Tchem NEK10 Serine/threonine-protein kinase Nek10

Protein Summary

Uniprot Accession IDs

• Q6ZWH5
• A8MWG1
• B9ZVR0
• Q45VJ4
• Q6ZR11
• Q7Z671
• Q86XB1
• Q96MB3

Gene Name

• NEK10

Ensembl ID

• ENST00000295720
• ENSP00000295720
• ENSG00000163491
• ENST00000341435
• ENSP00000343847
• ENST00000383771
• ENSP00000373281
• ENST00000429845
• ENSP00000395849

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.93
protein domain	0.92
histone modification site profile	0.65
biological process	0.59
cell type or tissue	0.55

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Serine/threonine-protein Kinase Nek10

DTO Classes

Protein / Kinase / Protein Kinase / Other Group / Nek Family / Serine/threonine-protein Kinase Nek10

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.91   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 60   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.91   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1