Tbio SLC30A9 Zinc transporter 9

Protein Summary

Description

Acts as a zinc transporter involved in intracellular zinc homeostasis (PubMed:28334855). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).

Uniprot Accession IDs

• Q6PML9
• Q4W5B6
• Q7Z5I7
• Q8TBB2
• Q9Y6R2
• ZnT-9

Gene Name

• SLC30A9

Ensembl ID

• ENST00000264451
• ENSP00000264451
• ENSG00000014824

Symbol

• C4orf1
• HUEL
• HUEL
• ZNT9
• GAC63
• C4orf1
• BILAPES

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.9
histone modification site profile	0.85
interacting protein	0.85
transcription factor perturbation	0.84
kinase perturbation	0.76

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc30 Zinc Transporter Family / Zinc Transporter 9

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.64   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 142   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.64   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0