Tbio | Zinc finger and BTB domain-containing protein 46 |
Function as a transcriptional repressor for PRDM1.
Comments
Disease | Target Count | P-value |
---|---|---|
osteosarcoma | 7933 | 3.35736190287396E-12 |
atypical teratoid / rhabdoid tumor | 4369 | 3.06431623928856E-6 |
ovarian cancer | 8492 | 0.00246176269080103 |
sonic hedgehog group medulloblastoma | 1482 | 0.0114451265802189 |
glioblastoma | 5572 | 0.0163479214916403 |
adult high grade glioma | 2148 | 0.0229864133773641 |
medulloblastoma, large-cell | 6234 | 0.0299564762840136 |
subependymal giant cell astrocytoma | 2287 | 0.0362177331752426 |
Disease | Target Count | Z-score | Confidence |
---|---|---|---|
Multiple Sclerosis | 498 | 0.0 | 2.0 |
Disease | log2 FC | p |
---|---|---|
osteosarcoma | -3.375 | 0.000 |
atypical teratoid / rhabdoid tumor | -1.700 | 0.000 |
glioblastoma | -1.200 | 0.016 |
medulloblastoma, large-cell | -1.300 | 0.030 |
adult high grade glioma | -1.100 | 0.023 |
sonic hedgehog group medulloblastoma | 1.200 | 0.011 |
subependymal giant cell astrocytoma | -2.149 | 0.036 |
ovarian cancer | 1.600 | 0.002 |
Species | Source |
---|---|
Chimp | OMA EggNOG |
Macaque | OMA EggNOG Inparanoid |
Mouse | OMA EggNOG Inparanoid |
Rat | OMA EggNOG Inparanoid |
Dog | OMA EggNOG |
Horse | OMA EggNOG Inparanoid |
Cow | OMA EggNOG Inparanoid |
Opossum | EggNOG Inparanoid |
Platypus | OMA EggNOG Inparanoid |
Chicken | OMA EggNOG Inparanoid |
Anole lizard | OMA EggNOG Inparanoid |
Zebrafish | OMA Inparanoid |
PMID | Text |
---|---|
23739915 | A single nucleotide polymorphisn in ZBTB46, rs6062314, is associated with an increased genetic risk for multiple sclerosis. |
MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQA 1 - 70 TVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDE 71 - 140 LAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHDGGSSYGKEDQEPKADGPDD 141 - 210 VSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVR 211 - 280 HITQQVEDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLG 281 - 350 PPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKC 351 - 420 PYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVG 421 - 490 IRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPEDPRGEAEELGEDDEGLAPEDA 491 - 560 LLADDKDEEDSPRPRSPPGGPDKDFAWLS 561 - 589 //
PMID | Year | Title |
---|---|---|
25218447 | 2014 | Uncovering global SUMOylation signaling networks in a site-specific manner. |
23739915 | 2013 | MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. |
23251661 | 2012 | Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. |
23186163 | 2013 | Toward a comprehensive characterization of a human cancer cell phosphoproteome. |
21833088 | 2011 | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. |
21297633 | 2011 | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. |
15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. |
12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
12136098 | 2002 | NotI flanking sequences: a tool for gene discovery and verification of the human genome. |
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