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Tbio
LRRTM1
Leucine-rich repeat transmembrane neuronal protein 1

Protein Summary
Description
Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295057
  • ENSP00000295057
  • ENSG00000162951
  • ENST00000409148
  • ENSP00000386646
  • ENST00000417012
  • ENSP00000393562
  • ENST00000433224
  • ENSP00000414523
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.56
transcription factor
0.56
cell type or tissue
0.54
cellular component
0.54
cell line
0.5


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.91   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 208   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.91   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 208   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0