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Tbio
MAMSTR
MEF2-activating motif and SAP domain-containing transcriptional regulator

Protein Summary
Description
Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318083
  • ENSP00000324175
  • ENSG00000176909
  • ENST00000356751
  • ENSP00000349192
  • ENST00000594582
  • ENSP00000471590

Symbol
  • MASTR
  • MASTR
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.58
cell line
0.58
tissue sample
0.54
transcription factor
0.54
cell type or tissue
0.44


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.07   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.07   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0