POMZP3
POM121 and ZP3 fusion protein
Protein Summary
This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
- ENST00000275569
- ENSP00000275569
- ENSG00000146707
- ENST00000310842
- ENSP00000309233
- ENST00000615241
- ENSP00000484663
- ENSG00000276464
- ENST00000619075
- ENSP00000477906
- POM121
- POM-ZP3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.72 | ||
tissue sample | 0.69 | ||
kinase perturbation | 0.6 | ||
tissue | 0.44 | ||
chemical | 0.43 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.81 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 103 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.81 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 103 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0