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Tbio
LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

Protein Summary
Description
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301202
  • ENSP00000301202
  • ENSG00000167618
  • ENST00000351841
  • ENSP00000301203
  • ENST00000612901
  • ENSP00000478193
  • ENSG00000274084
  • ENST00000620256
  • ENSP00000477747
  • ENST00000621280
  • ENSP00000480904
  • ENSG00000277335
  • ENST00000622556
  • ENSP00000477535

Symbol
  • CD306
  • CD306
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.52
cell type or tissue
0.52
tissue
0.46
small molecule perturbation
0.43
chemical
0.41


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.65   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 196   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.65   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 196   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0