Protein Summary
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
- ENST00000334598
- ENSP00000334473
- ENSG00000153391
- ENST00000441607
- ENSP00000391457
- ENST00000592173
- ENSP00000465273
- C18orf37
- IES6
- hIes6
- C18orf37
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.92 | ||
transcription factor perturbation | 0.8 | ||
virus perturbation | 0.76 | ||
cellular component | 0.74 | ||
tissue sample | 0.64 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.79 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 26 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.79 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 26 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0