Coiled-coil domain-containing protein 25

Property Summary

NCBI Gene PubMed Count	9
PubMed Score	1.44

PubTator Score	0.37

Knowledge Summary

Patent

No data available

TINX Plot

Disease (1)

Expression Atlas

Disease	Target Count	P-value
group 4 medulloblastoma	1855	2.5e-08
osteosarcoma	7950	4.9e-05
psoriasis	6694	5.2e-05
ovarian cancer	8520	4.4e-04
pancreatic ductal adenocarcinoma liver metastasis	1962	2.0e-02

Differential Expression (5)

Disease	log2 FC	p
group 4 medulloblastoma	-1.600	2.5e-08
osteosarcoma	-1.067	4.9e-05
ovarian cancer	-1.100	4.4e-04
pancreatic ductal adenocarcinoma liver m...	-1.166	2.0e-02
psoriasis	-2.000	5.2e-05

Cells - EBV-transformed lymphocytes 18,186

Cells - Transformed fibroblasts 17,577

Uterus 17,618

Nerve - Tibial 18,007

Brain - Frontal Cortex (BA9) 18,069

Brain - Spinal cord (cervical c-1) 17,973

Brain - Cerebellar Hemisphere 18,015

Small Intestine - Terminal Ileum 17,954

Thyroid 18,024

Artery - Tibial 17,631

Artery - Coronary 17,949

Artery - Aorta 17,896

Testis 18,518

Brain - Cortex 18,039

Adipose - Subcutaneous 18,110

Ovary 17,971

Brain - Substantia nigra 17,981

Brain - Cerebellum 17,983

Brain - Hypothalamus 18,169

Breast - Mammary Tissue 18,103

Adipose - Visceral (Omentum) 17,937

Colon - Sigmoid 18,089

Brain - Nucleus accumbens (basal ganglia... 18,024

Vagina 17,834

Brain - Anterior cingulate cortex (BA24) 17,989

Skin - Sun Exposed (Lower leg) 17,968

Adrenal Gland 18,071

Brain - Amygdala 18,006

Prostate 18,213

Spleen 17,614

Brain - Hippocampus 18,011

Pituitary 18,147

Esophagus - Muscularis 18,017

Esophagus - Gastroesophageal Junction 18,000

Brain - Caudate (basal ganglia) 18,001

Skin - Not Sun Exposed (Suprapubic) 18,081

Minor Salivary Gland 18,005

Brain - Putamen (basal ganglia) 17,863

Stomach 17,879

Muscle - Skeletal 17,778

Esophagus - Mucosa 18,076

Lung 18,057

Colon - Transverse 17,825

Kidney - Cortex 17,329

Heart - Atrial Appendage 17,896

Liver 18,071

Pancreas 18,123

Heart - Left Ventricle 18,006

Whole Blood 17,439

CD8 Cells 9,840

Adult Pancreas 9,168

CD4 Cells 7,773

Adult Prostate 8,952

Adult Rectum 8,022

Adult Spinal Cord 7,594

Adult Liver 9,113

Adult Urinary Bladder 7,592

Fetal Ovary 9,118

Adult Ovary 10,192

Fetal Liver 8,402

Adult Testis 10,836

NK Cells 8,475

B Cells 9,086

Adult Gallbladder 7,612

Adult Adrenal 8,475

Fetal Gut 8,640

Adult Kidney 6,723

Adult Retina 10,115

Fetal Testis 7,955

Adult Lung 6,663

Monocytes 7,422

Adult Colon 7,915

Platelets 6,131

Fetal Heart 9,228

Adrenal gland

Blood platelet

Colon

Gall bladder

Gut

Heart

Kidney

Liver

Lung

B-lymphocyte

Natural killer cell

Ovary

Pancreas

Prostate gland

Rectum

Retina

Spinal cord

Testis

Urinary bladder

BTO:0004410

BTO:0005453

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

Cervical carcinoma cell 4,944

Teratocarcinoma cell 604

Liver 5,008

Retinoblastoma cell 84

Trachea 525

Uterus 1,493

T-cell chronic lymphocytic leukemia cell 2,346

See source...

Biliary epithelial cell 16

Cholangiocyte 1

See source...

Synonym

Accession	Q86WR0 Q0P663 Q96SI2 Q9NV98
Symbols

Gene

CCDC25

Ortholog (14)

Species	Source	Disease
Chimp 14,140	OMA EggNOG
Mouse 16,570	Inparanoid OMA EggNOG
Rat 15,117	Inparanoid OMA EggNOG
Dog 15,073	Inparanoid OMA
Horse 14,252	Inparanoid OMA EggNOG
Cow 15,320	Inparanoid OMA EggNOG
Pig 10,168	Inparanoid OMA EggNOG
Opossum 12,230	Inparanoid EggNOG
Platypus 5,703	OMA EggNOG
Chicken 7,827	Inparanoid OMA EggNOG
Xenopus 10,468	OMA EggNOG
Zebrafish 9,726	Inparanoid OMA EggNOG
C. elegans 3,179	OMA EggNOG
S.cerevisiae 1,799	Inparanoid OMA EggNOG

UniProt Keyword (6)

Complete proteome 20,231

Reference proteome 20,231

Alternative splicing 10,528

Phosphoprotein 8,216

Acetylation 3,409

Coiled coil 2,153

GO Component (1)

extracellular exosome 2,767

Compartment GO Term (3)

Cytosol 6,686

Golgi apparatus 1,933

Nucleoplasm 5,077

GWAS Trait (1)

Chronic sinus infection 39

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Gene RIF (1)

AA Sequence

MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMD      1 - 70
CAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVER     71 - 140
FPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQDGNDSDEFM      141 - 208
//

Text Mined References (18)

Summary
Details

	PMID	Year	Title

Tdark Coiled-coil domain-containing protein 25 Add to cart View Collections Empty Collection