Tbio FOXR1 Forkhead box protein R1

Protein Summary

Description

This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q6PIV2
• B0YJ15
• Q08AS8
• Q86UT9
• Q8IXX2

Gene Name

• FOXR1

Ensembl ID

• ENST00000317011
• ENSP00000314806
• ENSG00000176302
• ENST00000531539
• ENSP00000433394
• ENST00000626640
• ENSP00000487495
• ENSG00000281277
• ENST00000634955
• ENSP00000489241

Symbol

• FOXN5
• FOXN5
• DLNB13

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.47
biological process	0.46
cellular component	0.42
chemical	0.41
tissue	0.4

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.39   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 73   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.39   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0