LARP4
La-related protein 4
Protein Summary
RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744).
- ENST00000293618
- ENSP00000293618
- ENSG00000161813
- ENST00000347328
- ENSP00000340901
- ENST00000398473
- ENSP00000381490
- ENST00000429001
- ENSP00000415464
- ENST00000518444
- ENSP00000429077
- ENST00000522085
- ENSP00000429781
- PP13296
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.94 | ||
microRNA | 0.85 | ||
interacting protein | 0.84 | ||
tissue sample | 0.69 | ||
transcription factor binding site profile | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 19.64 (req: < 5)
Gene RIFs: 20 (req: <= 3)
Antibodies: 144 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 19.64 (req: >= 5)
Gene RIFs: 20 (req: > 3)
Antibodies: 144 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0