Tdark | Uncharacterized protein C11orf74 |
This gene encodes a protein that was identified as a cellular interacting partner of non-structural protein 10 of the severe acute respiratory syndrome coronavirus (SARS-CoV). The encoded protein may function as a negative regulator of transcription. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Comments
Disease | Target Count | P-value |
---|---|---|
posterior fossa group B ependymoma | 1530 | 4.19939821862964E-6 |
intraductal papillary-mucinous carcinoma (IPMC) | 2988 | 2.6881217181928E-4 |
ovarian cancer | 8492 | 3.17076686808344E-4 |
astrocytic glioma | 2241 | 0.019454999919 |
Disease | log2 FC | p |
---|---|---|
astrocytic glioma | -1.100 | 0.019 |
intraductal papillary-mucinous carcinoma... | -1.300 | 0.000 |
posterior fossa group B ependymoma | 1.200 | 0.000 |
ovarian cancer | -1.100 | 0.000 |
PMID | Year | Title |
---|---|---|
26703212 | 2016 | Search for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient Mice. |
26186194 | 2015 | The BioPlex Network: A Systematic Exploration of the Human Interactome. |
23186163 | 2013 | Toward a comprehensive characterization of a human cancer cell phosphoproteome. |
21478494 | 2011 | Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk. |
19773279 | 2009 | Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. |
18433331 | 2008 | Identification of a novel transcriptional repressor (HEPIS) that interacts with nsp-10 of SARS coronavirus. |
17207965 | 2007 | hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. |
16157265 | 2005 | The interaction of the SARS coronavirus non-structural protein 10 with the cellular oxido-reductase system causes an extensive cytopathic effect. |
15971274 | 2005 | Identification of a third evolutionarily conserved gene within the RAG locus and its RAG1-dependent and -independent regulation. |
15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
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