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Tdark
GTF2H2C
General transcription factor IIH subunit 2-like protein

Protein Summary
Description
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380729
  • ENSP00000370105
  • ENSG00000183474
  • ENST00000510979
  • ENSP00000422907
  • ENST00000619699
  • ENSP00000483148
  • ENSG00000274675
  • ENST00000621406
  • ENSP00000480471

Symbol
  • GTF2H2C_2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.68
cell line
0.48
small molecule perturbation
0.46
protein complex
0.45
microRNA
0.43


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.96   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 101   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.96   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0