Tdark | Protein FAM47E |
This locus represents naturally occurring read-through transcription between the neighboring FAM47E (family with sequence similarity 47, member E) and STBD1 (starch binding domain 1) genes on chromosome 4. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene. [provided by RefSeq, Jul 2011]
Comments
Disease | Target Count |
---|---|
Parkinson Disease | 105 |
Disease | Target Count | P-value |
---|---|---|
Breast cancer | 3099 | 2.02295841834503E-6 |
Disease | Target Count | Z-score | Confidence |
---|---|---|---|
Parkinson's disease | 364 | 0.0 | 2.0 |
MADRRRRLRPGTLAPVREGVNCRSRCFTKHKNGLKFPTSLHSRQLVFPRKGLDDFRKGCPPCTGLVTQVP 1 - 70 VEGFLPQIYHRAPQLAPKKRQIKLLKEADVLSKLSPAQQARKAFLEDVEAHLTPHPLALYLNLEEAMPIE 71 - 140 LLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMDL 141 - 210 LHENGPRPGLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKL 211 - 280 GYERKLQKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADLH 281 - 350 GTVAFKDFILSRGYRTPRFLENMYIGKECKRACNKTPIKRTQA 351 - 393 //
PMID | Year | Title |
---|---|---|
25064009 | 2014 | Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. |
21738487 | 2011 | Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. |
20967262 | 2010 | Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. |
19915575 | 2009 | Genome-wide association study reveals genetic risk underlying Parkinson's disease. |
15815621 | 2005 | Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |
14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. |
11181995 | 2001 | The sequence of the human genome. |
9847074 | 1998 | Toward a complete human genome sequence. |