Tbio CENPV Centromere protein V

Protein Summary

Description

Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis.

Uniprot Accession IDs

• Q7Z7K6
• B2RPK2
• Q3L8N5
• Q8NFH6
• CENP-V

Gene Name

• CENPV

Ensembl ID

• ENST00000299736
• ENSP00000299736
• ENSG00000166582

Symbol

• PRR6
• p30
• PRR6
• CENP-V
• 3110013H01Rik

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.97
transcription factor perturbation	0.94
disease perturbation	0.74
histone modification site profile	0.72
kinase perturbation	0.71

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 635.53   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 75   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 635.53   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0