Property Summary

NCBI Gene PubMed Count 8
Grant Count 40
R01 Count 29
Funding $4,257,504.01
PubMed Score 15.84
PubTator Score 39.23

Knowledge Summary


No data available


  Differential Expression (10)

Disease log2 FC p
ependymoma -1.300 0.000
glioblastoma -1.300 0.000
group 4 medulloblastoma -1.400 0.048
atypical teratoid/rhabdoid tumor -1.400 0.003
fibroadenoma 1.400 0.003
adult high grade glioma -1.700 0.017
pilocytic astrocytoma -1.200 0.029
subependymal giant cell astrocytoma -2.319 0.016
inflammatory breast cancer -1.400 0.022
psoriasis -1.100 0.000

Gene RIF (2)

18768681 characterization of the mouse 136 aa conserved isoform, Ret-PCP2
16298104 The data demonstrate that PCP-2 is a comparatively weak GoLoco motif protein that exhibits highest affinity interactions and GDI activity toward Galphai1, Galphai2, and Galphai3 subunits.

AA Sequence


Text Mined References (9)

PMID Year Title
18768681 2008 Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response.
17215137 2007 A promoter element with enhancer properties, and the orphan nuclear receptor RORalpha, are required for Purkinje cell-specific expression of a Gi/o modulator.
16298104 2006 G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of the dual GoLoco motif protein PCP-2 (Purkinje cell protein-2).
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15057824 2004 The DNA sequence and biology of human chromosome 19.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12399102 2002 Conservation of the developmentally regulated dendritic localization of a Purkinje cell-specific mRNA that encodes a G-protein modulator: comparison of rodent and human Pcp2(L7) gene structure and expression.
10196137 1999 Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor.