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Tbio Trem-like transcript 4 protein

Positively regulates Toll-like receptor TLR7 signaling in macrophages.

 Comments

Property Summary

NCBI Gene PubMed Count 7
PubMed Score 3.87
PubTator Score 2.97

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
psoriasis 6694 1.9e-06
ovarian cancer 8520 4.0e-05
osteosarcoma 7950 6.2e-04
diabetes mellitus 1728 1.6e-03
Disease Target Count Z-score Confidence
Ankylosing spondylitis 140 0.0 3.0

Expression

  Differential Expression (4)

Disease log2 FC p
diabetes mellitus 1.200 1.6e-03
osteosarcoma -1.013 6.2e-04
ovarian cancer -1.100 4.0e-05
psoriasis 2.400 1.9e-06

Synonym

Accession Q6UXN2 B7ZL92 TLT-4
Symbols TLT4
TLT-4

Gene

TREML4

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG Inparanoid

 UniProt Keyword (10)

 GO Component (2)

 GO Process (3)

 Compartment GO Term (7)

 HCA RNA Cell Line (8)

Pathway (3)

Gene RIF (2)

AA Sequence 

MAWGGVHTCCFHLCCCCSWPQGAVPEELHKHPGQTLLLQCQYSPKRGPYQPKSWCQQTSPSRCTLLVTSS      1 - 70
KPWTAVQKSHYTIWDKPNAGFFNITMIQLTQNDSGFYWCGIYNASENIITVLRNISLVVSPAPTTSPMWT     71 - 140
LPWLPTSTVLITSPEGTSGHPSINGSETRKSRAPACLGSGGPRFLVLVLCGLLLAKGLML              141 - 200
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Text Mined References (8)

PMID Year Title