Protein Summary
Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.
- ENST00000280020
- ENSP00000280020
- ENSG00000150477
- ENST00000586135
- ENSP00000467507
- ENST00000586501
- ENSP00000470371
- ENST00000591619
- ENSP00000465550
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.91 | ||
kinase perturbation | 0.84 | ||
cell type or tissue | 0.63 | ||
virus perturbation | 0.59 | ||
transcription factor binding site profile | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.26 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 18 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.26 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 18 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0