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Tbio
SCARA3
Scavenger receptor class A member 3

Protein Summary
Description
Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation. This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301904
  • ENSP00000301904
  • ENSG00000168077
  • ENST00000337221
  • ENSP00000337985

Symbol
  • CSR
  • CSR
  • APC7
  • CSR1
  • MSLR1
  • MSRL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.8
transcription factor perturbation
0.68
cellular component
0.67
PubMedID
0.66
tissue sample
0.65


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 219.48   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 110   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 219.48   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 110   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0