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Tbio
CCDC91
Coiled-coil domain-containing protein 91

Protein Summary
Description
Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000381259
  • ENSP00000370658
  • ENSG00000123106
  • ENST00000539107
  • ENSP00000440513
  • ENST00000545336
  • ENSP00000438040

Symbol
  • GGABP
  • p56
  • HSD8
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
cell line
0.67
tissue sample
0.65
virus perturbation
0.64
trait
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.46   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 101   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.46   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0