Property Summary

NCBI Gene PubMed Count 16
Grant Count 1
Funding $14,848
PubMed Score 35.89
PubTator Score 3.00

Knowledge Summary

Patent

No data available

Expression

Synonym

Accession Q86YS6 A8K4P9 E9PBQ0
Symbols RAB41
RAB11B

Gene

 Grant Application (1)

PDB

2HUP  

Gene RIF (8)

PMID Text
24248336 several crystal structures of the myosin Va or the myosin Vb globular tail domain that gives insights into how the motor is linked to the recycling membrane compartments via Rab11 or the melanophilin adaptor that binds to Rab27a.
23615442 Data indicate taht the parasitophorous vacuole (PV), marked with Rab14, Rab30, or Rab43, colocalize with host-derived sphingolipids in the vacuolar space.
23589291 SGK1,3 enhances the expression level of mature hERG channels by inhibiting Nedd4-2 as well as by promoting Rab11-mediated hERG recycling.
21680502 Rab1a/b and Rab43, are important for herpes simplex virus 1 virion assembly
18664496 Rab18 and Rab43 have key roles in ER-Golgi trafficking.
17684057 Results indicate that Rab1 and Rab43 are key Rabs required for the biogenesis and maintenance of a functional Golgi structure, and suggest that other Rabs acting at the Golgi complex are likely to be functionally redundant.
17562788 Rab43 is the target of RN-tre and is required for Shiga toxin uptake.
15018353 The results of PCR amplification indicated that human RAB41 is widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver.

AA Sequence

MAGPGPGPGDPDEQYDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQ      1 - 70
IWDTAGQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELRE     71 - 140
VSLAEAQSLAEHYDILCAIETSAKDSSNVEEAFLRVATELIMRHGGPLFSEKSPDHIQLNSKDIGEGWGC    141 - 210
GC                                                                        211 - 212
//

Text Mined References (21)

PMID Year Title
25277244 2014 The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.
24891604 2014 Rab18 and a Rab18 GEF complex are required for normal ER structure.
24248336 2013 Structural basis of myosin V Rab GTPase-dependent cargo recognition.
23615442 2013 Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.
23589291 2013 The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11.
21680502 2011 Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment.
21269460 2011 Initial characterization of the human central proteome.
21255211 2011 Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19056867 2009 Large-scale proteomics and phosphoproteomics of urinary exosomes.
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