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Tdark Coiled-coil domain-containing protein 25


 Comments

Property Summary

NCBI Gene PubMed Count 9
PubMed Score 0.83
PubTator Score 0.37

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
group 4 medulloblastoma 1875 2.5283855905196E-8
osteosarcoma 7933 4.90075691301448E-5
psoriasis 6685 5.20122565376808E-5
ovarian cancer 8492 5.21225906012174E-4
pancreatic ductal adenocarcinoma liver metastasis 1795 0.020197458545167

Expression

  Differential Expression (5)

Disease log2 FC p
psoriasis -2.000 0.000
osteosarcoma -1.067 0.000
group 4 medulloblastoma -1.600 0.000
pancreatic ductal adenocarcinoma liver m... -1.166 0.020
ovarian cancer 1.200 0.001

Synonym

Accession Q86WR0 Q0P663 Q96SI2 Q9NV98
Symbols

Gene

CCDC25

  Ortholog (13)

Species Source
Chimp OMA EggNOG
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog OMA EggNOG
Dog OMA Inparanoid
Cow OMA EggNOG Inparanoid
Pig OMA EggNOG Inparanoid
Opossum EggNOG Inparanoid
Platypus OMA EggNOG
Chicken OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
C. elegans OMA EggNOG
S.cerevisiae OMA EggNOG Inparanoid

 GO Component (1)

 Compartment GO Term (13)

 HCA RNA Cell Line (56)

See all...

Pathway (2)

 UniProt Keyword (6)

Gene RIF (1)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence 

MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMD      1 - 70
CAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVER     71 - 140
FPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQDGNDSDEFM      141 - 208
//

Text Mined References (18)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
21269460 2011 Initial characterization of the human central proteome.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19608861 2009 Lysine acetylation targets protein complexes and co-regulates major cellular functions.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
More...