Property Summary

NCBI Gene PubMed Count 6
PubMed Score 2.12
PubTator Score 0.36

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count
non-small cell lung carcinoma 413
Disease Target Count P-value
lung carcinoma 2844 2.12970335810212E-31
psoriasis 6685 2.20898046614393E-23
non-small cell lung cancer 2798 5.60881720006438E-13
tuberculosis 1563 1.00451686553329E-7
nasopharyngeal carcinoma 1056 1.5065390928484E-7
lung adenocarcinoma 2714 3.3911737653135E-7
posterior fossa group A ependymoma 1511 2.92742800463708E-6
pilocytic astrocytoma 3086 1.8308165421554E-5
lung cancer 4473 4.71709986018878E-5
interstitial cystitis 2299 4.72892457916835E-5
cystic fibrosis 1670 3.62152753343174E-4
ovarian cancer 8492 9.72203416981894E-4
atypical teratoid / rhabdoid tumor 4369 0.00100409931750974
pediatric high grade glioma 2712 0.00413089620120326
mucosa-associated lymphoid tissue lymphoma 480 0.00469485506741982
osteosarcoma 7933 0.00486496688884191
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.00600066127719066
diabetes mellitus 1663 0.00688438463734729
subependymal giant cell astrocytoma 2287 0.00935539973485166
glioblastoma 5572 0.010161947506357
intraductal papillary-mucinous adenoma (IPMA) 2956 0.0112545977681055
facioscapulohumeral dystrophy 286 0.041226274377708

Expression

Synonym

Accession Q6P4A8 A8K4E9 Q9BVV3 Q9H625
Symbols

Gene

  Ortholog (10)

 MGI Term (1)

 GWAS Trait (1)

 CSPA Cell Line (2)

Gene RIF (1)

PMID Text
24667918 Microarray analysis indicates HIV-1 Tat-induced upregulation of phospholipase B domain containing 1 (PLBD1) in primary human brain microvascular endothelial cells

AA Sequence

MTRGGPGGRPGLPQPPPLLLLLLLLPLLLVTAEPPKPAGVYYATAYWMPAEKTVQVKNVMDKNGDAYGFY      1 - 70
NNSVKTTGWGILEIRAGYGSQTLSNEIIMFVAGFLEGYLTAPHMNDHYTNLYPQLITKPSIMDKVQDFME     71 - 140
KQDKWTRKNIKEYKTDSFWRHTGYVMAQIDGLYVGAKKRAILEGTKPMTLFQIQFLNSVGDLLDLIPSLS    141 - 210
PTKNGSLKVFKRWDMGHCSALIKVLPGFENILFAHSSWYTYAAMLRIYKHWDFNVIDKDTSSSRLSFSSY    211 - 280
PGFLESLDDFYILSSGLILLQTTNSVFNKTLLKQVIPETLLSWQRVRVANMMADSGKRWADIFSKYNSGT    281 - 350
YNNQYMVLDLKKVKLNHSLDKGTLYIVEQIPTYVEYSEQTDVLRKGYWPSYNVPFHEKIYNWSGYPLLVQ    351 - 420
KLGLDYSYDLAPRAKIFRRDQGKVTDTASMKYIMRYNNYKKDPYSRGDPCNTICCREDLNSPNPSPGGCY    421 - 490
DTKVADIYLASQYTSYAISGPTVQGGLPVFRWDRFNKTLHQGMPEVYNFDFITMKPILKLDIK           491 - 553
//

Text Mined References (10)

PMID Year Title
25645918 2015 Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum.
22952603 2012 Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
19159218 2009 Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
19019078 2009 The identification of a phospholipase B precursor in human neutrophils.
16541075 2006 The finished DNA sequence of human chromosome 12.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15193148 2004 Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
8125298 1994 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.