Tbio VWA1 von Willebrand factor A domain-containing protein 1

Protein Summary

Description

Promotes matrix assembly. VWA1 belongs to the von Willebrand factor (VWF; MIM 613160) A (VWFA) domain superfamily of extracellular matrix proteins and appears to play a role in cartilage structure and function (Fitzgerald et al., 2002 [PubMed 12062410]).[supplied by OMIM, Nov 2010]

Uniprot Accession IDs

• Q6PCB0
• A8K692
• B3KUA1
• E9PB53
• Q7L5D7
• Q9H6J5

Gene Name

• VWA1

Ensembl ID

• ENST00000338660
• ENSP00000423404
• ENSG00000179403
• ENST00000476993
• ENSP00000417185

Symbol

• WARP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
PubMedID	0.63
histone modification site profile	0.62
tissue	0.6
transcription factor	0.53
small molecule perturbation	0.52

Protein Classes

PANTHER Classes

Protein / Receptor / Von Willebrand Factor A Domain-containing Protein 1

DTO Classes

Protein / Receptor / Von Willebrand Factor A Domain-containing Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 467.83   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 67   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 467.83   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0