| Tbio | Zinc finger and BTB domain-containing protein 46 |
Function as a transcriptional repressor for PRDM1.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 5112 | 3.1e-06 |
| osteosarcoma | 7950 | 3.9e-05 |
| ovarian cancer | 8520 | 2.5e-03 |
| sonic hedgehog group medulloblastoma | 467 | 1.1e-02 |
| glioblastoma | 5792 | 1.6e-02 |
| adult high grade glioma | 3801 | 2.3e-02 |
| medulloblastoma, large-cell | 6241 | 3.0e-02 |
| subependymal giant cell astrocytoma | 2287 | 3.6e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Multiple Sclerosis | 540 | 0.0 | 2.7 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.100 | 2.3e-02 |
| atypical teratoid / rhabdoid tumor | -1.700 | 3.1e-06 |
| glioblastoma | -1.200 | 1.6e-02 |
| medulloblastoma, large-cell | -1.300 | 3.0e-02 |
| osteosarcoma | -2.985 | 3.9e-05 |
| ovarian cancer | 1.600 | 2.5e-03 |
| sonic hedgehog group medulloblastoma | 1.200 | 1.1e-02 |
| subependymal giant cell astrocytoma | -2.149 | 3.6e-02 |
MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQA 1 - 70 TVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDE 71 - 140 LAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHDGGSSYGKEDQEPKADGPDD 141 - 210 VSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVR 211 - 280 HITQQVEDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLG 281 - 350 PPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKC 351 - 420 PYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVG 421 - 490 IRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPEDPRGEAEELGEDDEGLAPEDA 491 - 560 LLADDKDEEDSPRPRSPPGGPDKDFAWLS 561 - 589 //
