Tdark VSTM4 V-set and transmembrane domain-containing protein 4

Protein Summary

Description

Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors.

Uniprot Accession IDs

• Q8IW00
• B4DNI6
• Q96MX7

Gene Name

• VSTM4

Ensembl ID

• ENST00000298454
• ENSP00000298454
• ENSG00000165633
• ENST00000332853
• ENSP00000331062

Symbol

• C10orf72
• C10orf72

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.81
transcription factor perturbation	0.74
protein domain	0.58
co-expressed gene	0.57
cell type or tissue	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.44   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 57   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.44   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0