| Tbio | Leucine-rich repeat transmembrane neuronal protein 1 |
Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Comments
| Disease | Target Count |
|---|---|
| Schizophrenia | 1160 |
| Disease | Target Count | P-value |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 5112 | 3.2e-05 |
| medulloblastoma, large-cell | 6241 | 9.2e-04 |
| adult high grade glioma | 3801 | 9.6e-04 |
| group 3 medulloblastoma | 4104 | 1.5e-03 |
| glioblastoma | 5792 | 2.4e-03 |
| astrocytic glioma | 2597 | 5.7e-03 |
| ependymoma | 4679 | 2.1e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Choanal Atresia | 42 | 3.339 | 1.7 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -2.200 | 9.6e-04 |
| astrocytic glioma | -1.300 | 5.7e-03 |
| atypical teratoid / rhabdoid tumor | -2.600 | 3.2e-05 |
| ependymoma | -1.300 | 2.1e-02 |
| glioblastoma | -1.500 | 2.4e-03 |
| group 3 medulloblastoma | -2.800 | 1.5e-03 |
| medulloblastoma, large-cell | -2.800 | 9.2e-04 |
MDFLLLGLCLYWLLRRPSGVVLCLLGACFQMLPAAPSGCPQLCRCEGRLLYCEALNLTEAPHNLSGLLGL 1 - 70 SLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLR 71 - 140 SVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFK 141 - 210 LTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVP 211 - 280 HLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLNNFQGRYDGNLQCASPEYAQG 281 - 350 EDVLDAVYAFHLCEDGAEPTSGHLLSAVTNRSDLGPPASSATTLADGGEGQHDGTFEPATVALPGGEHAE 351 - 420 NAVQIHKVVTGTMALIFSFLIVVLVLYVSWKCFPASLRQLRQCFVTQRRKQKQKQTMHQMAAMSAQEYYV 421 - 490 DYKPNHIEGALVIINEYGSCTCHQQPARECEV 491 - 522 //
