00000556881
- ENSP00000451738
- OL-64
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.78 | ||
biological term | 0.68 | ||
biological process | 0.54 | ||
cell line | 0.53 | ||
protein complex | 0.48 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 266.85 (req: < 5)
Gene RIFs: 140 (req: <= 3)
Antibodies: 336 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 266.85 (req: >= 5)
Gene RIFs: 140 (req: > 3)
Antibodies: 336 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0