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NCBI Gene PubMed Count 2,432
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Gene RIF (2655)

PMID Text
27534049 Positive association of DRB1*03 allele with Atopic Bronchial Asthma has been found in Uzbek population.
27049564 This study findings indicate a possibly increased prevalence of neuromyelitis optica in Muslim Arabs in Israel with distinct (positive and negative) HLA associations.
27036319 HLA-DRB1*03 is associated with microalbuminuria in type 1 diabetes. HLA-DRB1*04 had no association.
26990204 One of the associated variants was also found to be linked with increased expression of MERTK in monocytes and higher expression of MERTK was associated with either increased or decreased risk of developing MS, dependent upon HLA-DRB1*15:01 status.
26967484 HLA-DRB1 alleles are associated with dermatitis herpetiformis in Chinese population.
26953725 alleles DRB1*01:01, DQ4, DQ7 and DQ8 are considered as susceptible to egg allergy
26919467 HLA-DRB1 variants better accounted for the association between MHC and susceptibility to RA and SLE than did 3 other HLA-DRB variants.
26915265 Cellular misfolded proteins rescued from degradation by MHC class II molecules seem to be involved in autoimmune diseases as a target for autoantibodies. (review)
26901036 HLA-DRB1*04 alleles are associated with pulmonary tuberculosis;the subtype HLA-DRB1*04:11:01 (p = 0.0019; OR = 2.23; 95% CI = 1.34 to 3.70) was associated with susceptibility to disease, while DRB1*04:07:01 (p<0.0001; OR = 0.02; 95% CI = 0.001 to 0.33)to protection.
26844284 the HLA-DRB1* haplotype appeared complementary with current serologic tools to predict good and poor responders in a treat to target strategy.
26829749 We found association of three variants in the region harboring genes encoding the class II human leukocyte antigens (HLAs): both located between HLA-DQA1 and HLA-DRB1
26818122 Significant increases in type 1 diabetes risk resulted from harboring the alleles HLA-DRB1*03:01 and HLA-DRB1*04:05. (Meta-analysis)
26818120 The carrier frequency of the HLA-DRB1*01 was higher in mixed connective tissue disease patients compared with controls, although the differences were not statistically significant.
26807576 The HLA-DRB1*0403 allele was significantly increased in autoimmune hepatitis patients with anti-gAChR antibodies compared with those without anti-gAChR antibodies.
26744784 The results of this study confirm that HLA-DRB1 alleles, genotypes and haplotypes are associated with MS risk in the Slovak population.
26740600 Significant negative associations with type 1 diabetes mellitus were observed for a total of 13 different HLA-DRB1 alleles.
26688538 HLA-DRB1*04 (OR 1.24, 95%CI 1.00-1.55, P = 0.0494), HLA-DRB1*08 (OR 1.45, 95%CI 1.14-1.86, P = 0.0030) and HLA-DRB1*16 (OR 1.39, 95%CI 1.04-1.87, P = 0.0269) were significantly associated with increased tuberculosis occurrence (Meta-Analysis)
26671138 DRB1*04 (DR4) (41/214 vs 42/400, Pc = 0.042, OR = 2.02, 95% CI 1.27-3.22) and DQB1*0302 (35/214 vs 32/400, Pc = 0.014, OR = 2.25, 95% CI 1.35-3.75) had significant positive association with AChR MG compared to controls, and
26656273 Studies indicate that Epstein-Barr virus (EBV) alone, HLA-DRB1*1501 alone or their interaction is associated with an elevated risks of multiple sclerosis (MS).
26634553 DRB1*03 and DRB1*07 may provide protective effects against tuberculosis susceptibility (Meta-Analysis)
26605347 The negative association we describe here supports the idea that the HLA-DRB1 *13 allele, possibly by its specific structural features, may as well confer resistance to several other AIDs.
26598658 Data indicate that the strongest risk factor for systemic juvenile idiopathic arthritis (sJIA) was HLA-DRB1*11.
26546900 an association of HLA-DRB1*13 with ulcerative colitis and also shows the protective role of HLA-DRB1*04 against the disease in people of Kerman.
26498496 The observed positive association between integrated HIV-1 DNA load and frequency of CD8(+)DR/DP/DQ(+) cells indicates that a close correlation between HIV persistence and immune activation continues during consistently suppressive therapy.
26456283 Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses.
26446064 An independent effect by HLA-DRB1*1501 was found, along with adolescent sun habits and the age of onset of multiple sclerosis.
26405068 Thyroid autoimmunity is highly prevalent in type 1 diabetes mellitus patients and the risk is modulated by HLA-DRB1 and HLA-DPB1 loci.
26396036 This study shows the universal applicability of the RNA-based sequencing approach to identify full-length coding sequences and to define the polymorphic content of HLA-DRB1 alleles.
26393471 carriage of HLA-DRB1*11 and *13 appears to increase the risk of uveitis in children with JIA.
26392055 A limit to the divergent allele advantage model supported by variable pathogen recognition across HLA-DRB1 allele lineages.
26367070 In our study we found HLA DR 13 was more frequent in healthy controls than in RRMS patients, suggesting a protective factor among Mexican Mestizo population.
26362370 Pharmacoresistant temporal lobe epilepsy associated with mesial hippocampal sclerosis is not determined by HLA class II alleles in the DRB1, DQB1, and DQA1 regions but the HLA DRB1*1302 allele exhibited a tendency to behave as a susceptibility factor
26307177 amino acid variations at peptide-binding pockets of HLA-DRB1 were associated with the persistence of AD in African-American children.
26235935 two different types of analysis in this single study showed the protective effect of the DRB1*1302 allele against progression from cervical intraepithelial neoplasia grade 1 to cervical intraepithelial neoplasia grade 2/3.
26199258 The HLA-DRB1*15 allele, the A*01/B*08/DRB1*03 haplotypes, and the homozygosity of HLA-A*01 and HLA-A*02 may play a presumptive predisposing factor in Acute Myeloblastic Leukemia.
26198919 HLA-DRB1*1501 haplotype is not associated with multiple sclerosis risk in a Kuwait cohort.
26168013 Data indicate interactions for 11 of 21 pairs of common HLA-DRB1-HLA-DQA1-HLA-DQB1 haplotypes.
26119197 HLA-DRB1*0301, as a genetic factor, seems to have an association with cholecystitis.
26091715 the HLA-DRB1*04 risk allele increases activity of a key proinflammatory, prosurvival transcription factor, NF-kB, specifically in CD4+ T cells and this increase is dependent on HLA-DR.
26088816 our results are consistent with the assumption that DRB1 and DQB1 alleles have critical role in susceptibility and protection for type 1 diabetes.
26056112 HLA-DRB1 may be a valuable marker to predict the risk for of pulmonary tuberculosis, especially in Asian populations (Meta-Analysis)
26022697 In late-onset SLE, HLA DR17 (DR3) was found more frequently compared with individuals without autoimmune disease.
25998395 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
25992516 the HLA-DRB1*15:01 allele was associated with susceptibility to multiple sclerosis in a sample population from Rio de Janeiro, Brazil and this association was more significant in female patients.
25975240 HLA-DRB1*04 is involved in predisposing patients to aspirin-exacerbated respiratory disease (AERD), whereas HLA-DQB1*0301 has a negative association with AERD.
25971824 HLA-DRB1*03 is associated with susceptibility to schizophrenia. DRB1*13 is protective for schizophrenia. DRB1*0301/DQB1*0201, DRB1*0401/DQB1*0301 and DRB1*1101/DQB1*0301 are haplotypes most conducive to disease susceptibility.
25965561 Linkage disequilibrium exists between TNF rs1800629 and HLA-DRB1 and HLA-DQB1 alleles in a Brazilian type-1 diabetes population.
25953150 The data in the present research demonstrated a strong positive association between HLA-B*4601,HLA-DRB1*0901, HLA-B*4601-DRB1*0901, and juvenile ocular MG in southern China.
25926086 A novel null HLA allele, HLA-DRB1*15:115N, has been identified in a Chinese family.
25919528 Among patients with rheumatoid arthritis, the HLA-DRB1 locus was associated with radiological severity and mortality.
25916813 Shared epitope alleles were overrepresented among IgG anti-CCP-positive RA patients, regardless of IgA anti-CCP status, and was not seen in patients with IgA anti-CCP alone. An interaction between ever smoking and shared epitope alleles was found.
25911099 highlights a potential contribution to MS risk also from interisotypic combination between products of neighboring HLA-DR15 haplotype alleles, in this case the DQA1/DRB1 combination.
25845749 lamotrigine-induced cutaneous adverse drug reactions are associated with HLA-DRB1*0405, -DQB1*0401 and -DQA1*0303
25832994 Amino acid position 74 in HLA-DRB1 is strongly associated with ACPA levels in ACPA-positive RA, as well as with RA susceptibility.
25824849 Data confirmed the lack of association between HLA-DRB1 and clinical response to IFNbeta among MS patients as previous studies had done.
25817017 dRbeta1 amino acid position 13 polymorphism is associated with giant cell arteritis susceptibility.
25787085 This study suggested that the HLA-DRB1*04, *09, *10, *15, and *16 gene polymorphisms may contribute to the risk of TB, especially in East Asians. But the HLA-DRB1*11 gene polymorphism may be a protective factor.
25777156 HLA-DRB1*04:05, characterized by serine at position 57, accounts for the detrimental association between the shared epitope and Sharp/van der Heijde score in Japanese patients with ACPA-positive rheumatoid arthritis.
25732927 Data suggest a genetic interaction between MAP2K4 and HLA-DRB1, and the importance of rs10468473 and MAP2K4 splice variants in the development of autoantibody-positive RA.
25708101 There is significant association of pemphigus vulgaris with HLA-DRB1*04:02:01 and *14:54 alleles in German, and with HLA-DRB1*04:02:01, *08:04:01 and *14:54 in Egyptian patients.
25700963 genetic polymorphism is associated with recurrent miscarriage; meta-analysis
25698175 When compared with healthy controls, neuromyelitis optica patients had over representation of HLA-DRB1*03 allele
25673541 DRB1*13 confirmed as a protective marker in HPV infection outcome.
25666956 Our results demonstrated the association of HLA-C*03 and HLA-DRB1*01 alleles with Macedonian autistic patients
25665771 no association between DRB1*13:01 and age related macular degeneration in American patients
25651370 The authors believe this to be the first research linking the haplotypes DRB1*1501/DQB1*0602 and DRB1*04/DQB1*0302 with Alzheimer's disease.
25636572 increase in the frequencies of DRB1 *07 allele among Takayasu arteritis patients in the Chinese Han population
25636569 genetic polymorphism is associated with rheumatoid arthritis in Thai patients
25634309 We found no association between visual acuity and possession of the HLA-DRB1*1501 allele.
25626601 The study aims to assess the distribution of HLA-A, -B, -Cw and DRB1 alleles in Moroccan patients with ankylosing spondylitis (AS) and to compare the clinical features of AS and the frequencies of HLA-B27 in patients from Morocco.
25611558 HLA-DRB1*03:01 is the strongest genetic modifier of disease severity in autoimmune hepatitis type-1.The HLA-DRB1*04:01 allele was independently associated with presentation at older age and a female predominance in autoimmune hepatitis type-1.
25604634 Data suggest that CCR2 +190 G/A polymorphism may increase the susceptibility to MS, but its action seems to be restricted to individuals who do not possess the major risk allele HLA-DRB1*15:01.
25583844 The results indicate that latitude and HLA-DRB1 alleles independently affect the emergence of cerebrospinal fluid IgG abnormalities in Japanese patients with multiple sclerosis
25582848 Results suggest that structural heterogeneity of the HLA-DRB1 peptide binding pocket P7 and P9 might play a role in the pathogenesis of primary Sjogren's syndrome (pSS).
25582808 Our study provided initial evidence that HLA-DRB1( *)13:02 and genes involved in immune-related pathways are associated with panic disorder.
25559196 High-density SNP typing of the MHC in >32,000 individuals with inflammatory bowel disease implicating multiple HLA alleles, with a primary role for HLA-DRB1*01:03 in both Crohn's disease and ulcerative colitis
25533202 Mutation in amino acid positions 11, 13 and 26 of HLA-DRbeta1 is associated with systemic lupus erythematosus.
25531278 The most frequent alleles were HLA-DRB1*07:01 in Kazakh population.
25524867 With some exceptions, the genetic risk conferred by HLA-DRB1 in African Americans is similar to that in individuals of European ancestry. However, amino acid position 57 was associated with RA in African Americans, but positions 71 and 74 were not.
25521205 HLA-DRB1 is the main risk factor for primary sclerosing cholangitis in the MHC.
25506722 DRB1*03:01 and *03:02 are novel alleles associated with sarcoidosis susceptibility and course in African Americans.
25413106 Among 17 alleles so far observed only once in our population, 6 (A*24:41, B*07:02:28, B*35:03:03, B*39:40N, DRB1*13:23 and DRB1*14:111) belong to very rare alleles, 2 (B*44:16 and DRB1*01:31) belong to rare alleles
25383971 HLA-DRB1 is a major contributor to resistance against enteric fever, presumably through antigen presentation
25382027 this meta-analysis demonstrates a strong association between HLA-DR4/HLA-DRB1*04 and VKH.
25346274 Results from an HLA-DRB1 allele polymorphisms study show the allele DRB1*13:01 significantly associated with an increased risk to develop colorectal carcinoma tumor.
25337265 HLA-DRB1*1501 and DQB1*0602 alleles may influence the immune response to HPV16 infection and decrease the risk of invasive cervical cancer among Uighurs and Hans in Xinjiang, China.
25329634 Poisson Regression was employed to assess risk genotypes. DRB1*04, DQA1*03 and DQB1*03:02 were associated with TST response in this population.
25325831 There is a statistically significant correlation between the HLA-DRB1*03 allele and the occurrence of CHB in the Han Chinese population, and the HLA-DRB1*03 allele may be a susceptibility allele for this disease.
25324153 An interaction was observed between passive smoking and carriage of HLA-DRB1*15 in development of multiple sclerosis. Priming of the immune response in the lungs may subsequently lead to MS in people with a genetic susceptibility to the disease.
25298310 The results of this study suggested that HLA-DRB1*15 influences the progression of brain pathology in primary progressive multiple sclerosis.
25274017 HLA-DR12 may have a role in the pathogenesis of Lofgren's syndrome in Japanese patients [case report and review]
25256132 Increase in HLA-DRB1*04 haplotype is associated with type 1 diabetes.
25249698 Genetic variants of CYP21A2 associated to autoimmune Addison's disease(AAD) are in linkage disequilibrium with the main AAD risk locus HLA-DRB1, and CYP21A2 does not constitute an independent susceptibility locus.
25244652 prevalence of newer alleles: HLA-A*24:23, A*30:10, DRB1*08:11, DRB1*15:03, and DRB1*15:06.
25240755 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
25223600 Comparison of the risk allele profile in this cohort with the risk alleles previously identified in patients with systemic sclerosis, determined using the same methods and same control population, revealed one allele in common, DRB*04:04
25217962 Data indicate HLA-DQA1*02:01-HLA-DRB1*07:01 haplotype acociate with pancreatitis induced by thiopurine immunosuppressants.
25186300 SNP rs2395185 linked with HLA-DRB1*0405 is a genetic determinant of antinuclear antibody production in the Japanese population.
25184637 These findings of HLA-DRB1 alleles in association with Chinese SSc provide the growing knowledge of genetics of SSc, and indicate that the genetic heterogeneity among ethnicities may significantly impact the complex trait of SSc.
25130147 HLA-DRB1*1501/1501 and bigenic genotypes of the HLA- DRB1*1501/x- CD24 v/v may influence on disease severity in Iranian MS patients.
25119922 The DRB1*09 and DRB1*13 alleles of HLA-DRB1 may contribute to the susceptibility of recurrent spontaneous abortion.
25103892 this study provides an insight into the role of shared epitope and suggests that *0401 and *0402 molecules can produce all types of cytokines although the requirement for producing proinproinflammatorycytokines like TH1/TH17 may differ.
25078644 Demonstrate a strong positive link between the haplotype HLA DRB1*15 and sarcoidosis in a Turkish Caucasian population and a potential protective effect of HLA DRB1*11 from extra-pulmonary involvement of disease.
25064442 The frequency of the HLA-DRB1* 11/15 genotype detected in the present study showed that this genotype is partially significant factor for MS susceptibility and development in Iran.
25037176 We investigated the association of HLA alleles and KIR ligands according to oligoclonal band status in multiple sclerosis patients.
25034406 HLA-DRB1*15:01 allele protects from asthma susceptibility.
25009391 HLA DRB1*07 allele is a protective factor against cirrhosis in Turkish patients with chronic hepatitis B.
24979673 HLA-DRB1*15:01, HLA-DQB1*06:02, HLA-B*46:01 and HLA-DRB1*09:01 may be associated with severity of aplastic anemia.
24970932 results suggest a mechanism of allergy whereby HLA-DRB1 alleles that confer high-affinity binding to asparaginase epitopes lead to a higher frequency of reactions.
24964187 HLA-DRB1*15 status has a significant association with the extent of inflammation in the multiple sclerosis motor cortex
24963477 results demonstrated that the HLA-A*68, HLA-B*51, and HLA-DRB1*15 alleles were significantly more frequent in HD patients in comparison to controls
24962747 implicated in the susceptibility to asthma in the pediatric population in India
24954875 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
24919928 Data indicate that carrying both the -330 T interleukin-2 (IL2) and the HL- DRB1* 1501 allele showed the most susceptibly effect to multiple sclerosis.
24911054 our findings support the protective role of DRB1*13:02 in the pathogenesis of ACPA-positive RA.
24903971 Results didn't show any association between HLA-DRB1 allelic group distributions and susceptibility to acute kidney transplant rejection although it showed an association between HLA-DRB1 allele in kidney transplant recipients and hepatitis C infection.
24853027 Analysis confirms the role of the DRB1-DQB1 haplotype in conferring Multiple sclerosis disease predisposition. of two HLA class II haplotypes associated with the disease in Sardinia, the rare predisposing DRB1*15:01-DQB1*06:02 and the widespread protective DRB1*16:01-DQB1*05:02.
24806356 Lichen planopilaris appears to be over-represented in non-Ashkenazi Jewish patients and is associated with an increased frequency of HLA DRB1*11 and DQB1*03 alleles.
24793468 a new Guillain-Barre syndrome predisposition associated with HLA-DRB1*14 and DRB1*13
24763718 The HLA-DRB1*15 haplotype was strongly negatively associated to JCV sero-status in Scandinavian MS cases (OR = 0.42, p = 7x10(-15)) and controls (OR = 0.53, p = 2x10(-5)).
24760193 There is no significant difference in the HLA-DRB1 allele's frequency between sporadic and familial rheumatoid arthritis (RA). Therefore, familial aggregation is not associated with RA severity.
24758334 This study is important and interesting, as it is the first report in Indian haemophilia patients on the association of HLA (type II) alleles to inhibitor development and also highlights a novel HLA allele association with FVIII inhibitors.
24750313 This study showed that no statistically significant genotype differences between CIDP patients and healthy individuals according to the B-Y criterion, although there was a tendency for increased DRB1*11.
24738569 The HLA typing results revealed that HLA DQA1*0501, HLA DQB1*0302, and HLA DRB1*11 alleles were common in all four family members with focal epithelial hyperplasia. HLA DRB1*04 allele was detected in three of them.
24724911 Individuals carrying the HLA-DRB1*07:01 allele present an increased risk for Di(a) alloimmunization.
24691290 HLA-A, -B and -DRB1 allele frequencies and their haplotype frequencies in 21,918 Chinese residents living in Liaoning Provinc, were investigated.
24661105 HLA-DRB1*03 and DRB1*11 may be the primary susceptibility HLA-DRB1 alleles associated with GD in Romanian population, whereas HLA-DRB1*01 and DRB1*15 seem to be protective.
24641503 distinct HLA allele combination, HLA-DRB1*04/*15, was identified as a risk factor for EPM in all patients (25 of 50 with DRB1*04/15 had EPM). In conclusion, EPM are common in non-LS sarcoidosis.
24632584 Our results confirmed the role of HLA sharing in RPL and revealed that HLA-DRB1 typing may be a valuable prognostic factor for the leukocyte therapy outcome.
24628273 Haplotyping was done on 91 Southern Europe celiac patients. 96.7% carried the HLA-DQ2 and 4.4% carried the HLA-DQ8 haplotype.
24602055 We found DRB1*04:02 and DQB1*03:02 alleles to be associated with severe pemphigus vulgaris.
24598797 results provide strong evidence for a multilevel risk model for HLA-DRB1*03:01 in SLE, where the association with anti-Ro and anti-La antibody-positive SLE is much stronger than SLE without these autoantibodies.
24597629 HLA-DRB1 alleles are associated with anti-neutrophil cytoplasmic antibodies in Han and Uyghur patients with ulcerative colitis in China.
24551099 The HLA-DRB1 family alleles and specific alleles might influence the susceptibility or resistance to cervical cancer.
24517468 Small duct primary sclerosing cholangitis without inflammatory bowel disease is associated with HLA-DRB1*13:01.
24505475 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
24500647 There is a significant interaction between absence of HLA-A*02 and obesity, regardless of HLA-DRB1*15 status, .in relation to the risk of developing multiple sclerosis
24491062 HLA-DRB1 gene polymorphism and aplastic anemia
24490781 The HLA-A*32, HLA-DQB1*05 and HLA-DRB1*01 allele frequencies may be associated with the development of seborrhoeic dermatitis.
24403192 The C allele of rs9272143 ( HLA-DRB1)conferred protection against cervical cancer , which is associated with HLA-DRB1, whereas the T allele of rs2516448 increased the susceptibility to cervical cancer (with the same association shown with MICA
24397488 HLA-DQA1*03:02 HLA-DRB1*08:01 and DRB1*08:03 occurred more frequently in patients with drug resistant tuberculosis than in controls.
24381092 Report strong increase in HLA-DRB1 allele frequency in Albanian rheumatoid arthritis patients.
24321473 Recognition of characteristic chorioretinal lesions in otherwise unexplained pediatric panuveitis, supported by selective HLA class II DNA typing, is useful in narrowing diagnostic possibilities and directing further evaluations.
24316141 donor-recipient mismatch determines graft outcome after renal transplantation
24297382 possession of HLA-DRB1 shared epitope alleles contribute to the development of anti-citrullinated peptide antibodies in anti-cyclic citrullinated peptide(-) rheumatoid arthritis.
24295149 This pilot study detected a difference between HLA-DRB1 alleles in susceptibility to rheumatoid arthritis-related pulmonary fibrosis, compared to rheumatoid arthritis alone.
24291122 study shows that the pathophysiology of familial hypersensitivity (HF) pneumonitis is influenced by HLA genes and particularly a gene-to-gene interaction between TNF-238G homozygous and HLA-DRB1*04 alleles and haplotypes may contribute to the susceptibility to HP in Mexicans
24282030 Polymorphisms in the HLA-DR region is associated with non-response to hepatitis B vaccination.
24268496 DQ B1 but not HLA-DR typing, TNF-alpha levels, HCRTR1 and HCRTR2 were higher in narcolepsy-cataplexy/schizophrenia patients.
24260237 Data proved that INS and PTPN22 genes marginally influence T1D risk in all risk HLA-DRB1 genotype categories.
24190431 Observed citrullinated vimentin- and aggrecan-specific CD4(+) T cells in the peripheral blood of HLA-DRB1*04:01(+) rheumatoid arthritis. Autoreactive T cell numbers correlated with disease activity and were deficient in regulatory T cells.
24161032 HLA-DRB1*04, *0401, *0404, *0405 and *0410 are risk factors for rheumatoid arthritis in Chinese populations.
24103044 The new HLA alleles discovered include DRB1*04:11:03, DRB1*10:05, DRB1*15:94 and DRB1*16:22.
24103024 By a nucleotide exchange at position 227 (T/A) of the coding HLA-DRB1 sequence.
24055898 The HLA-B*39 allele increases type 1 diabetes risk conferred by HLA-DRB1*04:04-DQB1*03:02 and HLA-DRB1*08-DQB1*04 class II haplotypes.
24046013 Data indicate the association of HLA-A, -B, -C, and -DRB1 incompatibilities with adverse outcome in hematopoietic stem cell transplantation (HSCT).
24033735 HLA-DRB1*09 and HLA-DRB1*14 alleles associated with retinopathy of prematurity
24029438 There is close relationship between the polymorphism of HLA-DRB1 alleles and drug use with HIV infection.
24024195 Polymorphisms in the NRAMP1 gene, VDR gene, HLA-DRB1 gene, and HLA-DQB1 gene are statistically associated with susceptibility to TB in the Chinese Kazakh population.
23994122 results conclude that while HLA-DRB1*15 is associated with increased susceptibility to pulmonary tuberculosis, HLA-DRB1*16 allele confers protection against mycobacterial infection in the Sahariya tribe
23993985 This study provides a replication of the highly significant associations of both HLA-DRB1( *)16,-DRB1( *)14 and -DQB1( *)05 with MuSK-MG.
23992015 HLA-DRB1 polymorphisms are not associated with risk of cervical squamous epithelial cell carcinoma
23968403 There is a significant DRB1and DQB1 allele and haplotype association with rheumatoid arthritis susceptibility and protection
23958186 put forward the hypothesis that besides different environmental factors there is probably also a particular genetic risk profile in Congolese patients, different from the HLA-DRB1 shared epitope
23953521 Report HLA-DRB1 allele and haplotype frequency in Turkish chronic kidney disease patients undergoing renal dialysis.
23951151 HLA-DRB1*04:01 and HLA-DPB1*04:01 alleles were detected at higher frequencies in influenza-seroprotected compared with non-seroprotected individuals.
23849771 A role for HLA-DRB1*15 allele molecules in the predisposition of Moroccan patients to Multiple sclerosis.
23837503 This study demonistrated that HLA DRB1*15 allele was related with an earlier manifestation of the first MS symptoms, progressive course of the disease and higher degree of disability.
23835632 associated myelopathy/tropical spastic paraparesis was significantly associated with HLA-B 07 and HLA-DRB1 01:01.
23834030 No differences related to family history of psoriasis were observed in HLA-DRB1*1501 polymorphism.
23809616 Significant associations existed between HLA-DRB1*08:03 allele and primary biliary cirrhosis.
23793423 this is the first study to show HLA-DRB1 and HLA-DQB1 associations with systemic lupus erythematosus in the Saudi population.
23793098 HLA-DRB1 variant expression has a considerable impact on the control of HIV replication.
23791106 Coding variants at a single hexa-allelic amino acid position (13) of HLA-DRB1 influence follicular lymphoma risk.
23745951 Results indicate that HLA-DRB1, HLA-DQA1 and HLA-DQB1 alleles were identified in 100 Qashqais and 66 Turkmens.
23742216 The unusual DRB1*08:01 haplotype carrying DRB3*02:02 has been confirmed in a Dutch family.
23739956 A central role is identified for microglial histocompatibility complex (MHC)II in activating immune responses to alpha-synuclein in Parkinson's disease.
23737967 HLA-DRB1 genotypic risk for developing ACPA positive RA
23729440 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
23724919 Data indicate that 44 HLA-A, 67 HLA-B and 48 HLA-DRB1 most probable alleles were identified.
23674880 HLA-DRB1*04*13*14 and DRB1*08 may contribute to the clinical heterogeneity of ulcerative colitis between Han and Uyghur UC patients.
23638805 The most frequent haplotypes that may be associated with susceptibility to American cutaneous leishmaniasis were A*02 B*44 DRB1*07 (P = 0.0236) and A*24 B*35 DRB1*01 (P = 0.0236).
23637323 HLA-DRB1*09:01 differs from shared epitope alleles with regard to anti-CCP levels and interaction with smoking, suggesting a distinct mechanism of HLA-DRB1*09:01 in the pathogenesis of RA that may bypass anti-CCP formation.
23636621 Suggest that DRbeta1*04 was strongly associated with rheumatoid arthritis in patients from Western India, whereas DRbeta1*03 and *14 may be protective alleles for RA.
23636221 Studies indicate that HLA antigens DR8, B*57:03 and DRB1*07:01 were associated with hepatitis C virus (HCV) clearance.
23628399 HLA-DRB1*11:01, *08:02, DQB1*03:01 and DRB1*11:01-DQB1*03:01 haplotype were strongly associated with disease susceptibility to severe RRP in Korean patients.
23613482 Thyroxin substitution was associated with a small and non-significantly increased risk of ACPA-positive rheumatoid arthritis in those without the SE allele, while the use of thyroxin increased the risk substantially among SE carriers.
23593151 propensity to MS observed in Sardinian population carried by the various HLA-DRB1-DQB1 molecules can be due to functional peculiarity in the antigen presentation mechanisms
23590002 differed from non-HPV16 subjects in their positive association with DRB1*1501
23588515 Our results indicate that HLA-DRB1*01, *04, and *10 alleles are related with RA, while HLA-DRB1*11 and *13 protect against RA in the Syrian population
23577190 PADI4 risk allele and HLA-DRB1 shared epitope are independent genetic risks for radiographic progression in Japanese rheumatoid arthritis patients
23556450 HLA-DRB1*1501 and defined VDR SNPs affect the ability of macrophages to counter infection with Mycobacterium tuberculosis.
23555798 analysis of polymorphic sequences for HLA-DRB1 genotyping
23555757 propensity to multiple sclerosis in Sardinia could be partly linked to distinct peptide-MHC (HLA-DRB1) interaction and binding characteristics of the antigen presentation mechanism
23551624 Data indicate an association between pemphigus vulgaris (PV) and DRB1*14:54.
23543758 Four peptides bound to DRB1*08:01 with reasonable affinity, but only one of these bound to DRB1*11:01.
23507476 we demonstrated that two ALCAM polymorphisms, rs11559013 and rs34926152, although not associated with Multiple sclerosis itself, modify HLA-DRB1*1501 effect
23502333 genetic polymorphism is associated with bullous pemphigoid in Iranian patients
23485854 Carriage of HLA-DRB1*15 significantly increases the extent of demyelination, parenchymal and lesional spinal cord inflammation in multiple sclerosis.
23477965 In multiple sclerosis patients HLA-DRB5 expression is associated with HLA-DRB1*1501 susceptibility allele.
23421483 Data indicate that DR7-DQ2 haplotype consists mainly or only of DRB1*07-DQB1*02:02, and not DRB1*07-DQB1*02:01:01.
23413297 DRB1-15 and infectious mononucleosis may be involved in the same causal process leading to multiple sclerosis
23407388 We identified HLA-DRB1 alleles associated with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population and demonstrated a shared susceptibility of DRB1*09:01 between the diseases as well as its effect on autoantibody production.
23404077 In Thai patients with systemic sclerosis, there was no significant association between clinical manifestations among individuals who carried HLA-DRB1*15:02 or DRB5*01:02. The HLA-DRB1*04 was a protective allele against Thai SSc patients.
23402837 Association of HLA-DR-DQ polymorphisms with diabetes in Tunisian patients.
23398374 Data suggest HLA-DRB1*03 haplotype splits (in African Americans) into HLA-DRB1*03:01 which confers susceptibility to type 1 diabetes and HLA-DRB1*03:02 (rarely observed in those with European ancestry) which confers protection from type 1 diabetes.
23392276 Data indicate that HLA-DRB1*1501 was associated with multiple sclerosis (MS) (International Classification of Disease version 9-CM (ICD9) 340, P=0.023).
23391249 No significant association between hepatitis C virus infection and HLA DRB1* alleles observed
23380142 Data indicate that DRB1*13:02-DQB1*06:04 and DRB1*15:01-DQB1*06:02 haplotypes share the same DQA1*01:02 allele.
23380141 Results suggest that HLA-DRB1*07/*15 genotype in combination with tumor necrosis factor (TNF)-alpha polymorphisms influence progression to dengue hemorrhagic fever (DHF).
23378606 The study identifies Nox2 as the central molecule in insulin resistance-mediated oxidative stress and vascular dysfunction.
23376085 there is no significant tendency of the mutant gene contribution to the resistance after the elimination of the HLA-B*14:02-DRB1*01:02 linked mutants.
23331206 no statistically significant differences were found between bronchial asthma and HLA-DRB1, -DQB1 alleles in the Slovak population
23328091 HLA-B*5801 and HLA-DRB1*0102 were independently associated with increased likelihood of hepatotoxicity
23321320 HLA-DQA1(*)0601 and HLA-DRB1(*)0405 genetic susceptibility loci were associated with the progression from chronic hepatitis C to liver cirrhosis.
23321172 Mutation in HLA-DRB1 rs2308765 was associated with increased risk of left ventricular dilatation in elderly patients with hypertension.
23318129 There is an HLA-dependent risk of developing pain after surgery or lumbar disc herniation. This is mediated by the DRB1*04 - DQB1*03:02 haplotype.
23317308 The frequency of the HLA-DRB1*04:01 allele was significantly higher in Iranian patients with aggressive periodontitis.
23312038 A high titer of Epstein-Barr nuclear antigen EBNA1 is significantly associated with HLA DRBI*15:01 status in Indian patients with multiple sclerosis, but not in healthy controls.
23303446 There is an association of generalized vitiligo with MHC class II loci in patients from the Indian subcontinent.
23302880 Heterozygotic DRB1*04:01+ individuals showed very low T cell responses to JC virus together with normal anti-VP1 antibody levels and no urinary viral shedding, indicating a dominant-negative effect of this allele on global virus-directed T cell responses.
23291585 The HLA-DRB1-HLA-DQA1 HLA class II region contributes to visceral leishmaniasis susceptibility in India and Brazil.
23283466 results demonstrated the existence of a genetic susceptibility associated with the clinical forms of leprosy. The low frequency of the HLA-DRB1*11 allele should be further studied to investigate the possible protective effect of this allele.
23278646 There is a correlation between HLA-DRB1*15:01, -DRB1*11:04, DRB1*11:01, -DRB1*04 and -DRB1*07:01 alleles and allergic bronchopulmonary aspergillosis susceptibility and suggest that HLA-DQB1*02:01 is a disease resistance allele.
23260142 The structure of the HLA-DM-HLA-DR complex shows major rearrangements of the HLA-DR peptide-binding groove.
23257407 HLA-DRB1/HLA-DQA1 rs9271366 may play a part in influencing the systemic lupus erythematosis susceptibility in Malays and Chinese in Malaysia.
23253237 Study indicates that associate and protective HLA-DRB1 allele distributions are different in autoantibody positive RA and autoantibody negative RA patients.
23246582 Data indicate that the frequencies of CD11c, CD11c/CD86, HLA-DR/CD86, CD83 and CD80 were significantly high, while CD11c/HLA-DR was low in Hepatitis E infection.
23243276 Anti-IFN-gamma autoantibodies may play a critical role in the pathogenesis of nontuberculous mycobacterial infections and reactivation of latent varicella-zoster virus infection and are associated with HLA-DRB1*16:02 and HLA-DQB1*05:02.
23232601 antibody titers for Epstein-Barr nuclear antigen 1 were higher in pediatric multiple sclerosis patients who were HLA-DRB1 positive.
23225889 Identification of the peptide recognized by CD4 single-positive T cells reveals a new human HY epitope, TGKIINFIKFDTGNL, encoded by RPS4Y and restricted by HLA-DR7.
23218978 For HLA class II alleles, strong increase in the frequency of DRB1*15 was observed in ARONJ group. results were reinforced on analysis of respective haplotypes, with DRB1*15-DQB1*06:02 being significantly associated with the development of ARONJ
23200758 Data indicate estimated HLA-A, -B, -C, -DRB1 haplotype and allele frequencies of donors within DKMS German Bone Marrow Donor Center with parentage from 17 different countries.
23186557 The distribution of the rs3135388 gene polymorphism is a risk factor for multiple sclerosis susceptibility in the Czech female population.
23184486 Susceptibility to psoriasis vulgaris is significantly associated with HLA-C*06 (odds ratio (OR) = 3.85), DRB1*07 (OR = 2.56) and DQB1*02 (OR = 1.09), respectively, whereas DRB*01 (OR = 0.05) is associated negatively.
23183775 Deleterious impact of HLA-DRB1 allele mismatch in sensitized recipients of kidney retransplants.
23180817 The shared epitope (SE), an HLA-DRB1-coded sequence motif that is the single most significant genetic risk factor for erosive rheumatoid arthritis, acts as a signal transduction ligand that potently activates osteoclastogenesis both in vitro and in vivo.
23180035 Review: HLA-DRB1*09:01 itself or other genes in tight linkage disequilibrium may play a role in ANCA-associated vasculitis in Japan.
23177929 This study demonistrated that HLA-DRB1 may increase risk for schizophrenia.
23176610 TNF-alpha-308 G/A polymorphism was strongly associated with HLA-A*2, -A*33, -B*58, and -DRB1*03 alleles in Han-nationality lung transplant recipients.
23171011 HLA DR1 appears to be associated with the development of basal cell cardinoma, as well as with the higher number of non melanoma lesions in renal transplant patients.
23170932 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
23152536 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
23139797 based on results, it is speculated that HLA-DRB1 alleles are associated with the susceptibility to sporadic Parkinson's disease in Chinese Han population, among them HLA-DRB1*0301 is a risk allele while the effect of HLA-DRB1*0406 deserves debate
23130884 this study reports a de novo HLA-DRB1*04 allele, DRB1*04:05:14, discovered in a Taiwanese unrelated volunteer bone marrow stem cell donor by a sequence-based typing method.
23119005 an additional CD susceptibility factor is present in the ancestral haplotype 8.1 but not in other DRB1*03ratio01-carrying haplotypes
23110937 Autistic children have significantly higher frequency of HLA-DRB1*11 allele than controls; in contrast, autistic children have significantly lower frequency of HLA-DRB1*03 allele than controls.
23100517 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
23090223 the present study reveals that younger blood donors and male blood donors who respectively exhibit the DRB1*08 and DRB1*09 alleles are more susceptible to intensification of hepatitis B virus infection.
23053058 study undertaken to genotype the HLA-DRB1*0101 allele and three DRB1*13 alleles using HLA-tagging SNPs for detection of their association with schizophrenia in a British population
22991974 This observation indicates a possible association of HLA-DRB1*01 with Dupuytren disease, but further studies are needed for confirmation.
22991420 Upon stratification analysis in search for a synergistic effect in sarcoidosis given the extensive linkage disequilibrium between BTNL2 rs2076530_A and HLA-DRB1*08:03; the risk-bearing allele of these two loci interact negatively.
22938381 we found the genotype HLA-DQB1*02:02, 03:01 to be significantly decreased and the allele HLA-DRB1*11:04 to be significantly increased among recurrent spontaneous abortions patients.
22935200 Elderly-onset rheumatoid arthritis is characterised by a different clinical presentation and HLA-DRB1 alleles with respect to young-onset rheumatoid arthritis.
22913598 The distribution of DRB1-DQB1 haplotypes and their association with onset-related characteristics of autoimmune diabetes varies across major racial/ethnic groups in the USA
22912672 a specific interaction between the HLA-DRB1*04 gene and smoking is associated with a high cardiovascular risk status
22898764 The (DR1/10)-DQB1*05:01 haplotype and the (DR1/10)-DQB1*05:01/DRB1*04:01-DQB1*03:02 genotype are independently associated with cardiovascular events and death in Finnish type 1 diabetic patients.
22893315 HLA-DRB1*04 and HLA-DRB1*13 alleles are associated with vascular events and an antiphospholipid positive immune-phenotype in systemic lupus erythematosus. Results demonstrate that a subset of SLE patients is genetically disposed to vascular vulnerability.
22892251 HLA-DRB1*04 and DRB1 *17 (03) may contribute to the Lyme borreliosis development in Latvian population.
22889831 Data indicate that 25 +/- 1.3% of CD74 and 17 +/- 0.3% of HLA-DR are colocalized.
22886382 HLA-DRB1*0101/*0405 is associated with susceptibility to anti-MDA-5 antibody-positive dermatomyositis in the Japanese population.
22868506 HLA-DRB1*14 may be associated with susceptibility to Acute lymphocytic leukemia acquisition among the Jiangsu Han population.
22863772 HLA class II DRB1 polymorphisms are involved in the genetic susceptibility to cervical cancer in Tunisian women.
22862152 The presence of DQB1*06:02 and not DRB1*15:01 was associated with narcolepsy in Chinese patients. Also, DRB1*15:01 has no effect on narcolepsy susceptibility in the absence of DQB1*06:02.
22860026 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
22848563 a role of VDREs in the promoter region of the DRB1 gene in susceptibility to MS carried by DRB1* alleles in Sardinian patients
22808111 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
22807207 we found an association with rs660895 within the HLA-DRB1 gene, which encodes the most polymorphic HLA-DR chain
22803655 HLA-DRB1 11 antigens elicit protective effect in the development of severe liver damage in Brazilian patients with chronic hepatitis C virus infection.
22781039 HLA-DRB1 allele polymorphisms are linked to a family history of cervical cancer in Uyghur women.
22733780 analysis of the HLA-DO/HLA-DM complex by FRET and mutagenesis
22731780 The associations between HLA-DRB1 alleles and Taiwanese children with Grave's disease by both case-control and family-based studies, were investigated.
22701553 Presence of 4 alleles of HLA-DRB in severe acute-kidney-injury patients seems associated with a lower need of renal replacement therapy.
22661643 This study provides the most comprehensive picture to date of how HLA-DRB1 shared epitope, PTPN22 and smoking are associated with the presence of specific antibodies reactivities rather than anti-citrullinated peptide levels.
22649493 HLA-DRB1*04 alleles were associated with high frequency of antibody responses to five out of nine Plasmodium vivax Merozoite Surface Protein-1 (MSP-1), MSP-3alpha and MSP-9 recombinant proteins tested in Rondonia State, Brazil.
22633068 epistatic interactions at the HLA-DRB1 locus contribute both to disease susceptibility and to the clinical phenotype in sporadic inclusion body myositis
22595829 In ANCA-associated vasculitis patients, DRB1*0405 might be an independent risk factor for the poor response to treatment and the deterioration of renal function.
22594481 One hundred and twenty healthy individuals from Vojvodina, northern Serbia, were studied for 18 of the HLA-DRB1 and HLA-DQB1 loci.
22590574 important new information concerning the susceptibility of HLA alleles in Caucasian MG, with highlights on DRB1*15:01 as being a major risk allele in LOMG.
22588649 The study suggests that HLA-DRB1*1501 and HLA-DQB1*0301 may influence the immune response to specific tumor and HPV-encoded epitopes and affect the risk of Kazakh esophageal squamous cell carcinoma in XinJiang, China.
22580214 HLA-DRB1*15 allele predisposes the Mexican mestizo to the development of aplastic anemia.
22578019 HLA-DRB1*04 was significantly associated with primary IgAN in Chinese population. This result implies that HLA-DRB1 gene plays a major role in primary IgAN
22573116 specifically support the role of classical HLA-DRB1 and DPB1 genes and alleles in susceptibility to primary biliary cirrhosis
22572536 The frequencies of DRB1*09:01 was significantly higher and the frequencies of DRB1*03:01 and DRB1*11:01 were significantly lower in the severe aplastic anemia group compared with those in the control group.
22564118 A meta-analysis suggest that DRB1*04, DRB1*08 and DRB1*14 are statistically significant susceptibility factors for pemphigus vulgaris.
22554526 there was a negative correlation between anti-nuclear antibodies and anti-Ro52, and carriage of HLA-DRB1*1301 in sporadic inclusion body myositis
22537824 The HLA-DRB1*04:05 allele was associated with increased risk of anti-citrullinated protein antibody-positive rheumatoid arthritis in Malaysians.
22523259 These data show that symptomatic Sindbis alphavirus infection infection is associated with the HLA system and that autoantibody titers are elevated in patients 3 years postinfection.
22521184 The data demonstrated a new HLA-myasthenia gravis predisposition with DRB1*04.
22509268 association of specific, independent DRB1*-DQB1* haplotypes confers susceptibility or resistance to multiple sclerosis
22504415 The HLA residues A-S(77), A-R(114) and DRbetaN(37) in combination with pulmonary tuberculosis antigenic elements possibly modulate T-cell responses against Mycobacterium tuberculosis that lead to either protection or susceptibility.
22499074 The HLA-DRB1*140101 allele may be potentially associated with increased risk of hepatocellular carcinoma development in chronic hepatitis b patients.
22494469 DRB1 and DQB1 loci are associated with type 1 diabetes mellitus in Iranians.
22487840 Respectively 18, 33 and 13 alleles were observed at HLA-A, B and DRB1 loci.
22461888 Data suggest that risk from the MHC class II transactivator (CIITA) locus is independent of the major risk for rheumatoid arthritis from HLA-DRB1 SE alleles, given that no significant interaction between rs3087456 and shared epitope alleles was observed.
22448298 The frequencies of HLA-DRB1*01 and HLA-B*14:02 were significantly lower in Chagas disease patients suffering from megacolon as well as in those with ECG alteration and/or.
22404765 Allelic variations at the HLA-DRB1 locus may influence multiple sclerosis disease severity.
22391763 By using a prospective study design, we demonstrated the protective effect of the DRB1*1302 allele against progression to CIN3 among Japanese women with low-grade squamous intraepithelial lesion.
22370504 HLA-DRB1*15 was found to be associated with multiple sclerosis in the Lithuanian population.
22367481 The frequency of LA-DRB1*03 in the CHB patient group was significantly higher compared to that in the asymptomatic hepatitis B carrier patients.
22363536 study concludes that the diverse DRB1*03:01-containing haplotypes contribute with different risk to multiple sclerosis susceptibility; the ancestral haplotype 18.2 causes the highest risk and affects only individuals showing oligoclonal IgM bands against myelin lipids
22357454 Breast cancer patients with HLA-DQA1 genotype have higher alanine aminotransferase (ALT) elevation, whereas the HLA-negative cases hve a higher incidence of Gilbert's syndrome.
22349877 there is a trend of positive association of HLA-DRB1*04 and HLA-DRB1*10 with rheumatoid arthritis and significant associations with the disease severity in the south Tunisian population
22339947 Data indicate that anti-citrullinated fibronectin peptide antibodies are associated with HLA-DRB1 shared epitope alleles.
22311500 HLA-DRB1*12:01:01 was more prevalent than HLA-DRB1*12:10 in the HLA-DRB1*12:01:01G group, and HLA-DRB1*14:54 was the dominant allele for HLA-DRB1*14:01:01G.
22310618 There was little correlation between HLA sensitization and HLA alleles of oneself. High frequency alleles and the specificity of high-frequency HLA antibodies were not consistent.
22310063 HLA-DRB1*01--related haplotype associates with ST-elevation myocardial infarction, possibly though increased inflammation.
22308705 Molecular genetic studies established the association of DRB1*07, DQB1*0.9, DQB1*02 specificities with the increased risk of cystic echinococcosis in children.
22307773 Our data indicate that HLA-DRB1*15 may promote the production of high anti-citrullinated protein antibodies levels.
22289814 Early peak seroconversion incidence was most evident in children with high-risk HLA DR3/4-DQ8 or DR4/4-DQ8 genotypes
22289117 Ultraviolet radiation exposure and vitamin D seem to affect risk of multiple sclerosis in adults independently of HLA-DRB1*15 status.
22286648 roles of the HLA-G molecule in the immune system and in several rheumatologic diseases, such as systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and others
22286218 Three amino acid positions (11, 71 and 74) in HLA-DRbeta1 and single-amino-acid polymorphisms in HLA-B (position 9) and HLA-DPbeta1 (position 9), all located in peptide-binding grooves, almost completely explain MHC association to rheumatoid arthritis risk.
22284614 HLA-DRB1*11 may be an immune response-related genetic factor that improve the development of a sustained virological response in patients chronically infected by the HCV-1 genotype and treated with pegylated interferon-alpha and ribavirin
22244918 genetic polymorphism is associated with myelodysplastic syndrome in Greece
22234791 This study indicates a putative association of HLA-DRB1 with moyamoya angiopathy in Caucasian patients.
22233603 We show HLA-DRB1*09:01 was the strongest determinant for lower anti-citrullinated peptide antibody in rheumatoid arthritis.
22224635 These results show a significant association of the homozygous HLA-DRB1*07 genotype with ulcerative colitis and Chron's diease.
22219324 vitamin D receptor polymorphisms are present in T2DM, and correlate with HLA DRB1*04 and with immunologic and metabolic parameters
22204478 Two single nucleotide polymorphisms (SNPs) in HLA-DRB1*14 gene are found in North Indian patients with rheumatic heart disease.
22196942 Study characterized the peptide-binding properties of HLA-DRB1*1201 (DR1201).
22186711 Smoking appears to be associated with an increased risk of possession of anti-Jo-1 in HLA-DRB1*03-positive idiopathic inflammatory myopathy cases.
22170232 these data demonstrate that variation at HLA-DRbeta1, amino acid 11 in the P6 pocket of the HLA-DR complex antigen binding cleft is a major determinant of chromosome 6p association with UC.
22166691 HLA DRbeta1*04 was expressed with significantly increased frequency in patients with rheumatoid arthritis
22156484 The HLA-DRB1*010101 allele is closely associated with poor virological response to initial lamivudine therapy in Chronic Hepatitis B patients.
22127897 Report association of HLA-DRB1*15:01 with multiple sclerosis is female specific.
22122841 Data show that HLA-DRB1*12:02:01 plays a protective role against coronary artery disease (CAD) in southern Han Chinese, especially in females.
22121859 The results of this study suggested a positive association between DRB1*03 (DRB1*030101, DRB1*030102) with schizophrenia and a negative association of DRB1*06 with schizophrenia in Saudi Arabian patients.
22119882 Data show 3 sequenced new HLA-DRB1 variants officially named DRB1*03:05:03, DRB1*11:10:02, and DRB1*14:86.
22112985 There were no significant associations between the presence of HLA DRB1*1501 allele and the clinical symptoms, course of disease, or disability score, in multiple sclerosis.
22106694 increases by a factor of 5.68 for every unit increase in the number of DRB1*0301 allele (P < 0.001)
22096508 Results suggest that non-Hodgkin lymphoma risk factors vary in their association based on HLA-DRB1*01:01 and AH 8.1 status.
22094856 HLA-DRB1 amino acids in pocket 4 are important for the binding of citrullinated autoantigens and susceptibility to rheumatoid arthritis.
22084083 Interaction with HLA-DM is driven by a conformational change of the MHC II protein in the region of the alpha-subunit 310 helix and adjacent extended strand region.
22074999 Data show that the most prevalent alleles at the four loci in the black population were A*30:01, B*58:02, C*06:02, and DRB1*13:01 and in the Caucasian population were A*02:01:01, B*07:02:01, C*07:01, and DRB1*03:01.
22074998 Data show that the susceptibility allele for sarcoidosis was HLA-DRB1*15:01, the protective allele was HLA-DRB1*01:01, and HLA-DRB1*03:01 was associated with resolving disease when compared with the persistent group.
22068554 genetic association studies in a Brazilian population: In a multiethnic population of patients with type 1 diabetes and their first degree relatives, pancreatic autoantibodies are associated with genetic polymorphisms of HLA-DRB1 (but not PTPN22).
22057263 This study found HLA-DBR1 0901 in patients with familial myasthenia gravis.
22042692 Data indicate that the presence of an HLA-B antigen (Ag) mismatch was significantly associated with a lower overall survival rate than an HLA-DR Ag mismatch because of an increased risk of treatment-related mortality.
22028790 the promoter and 3'-UTR of HLA-DRB1 may antagonistically regulate the gene expression, which may be subjected to stabilizing selection
21982422 HLA matching at HLA A, B, C, and DRB1 should be done to minimize mortality risks after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome.
21978430 Rheumatoid arthritis (RA) susceptibility allele, HLA-DRB1, investigated according to revised criteria for the classification of RA, is significantly increased in South African RA patients.
21964432 Several different DRB1* alleles may be involved in the etiopathogenesis of the disease by presenting an overlapping set of ocular peptides to the T cells, which may trigger the autoimmune response seen in the Vogt-Koyanagi-Harada syndrome patients.
21955839 genetic association studies in prepubertal boys in Western Ukraine: Allele frequencies of HLA-DRB1 did not differ between boys with familial cryptorchidism (and anti-sperm antibodies) and control boys except in HLA-DRB1*11 frequency.
21952999 In a sample of Brazilian patients with RA, most of whom of mixed heritage, HLA-DRB1 SE+ alleles were associated with susceptibility to disease and presence of anti-citrullinated peptide antibodies
21929573 Frequency of HLA-A, -B and -DRB1 specificities and haplotypic associations in the population of Castilla y Leon (northwest-central Spain).
21924912 HLA-DRB1(*)09 might be positively associated and DRB1(*)08 negatively associated with myesthenia gravis in the northern Han Chinese population.
21922073 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
21911185 analysis performed stratifying by the presence of HPV-16 infection showed that the frequency of HLA-DRB1 *04:07 (OR = 2.71) was increased in CC patients infected with HPV-16, confirming that the HLA association is HPV dependent
21908482 frequency of HLA-DQB1*0402 allele was increased in Neuromyelitis optica
21902584 The frequency of HLA-DRB1*15 in NVP-tolerant cases was significant higher than that in NVP HSR cases.
21900604 Data provide an atomic-level description of the CD4-binding site on MHC class II and reveals how CD4 recognizes highly polymorphic HLA-DR, -DP, and -DQ molecules by targeting invariant residues in their alpha2 and beta2 domains.
21898163 Molecular Dynamics simulations of the MuBetaRho 83-99 (Phe91) and MuBetaRho 83-99 (Tyr91) peptide analogues in complex with HLA-DR2 (DRA, DRB1*1501) and T-cell receptors were performed.
21891926 These data indicate that the polymorphisms in HLA-DRB1 may influence the risk of ACI in the North Han population of China.
21888287 HLA-DRBI*02 & DRBI*03 were significantly associated with the probability for developing cancer independent of family history of rheumatoid arthritis & cancer, recurrent sore throat, alopecia, & clinical activity of rheumatoid arthritis.
21881596 HLA-DRB1 shared epitope alleles show heterogeneity in rheumatoid arthritis susceptibility
21873689 in this large-scale association study multiple HLA-DRB1 alleles and diplotypes were found to be associated with susceptibility to, or protection against, ACPA-negative rheumatoid arthritis
21851420 HLA-DRB1 showed negative correlations with the free-testosterone concentration both in total subjects and polycystic ovarian syndrome patients.
21833019 Our studies have identified three specific alleles, HLA-A*33:01, HLA-B*44:03, and HLA-DRB1*07:01, to be significantly increased in vitiligo patients as compared with controls in both the initial study on North Indians.
21833018 HLA-DRB1*15:03 allelic frequencies were 50% for African epidermolysis bullosa acquisita patients, significantly higher than that of the control population.
21820153 Unlike in their adult counterpart, the expression of matrix metalloproteinase 2 or the loss of HLA class II antigens does not discriminate between benign and malignant tumors in children.
21816760 There appears to be a relationship between polymorphisms in the VDR and the risk of MS, which is potentially modified by HLA-DRB1*1501.
21816002 The frequencies of human leucocyte antigen (HLA)-A, -B and -DRB1 alleles and haplotypes were statistically analysed among 3238 donors from Chinese Marrow Donor Program (CMDP) Jiangsu Branch.
21809595 To review susceptibility gene of Shuanghuanglian allergen injection based on a theory of genetic fingerprints, to make sure about the relationship the major allergen of Shuanghuanglian injection and HLA-DRB gene polymorphism [review article]
21806423 no association with idiopathic thrombocytopenic purpura in the North Indian population
21796887 Regarding the HLA class II alleles, a statistically significant increase in frequency of HLA-DRB1*03 and DQB1*0201 allele was found among patients with acute sarcoidosis in comparison to controls
21778700 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
21762745 Susceptibility to aplastic anemia is associated with HLA-DRB1*1501 in an aboriginal population in Sabah, Malaysia.
21751159 the HLA-DRB1*15 allele is associated with pulmonary tuberculosis . The HLA-DRB1 promoter region sequences had no association with the development of pulmonary tuberculosis
21748712 Data show that Caucasian patients with neuromyelitis optica and multiple sclerosis have a different HLA-DRB1 allelic distribution.
21744463 DRB1*0301-DQA1*0501-DQB1*0201 was more frequent in type 1 diabetes patients with associated automimmune diseases
21741664 HLA-DRB1*1501 and HLA-DQB1*0602 alleles are more frequently detected in Greek patients with initial multiple sclerosis symptoms from the brainstem or the cerebellum.
21739420 genetic variants in the HLA-DRB1 gene significantly increase the susceptibility to Kashin-Beck disease in the Tibetan population.
21732917 Characterization of 236 novel alleles at the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci
21726205 DRB1*15:02:08 is a novel HLA-DRB1 allele
21720852 Investigated the association between HLA-DRB1,-DQA1 and -DQB1 and breast cancer in Iranian women. Two groups were studied, group 1 includes patients 40 years or younger and group 2 include patients over 40 years.
21716163 The findings suggest HLA-DRB1 gene might be associated with autism in Han Chinese.
21712058 Data show that a total of 49, 86, 50, 63, and 24 HLA-A, -B, -C, -DRB1, and -DQB1 alleles were observed.
21709571 The HLA-DRB1*1401 allele might be a risk factor for idiopathic dilated cardiomyopathy and HLA-DRB1*0901 and HLA-DRB1*0301 might protect humans from idiopathic dilated cardiomyopathy.
21699788 HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
21676191 DRB1*04:92 has one nucleotide change from DRB1*04:07:01 at codon 207 in exon 4, producing an amino acid replacement (V > M) in the transmembrane domain
21659045 This study will serve as a reference for further anthropological studies, as well as studies of HLA and disease associations in the Moroccan population
21653833 A mutated myelin oligodendrocyte glycoprotein (MOG) peptide [MOG97-109] enables detection of a greater frequency of MOG97-109-reactive T cells in multiple sclerosis patients bearing the HLA-DRB1*0401 allele compared to healthy controls.
21652028 these data suggest that the variation in HLA-DRB1/DQB1 alleles and haplotypes could be a genetic factor involved in the susceptibility of autoimmune polyglandular syndromes.
21646624 Herpes simplex virus-1 is associated with an increased risk of multiple sclerosis in children without an HLA-DRB1*15 allele, whereas the effect is reversed in those who are DRB1*15-positive.
21644227 Compared with normal controls, the frequency of HLA-DRB1*15 was significantly increased in the myelodysplastic syndrome group and aplastic anemia group
21621859 HLA DRB1*1501 positivity is associated with increased brain inflammatory processes at first clinical onset of multiple sclerosis demyelinating event.
21617122 DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans.
21614018 These findings point to the importance of non-HLA genes in determining RA risk in a population with a high frequency of disease predisposing HLA-DRB1 alleles.
21599852 We found an increased frequency of the HLA-DRB1*11 allele in patients with lepromatous leprosy compared with healthy controls
21598828 In our population, the SE (QRRAA) expressed in DRBI*04 alleles is related to the susceptibility to RA but it is not involved in RA severity in Tunisia
21593777 HLA-DRB1*07:01 was strongly associated with chronicity.
21569485 The combined presence of DRB1*1501 and absence of DPB1*0401 might have an even higher risk to anti-GBM disease than HLA-DRB1*1501 alone.
21557256 findings show the HLA-DRB1(*) 04 allele might be related to angiotensin AT(1) autoantibody production in hypertensive subjects
21554253 analysis of HLA-DRB1*04:02, DRB1*08:04 and DRB1*14 alleles associated to pemphigus vulgaris in southeastern Brazilian population
21535077 The results confirmed previous reports of the association of DRB1*1 1 and DQB1*0 3 with protection from chronic HCV infection, but did not confirm their association with protection from severe fi brosis cirrhosis.
21501120 HLA-A, HLA-B, and HLA-DRB1 allele distribution in a large Armenian population sample.
21497601 HLA tissue-typing of these lupus patients revealed a prominent subgroup (~30%) of patients possessing the HLA DRB1*1503 allele
21484216 HLA-DRB1*02 is protective for type 2 diabetes, probably by enhancing self tolerance, thereby protecting against the autoimmune-mediated reduction of insulin secretion.
21447263 Patients with Wolfram syndrome have a different profile of the HLA antigens with the presence of DR2, DQw1 and DRB3/4 allele and are negative for diabetes-related autoantibodies
21431378 Beneficial effect of vitamin D on multiple sclerosis risk may be attenuated in individuals carrying the HLA-DR15 risk allele assessed by genotyping; a single polymorphism strongly correlates with the HLA-DRB1 1501 risk haplotype.
21429451 In Egyptian Hepatitis C virus-infected children, the most frequent HLA-DRB1 alleles were DRB1*03, DRB1*04 and DRB1*13, while the frequency of DRB1*15 was reduced compared with control subjects. DRB1*03 was associated with reduced platelet count.
21422655 The data suggest that the DRB1FNx0110 allele is a risk factor and DRB1FNx0103 is protective for rheumatoid arthritis in this population.
21422625 Report HLA-DRB1 genetic polymorphisms are involved in determining susceptibility to diabetes mellitus type 1 in a Lebanese population.
21418440 There is an association between HLA-DRB1 alleles and the presence of oligoclonal immunoglobulin G (IgG) bands in cerebrospinal fluid in a Spanish population with multiple sclerosis.
21417892 The researchers evaluated the HLA-DRB1 locus and found that current Aleut populations are closer genetically to Europeans than Eskimos and Native Americans.
21413052 Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket influence genetic susceptibility to primary sclerosing cholangitis.
21411354 the allele HLA-DRB1*14 was found to be associated with susceptibility to syphilis in the Chinese population
21396892 An HLA-DRB1*1501 allele and the TGF-alpha G/A polymorphism are associated with the risk of multiple sclerosis in an Iranian population.
21395562 analysis of two novel HLA class II alleles, DRB1*11:96 and DQB1*02:01:03, identified in Koreans
21388361 The new allele DRB1*13:99 showed one nucleotide difference with DRB1*13:02:01 at codon 51 (ACG/AAG).
21388356 Analysis of the complete cDNA sequences of HLA-DRB1 alleles with group-specific amplification primers in the Chinese Han population.
21373184 The allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis.
21360493 These results indicate that patients who genotypically lack the shared epitope can acquire it as persistent microchimerism from fetal-maternal cell exchange, suggesting that SE-encoding microchimerism could be a risk factor for rheumatoid arthritis.
21358010 Atherogenic effect of the LDL- cholesterol may be dampened by HDL-cholesterol through anti inflammatory cytokine IL-10 and HLA-DR16.
21354458 genetic polymorphism is associated with antineutrophil cytoplasmic antibody-associated systemic vasculitis in Chinese patients
21342137 Systemic lupus erythematosus is associated with HLA-A, HLA-B, and HLA-DRB1 alleles in Pakistani population.
21340025 The lack of strong associations of (chronic cerebrospinal vascular insufficiency)CCSVI with HLA DRB1*1501 suggests that the role of the underlying associations of CCSVI in multiple sclerosis should be interpreted with caution.
21325036 HLA-DQ and -DR may have a role in recurrent miscarriages among South Indian women
21316924 there is an association between CTLA4 SNP (49 G allele) and HLA-DRB1*08 with psoriasis in Japanese psoriasis vulgaris patients
21303861 The findings of this study indicated that Smoking and human HLA-drb1 interact to increase the risk for multiple sclerosis.
21299892 HLA-DRB1 was found to have bimodal expression in human skeletal muscle tissue.
21292329 DQB1*0602 positivity is associated with both a shift in EEG power spectrum to faster frequencies during REM sleep and a diminution of restedness given the same sleep quantity.
21288988 The HLA-DRB1*15 allele confers increased risk of pediatric-onset multiple sclerosis in children with acquired demyelination.
21280007 DRB1*0407 and *1304 are independent risk factors, beyond the known clinical correlates, for the development of scleroderma renal crisis.
21276381 HLA DRB1*13 is a genetic marker possibly associated with increased risk of developing NIDDM in a Pakistani population.
21270202 Interferon-associated type 1 diabetes is characterized clinically by high titers of GAD65 antibodies and preserved beta-cell function, and genetically by addition of HLA-A*2402to DRB1*1302-DQA1*0102-DQB1*0604
21251479 No genetic marker clearly indicative of disease susceptibility or resistance was identified in this study. However, HLA-DRB1*14 was more frequent in TB patients
21246357 Results of this study indicate that HLA-DRB1*01, *04, and *09 alleles were associated with rheumatoid arthritis (RA), and HLA-DRB1*13 was protective allele against RA.
21241376 The DRB1*07 showed significant association with vitiligo in the study population
21186201 findings indicate that the primary association was with DPbetaE69 for beryllium disease and beryllium toxicity and that the other residues found to be associated did not by themselves confer an additional risk beyond and above that of the DPbetaE69 residue.
21179106 an association between HLA-DRB1(*)04:05 and polyarticular Juvenile idiopathic arthritis
21172035 DRB1*07 and DRB1*12 were significantly associated with the risk of hepatocellular carcinoma in the whole populations; DRB1*07, DRB1*12 and DRB1*15 alleles significantly increased the risk of hepatocellular carcinoma in Asians
21149397 Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition.
21091360 there were significant associations of the haplotype HLA-DQB1*0301-DRB1*04 with the prevalence of auto-antibodies against alpha(1)-adrenergic receptors in hypertensive patients
21087494 show that the GSTM1-null genotype, a common genetic variant, exerts significant additive interaction with HLA-DRB1 shared epitope on the risk of anticitrullinated protein antibody positivity in rheumatoid arthritis
21087494 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
21087485 Observational study of gene-disease association. (HuGE Navigator)
21085635 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
21079793 Findings could be valuable for HLA matching in clinical bone marrow transplantation, HLA-linked disease-association studies, population genetics, human identification and paternity tests in forensic sciences.
21079793 Observational study of genotype prevalence. (HuGE Navigator)
21075156 Observational study of gene-disease association. (HuGE Navigator)
21074862 Observational study of gene-disease association. (HuGE Navigator)
21072187 Observational study of gene-disease association. (HuGE Navigator)
21067577 It is concluded that HLA-DRB1*13 may be a susceptibility allele for the occurrence of autoimmune hepatitis in our population. HLA-DRB1*07 and HLA-DRB1*15 may be susceptibility alleles for occurrence of autoimmune hepatitis type 2.
21067577 Observational study of gene-disease association. (HuGE Navigator)
21067287 Observational study of gene-disease association. (HuGE Navigator)
21063024 Data show that CD14(+)HLA-DR(low/-) monocytes are a major and multifactorial contributor to systemic immunosuppression in NHL.
21062236 there were no significant HLA-DRB1 alleles associated with Graves' disease in Koreans
21062236 Observational study of gene-disease association. (HuGE Navigator)
21059899 Observational study of gene-disease association. (HuGE Navigator)
21059595 The incidence of HLA-DRB1*0102 is increased in sudden-onset bilateral anterior uveitis, as seen in patients with tubulointerstitial nephritis and uveitis. The same allele does not appear to occur in increased frequency in patients with isolated TIN.
21059595 Observational study of gene-disease association. (HuGE Navigator)
21049023 Observational study of gene-disease association. (HuGE Navigator)
21040492 Observational study of gene-disease association. (HuGE Navigator)
21033293 The occurence of these HLA alleles is significantly higher in T1D patients than in LADA and identifies patients of high risk and requirement of insulin therapy.
21033293 Observational study of gene-disease association. (HuGE Navigator)
21031025 HLA-DRB1 and HLA-DQB1 polymorphisms have no significant effect on the development of Normal tension glaucoma in Japanese patients
21031025 Observational study of gene-disease association. (HuGE Navigator)
21029659 The distribution patterns of HLA-DRB1 and -DQB1 alleles among young women with cervical squamous cell carcinoma are different from those of older women.
21029659 Observational study of gene-disease association. (HuGE Navigator)
20977916 Observational study of gene-disease association. (HuGE Navigator)
20974205 Observational study of gene-disease association. (HuGE Navigator)
20972469 Observational study of gene-disease association. (HuGE Navigator)
20970669 Observational study of gene-disease association. (HuGE Navigator)
20966625 Observational study of gene-disease association. (HuGE Navigator)
20937338 Observational study of gene-disease association. (HuGE Navigator)
20933106 Observational study of gene-disease association. (HuGE Navigator)
20931685 Observational study of gene-disease association. (HuGE Navigator)
20923327 Observational study of genotype prevalence. (HuGE Navigator)
20923326 Observational study of genotype prevalence. (HuGE Navigator)
20919945 In this study of North Italian patients affected with EHOA, the HLA-DRB1*07 allele was found to be associated with both the development and greater severity of the disease.
20888281 Observational study of gene-disease association. (HuGE Navigator)
20884011 study has provided novel data on the spectrum of MS lesions in the spinal cord during life and has also provided evidence that the HLA-DRB1 genotype may play a role in determining the severity and extent of spinal cord involvement and type of lesions.
20884011 Observational study of gene-disease association. (HuGE Navigator)
20876154 Letter/Case Report: Report association between HLA CRB1*1501, vitamin D deficiency, and multiple sclerosis in a patient with membranous glomerulopathy.
20861181 Comparison of the HLA-DRB1 and DQB1 distribution in neuromyelitis and multiple sclerosis in an Afro-Caribbean population shows important differences.
20861181 Observational study of gene-disease association. (HuGE Navigator)
20858521 These results show a strong association of HLA-DQB1*0201/0302 and DRB1*03/04 with type 1 diabetes.
20858521 Observational study of gene-disease association. (HuGE Navigator)
20854863 Observational study of gene-disease association. (HuGE Navigator)
20851016 Observational study of gene-disease association. (HuGE Navigator)
20850383 Observational study of gene-disease association. (HuGE Navigator)
20849588 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20843162 Observational study of gene-disease association. (HuGE Navigator)
20842443 CHD in Chinese population is strongly associated with HLA-DRB1*01 and DRB1*04 haplotypes, and formation of CD4(+)CD28(null) T cells was related to HLA-DRB1*01, DRB1*04, and DRB1*15 alleles.
20842443 Observational study of gene-disease association. (HuGE Navigator)
20837527 Observational study of gene-disease association. (HuGE Navigator)
20825955 Observational study of gene-disease association. (HuGE Navigator)
20810130 Our results show the importance of epistatic interactions among the HLA-DRB1 alleles, modifying the risk for multiple sclerosis as well as its clinical severity
20810130 Observational study of gene-disease association. (HuGE Navigator)
20800921 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20798335 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20797713 We found an association of CCL21 (rs2812378) and HLA-DRB1 (rs660895) with moderate to severe endometriosis
20797713 Observational study of gene-disease association. (HuGE Navigator)
20739684 Observational study of gene-disease association. (HuGE Navigator)
20736246 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20735759 the role of the HLA DRB1*03 in asthma susceptibility is independent of ancestral-haplotype-mediated linkage disequilibrium.
20735759 Observational study of gene-disease association. (HuGE Navigator)
20725783 Observational study of gene-disease association. (HuGE Navigator)
20723328 Observational study of gene-disease association. (HuGE Navigator)
20722010 The risk of RA attributable to smoking is limited to African Americans with more than 10 pack-years of exposure and is more pronounced among individuals positive for the HLA-DRB1 SE.
20722010 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20719952 individuals with both HLA-DRB1*13 and HLA-DQB1*06 had highly polyfunctional mucosal CD4+ T cells compared to individuals with HLA-DQB1*06 alone or other class II alleles
20719952 Observational study of gene-disease association. (HuGE Navigator)
20711174 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
20694011 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
20692483 Observational study of gene-disease association. (HuGE Navigator)
20691532 Observational study of gene-disease association. (HuGE Navigator)
20686866 Observational study of gene-disease association. (HuGE Navigator)
20685768 Our results have shown that the G allele at the interleukin 6 promoter polymorphism may be associated with development of multiple sclerosis in this population, and may be strengthened by HLA-DRB1*1501
20685768 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20685690 Observational study of gene-disease association. (HuGE Navigator)
20684489 Observational study of gene-disease association. (HuGE Navigator)
20678810 Observational study of gene-disease association. (HuGE Navigator)
20671941 Observational study of gene-disease association. (HuGE Navigator)
20670354 Observational study of genotype prevalence. (HuGE Navigator)
20670332 Observational study of genotype prevalence. (HuGE Navigator)
20668555 Study found association between extended LTA, TNF, LST1 and HLA gene haplotypes and rubella vaccine-induced immunity.
20668555 Observational study of gene-disease association. (HuGE Navigator)
20666704 Observational study of genotype prevalence. (HuGE Navigator)
20639878 Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20639266 Observational study of gene-disease association. (HuGE Navigator)
20637045 Observational study of genotype prevalence. (HuGE Navigator)
20634196 Maternal transmission of HLA-DRB1 to affected multiple sclerosis daughters was more distorted than to affected sons.
20634196 Observational study of gene-disease association. (HuGE Navigator)
20631027 Observational study of gene-disease association. (HuGE Navigator)
20629714 HLA-DRB1*15 is associated with multiple sclerosis
20629714 Observational study of gene-disease association. (HuGE Navigator)
20627832 Observational study of gene-disease association. (HuGE Navigator)
20617178 Observational study of gene-disease association. (HuGE Navigator)
20606439 Observational study of gene-disease association. (HuGE Navigator)
20603497 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20603341 HLA DRB1-DQB1 genotypes are are significant predictors for disease progression in latent autoimmune diabetes of adults.
20603341 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20600444 Observational study of genotype prevalence. (HuGE Navigator)
20595679 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
20595243 Observational study of gene-disease association and genetic testing. (HuGE Navigator)
20594918 The haplotype containing both the HLA-DRB1*1501 and IL-2 -330 T alleles showed a higher frequency in Iranian multiple sclerosis patients than in the general population.
20594918 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20593013 Observational study of gene-disease association. (HuGE Navigator)
20592276 When HLA-DRB1-shared epitope-activated dendritic cells are cocultured with CD4+ T cells, the differentiation of Foxp3+ T regulatory cells is suppressed, whereas T helper type (Th)17 cells are expanded.
20591987 Multiple sclerosis and neuromyelitis optica differ in their associations with DRB1*1501.
20591987 Observational study of gene-disease association. (HuGE Navigator)
20586801 Observational study of gene-disease association. (HuGE Navigator)
20584722 Observational study of gene-disease association. (HuGE Navigator)
20580995 Observational study of gene-disease association. (HuGE Navigator)
20580654 Observational study of gene-disease association. (HuGE Navigator)
20569042 an association was found between some HLA-DRB1 allele combinations and type 1 diabetes while some allele combinations were protective
20569042 Observational study of gene-disease association. (HuGE Navigator)
20561992 Meta-analysis of gene-disease association. (HuGE Navigator)
20560812 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20559009 HLA-DRB1*04 allele is prevalent in Polish patients with chronic spontaneous urticaria
20559009 Observational study of gene-disease association. (HuGE Navigator)
20550778 Observational study of gene-disease association. (HuGE Navigator)
20549830 Observational study of gene-disease association. (HuGE Navigator)
20547426 Observational study of gene-disease association. (HuGE Navigator)
20542071 The presence of the MSH5 85F allele marks the subgroup of DRB1*0102 haplotypes carrying susceptibility for selective IgA deficiency. MSH5 polymorphisms per se are not predisposing factors.
20542071 Observational study of gene-disease association. (HuGE Navigator)
20541027 Observational study of gene-disease association. (HuGE Navigator)
20537664 Observational study of gene-disease association. (HuGE Navigator)
20537173 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20536993 Observational study of gene-disease association. (HuGE Navigator)
20536911 Observational study of gene-disease association. (HuGE Navigator)
20533289 Observational study of gene-disease association. (HuGE Navigator)
20522537 Observational study of gene-disease association. (HuGE Navigator)
20522202 Observational study of genotype prevalence. (HuGE Navigator)
20522201 an association between HLA-DRB1 alleles and susceptibility or resistance to keloids in Chinese Han individuals
20522201 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20518846 Observational study of genotype prevalence. (HuGE Navigator)
20518845 Observational study of genotype prevalence. (HuGE Navigator)
20510319 Data show that DRB1*0802-DQB1*0302 (DR8) onfers susceptibility to slow-onset T1D in the Japanese population.
20510319 Observational study of gene-disease association. (HuGE Navigator)
20507388 Observational study of gene-disease association. (HuGE Navigator)
20502044 Observational study of gene-disease association. (HuGE Navigator)
20497637 HLA-DRB1*08 may be the susceptible allele of juvenile idiopathic arthritis (JIA), while HLA-DRB1*12 may be the protective allele of JIA in Han children from Guangdong Province.
20497637 Observational study of gene-disease association. (HuGE Navigator)
20493227 Studies identified 51 A, 121 B, and 53 DRB1 alleles in Taiwanese group, and 17 A, 32 B, and 23 DRB1 alleles in Taiwanese aborigines, and findings may provide useful information in search for HLA-matched donors for patients.
20493227 Observational study of genotype prevalence. (HuGE Navigator)
20492599 Observational study of genotype prevalence. (HuGE Navigator)
20492596 Observational study of gene-disease association. (HuGE Navigator)
20486920 HLA-DQB1*03 may be protective of the development of Alternaria-sensitive severe asthma
20486920 Observational study of gene-disease association. (HuGE Navigator)
20478772 Observational study of gene-disease association. (HuGE Navigator)
20476860 Observational study of gene-disease association. (HuGE Navigator)
20466734 Observational study of gene-disease association. (HuGE Navigator)
20463743 Opposing effects of the HLA-DRB1*0301-DQB1*0201 haplotype on the risk for multiple sclerosis in Muslim vs. Christian Arab populations in Israel.
20463743 Observational study of gene-disease association. (HuGE Navigator)
20462916 Observational study of gene-disease association. (HuGE Navigator)
20462405 Observational study of genotype prevalence. (HuGE Navigator)
20449807 Observational study of gene-disease association. (HuGE Navigator)
20448347 HLA-A, -B and -DRB1 alleles and haplotypes are highly polymorphic in the Miao population, and are most similar to that of the South China population.
20448347 Observational study of genotype prevalence. (HuGE Navigator)
20444266 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20439292 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20438789 Results showed that in a Javanese population, HLA-B*1802 and HLADRB1* 1202 were the most promising candidate alleles for susceptibility and resistance to recurrent pulmonary tuberculosis, respectively.
20438789 Observational study of gene-disease association. (HuGE Navigator)
20437569 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20426625 HLA/KIR-longevity associations are population specific and affected by environment.
20426625 Observational study of gene-disease association. (HuGE Navigator)
20424860 Thus, this study has identified that carriers of HLA-DR16 are at high risk for cystic echinococcosis, so appropriate preventive measures and quick and careful treatment should be applied to those patients.
20424860 Observational study of gene-disease association. (HuGE Navigator)
20417641 determined the crystal structure of a phosphopeptide derived from melanoma antigen recognized by T cells-1 (pMART-1), selectively expressed by melanomas, in complex with HLA-DR1
20405713 Observational study of gene-disease association. (HuGE Navigator)
20403137 four polymorphic Alu insertion loci were in significant linkage disequilibrium and had a high percentage association with a variety of HLA-DRB1 or -DQB1 two-digit alleles
20403136 HLA-DRB1 short tandem repeat markers were genotyped in 85 individuals
20395221 Observational study of gene-disease association. (HuGE Navigator)
20394989 DNA methylation of CpG dinucleotides across HLA-DRB1*1501 and HLA-DRB5 does not determine whether patients manifest benign or malignant multiple sclerosis.
20392899 HLA-DRB1*04 was found to impart a significant protective advantage [Bonferroni-corrected P value (pc)=0.047] against hepatitis C virus infection.
20392899 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20387488 HLA-DRB1 * 1301 and 1302 is closely associated with the suseptibility to severe chronic hepatitis B.
20385791 Observational study of gene-disease association. (HuGE Navigator)
20383728 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20380523 Observational study of genotype prevalence. (HuGE Navigator)
20380521 confers susceptibility to juvenile systemic lupus erythematosus but is not associated with clinical presentations
20380521 Observational study of gene-disease association. (HuGE Navigator)
20375311 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20374297 Observational study of gene-disease association. (HuGE Navigator)
20371654 Observational study of gene-disease association. (HuGE Navigator)
20370905 HLA DRB1 alleles with the shared epitope are associated with production of antibodies against citrullinated proteins.
20370905 Observational study of gene-disease association. (HuGE Navigator)
20353806 In Taiwanese Chinese, a strong HLA-DRB1*0405 association with resistance to multibacillary leprosy was found, supporting results previously reported in the literature.
20353806 Observational study of gene-disease association. (HuGE Navigator)
20353580 Observational study of gene-disease association. (HuGE Navigator)
20352225 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20347497 Observational study of gene-disease association. (HuGE Navigator)
20346252 The profile of HLA-DRB1 alleles associations in Mexican with juvenile idiopathic arthritis were somewhat distinct from association typically found in Caucasians
20346252 Observational study of gene-disease association. (HuGE Navigator)
20345929 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20345872 Haplotype DRB1*0902-DQB1*030103(OR=10.65;P=0.06)was increased in HIV1 patients,while haplotypes DRB1*150101-DQB1*060101(OR=0.386,P<0.0001), DRB1*030101-DQB1*020101(OR=0.197,P=0.004) and DRB1*070101-DQB1*0202(OR=0.167,P=0.001) were decreased.
20345872 Observational study of gene-disease association. (HuGE Navigator)
20335276 Observational study of gene-disease association. (HuGE Navigator)
20335219 Observational study of gene-disease association. (HuGE Navigator)
20331476 CatG cleaves human leukocyte antigen (HLA)-DR in vitro. Cleavage occurred on the loop between fx1 and fx2 of the membrane-proximal beta2 domain. In vivo, however, the CatG cleavage site is sterically inaccessible or masked by associated molecules.
20309863 Observational study of gene-disease association. (HuGE Navigator)
20307907 Observational study of gene-disease association. (HuGE Navigator)
20303356 the HLA-DRB1*0405 allele appears to be an important risk factor for Autoimmune pancreatitis (AIP)on the HLA-DRB1*0405/DQB1*0401 haplotype.
20298583 Observational study of gene-disease association. (HuGE Navigator)
20237121 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20235791 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20233754 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20230525 Observational study of genotype prevalence. (HuGE Navigator)
20230522 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20225292 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20224785 Observational study of gene-disease association. (HuGE Navigator)
20221424 Observational study of gene-disease association. (HuGE Navigator)
20216938 The epitope S57-LLEQRRAA (67-74) in the third hypervariable region of the HLA-DRbeta1 molecule is the relevant susceptibility epitope.
20216938 Observational study of gene-disease association. (HuGE Navigator)
20214848 Observational study of gene-disease association. (HuGE Navigator)
20211854 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20210922 HLA-DRB1*1454 is the most common DRB1*14 allele among German Caucasians
20210922 Observational study of genotype prevalence. (HuGE Navigator)
20209134 MHC class II antigen processing and presentation is preserved in monocytes from HIV-infected individuals
20207784 HLA-DRB1*1501 was the strongest risk allele in both primary progressive MS and relapsing-remitting MS.
20207784 Observational study of gene-disease association. (HuGE Navigator)
20205319 Observational study of gene-disease association. (HuGE Navigator)
20196860 Observational study of gene-disease association. (HuGE Navigator)
20196826 Observational study of genotype prevalence. (HuGE Navigator)
20196825 Observational study of genotype prevalence. (HuGE Navigator)
20193583 Observational study of gene-disease association. (HuGE Navigator)
20193456 Kazakh patients with HLA-DRB1*1501, HLA-DQB1*0301, and HLA-DQB1* 0602 may be susceptible to esophageal squamous cell carcinoma.
20193456 Observational study of gene-disease association. (HuGE Navigator)
20193235 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20191588 Observational study of gene-disease association. (HuGE Navigator)
20191587 Observational study of gene-disease association. (HuGE Navigator)
20187937 Observational study of gene-disease association. (HuGE Navigator)
20179740 These data demonstrate a statistical interaction between HTR2A and HLA-DRB1 shared epitope alleles and colocalization of the product of these two genes in inflamed synovial tissue.
20179740 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20173784 Observational study of gene-disease association. (HuGE Navigator)
20170930 Observational study of gene-disease association. (HuGE Navigator)
20169624 Observational study of gene-disease association. (HuGE Navigator)
20164547 Observational study of gene-disease association. (HuGE Navigator)
20154067 Observational study of gene-disease association. (HuGE Navigator)
20150397 Observational study of gene-disease association. (HuGE Navigator)
20147981 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20145915 Observational study of gene-disease association. (HuGE Navigator)
20141578 Letter: Report HLA-DRB1*11 as a strong risk factor for acquired severe ADAMTS13 deficiency-related idiopathic thrombotic thrombocytopenic purpura in Caucasians.
20141578 Observational study of gene-disease association. (HuGE Navigator)
20112396 the combination of HLA-DRB1 shared epitope alleles and smoking is associated with rheumatoid arthritis susceptibility regardless of anti-CCP antibody or RF status
20112396 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20108780 Observational study of gene-disease association. (HuGE Navigator)
20105138 HLA class II molecule DRbeta1*0701 is identified as novel genetic risk factor for development of Guillain-Barre syndrome in patients with preceding infection.
20101097 Observational study of genetic testing. (HuGE Navigator)
20095337 Observational study of gene-disease association. (HuGE Navigator)
20090103 Observational study of gene-disease association. (HuGE Navigator)
20083660 Peptides in rotavirus VP7, similar to T cell epitopes in IA2 and GAD65, bind strongly to HLA-DRB1*04 molecules that confer susceptibility to type 1 diabetes and are also T cell epitopes in humans at risk for type 1 diabetes.
20082482 HLA-DRB1*04 and DQB1*03 alleles, but not HLA-B8-DRB1*03, may predispose to autoimmune gastritis.
20082482 Observational study of gene-disease association. (HuGE Navigator)
20075704 Observational study of gene-disease association. (HuGE Navigator)
20073992 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20073143 In the current study the genotypes most associated with type 1 diabetes mellitus were HLA-DQA1*03/-, -DQA1 *03/05, -DQB1*02/*0302,and -DRB1*0401/*0402.
20073143 Observational study of gene-disease association. (HuGE Navigator)
20070603 Observational study of gene-disease association. (HuGE Navigator)
20062572 Observational study of gene-disease association. (HuGE Navigator)
20054547 Encounter of variant allogeneic FVIII presented on a suitable MHC background could be a risk factor for inhibitor formation.
20054547 Observational study of gene-disease association. (HuGE Navigator)
20051322 The study reports a comparison of HLA-DRB1 and -DQB1 frequencies in a group of 45 Brazilian acute leukemia patients and 100 Brazilian healthy controls.
20051322 Observational study of gene-disease association. (HuGE Navigator)
20038641 Peptides derived from influenza hemagglutinin by cycle mutation interact cooperatively with an HLA-DR1 molecule lacking the conserved hydrogen bond formed by histidine-beta81, so that intrinsic peptide release is an unfolding event.
20031464 Observational study of gene-disease association. (HuGE Navigator)
20030936 Antigen frequencies and allele frequencies of HLA-DRB1*15 in childhood patients with ALL were higher than in controls.
20030936 Observational study of gene-disease association. (HuGE Navigator)
20028711 HLA-DRB1 alleles influence susceptibility to anti-aquaporin 4 antibody positive multiple sclerosis in Japanese patients.
20028711 Observational study of gene-disease association. (HuGE Navigator)
20018961 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
20018638 Month of birth, HLA-DRB1 genotype, and risk of multiple sclerosis are associated. The interaction of a seasonal risk factor with loci at or near HLA-DRB1 during gestation or shortly after birth is implicated.
20018638 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20017299 DRB1 * 1454 and DRB1 * 1405 were the most common alleles of HLA-DRB1 in Chinese Han populations.
20017299 Observational study of genotype prevalence. (HuGE Navigator)
20012522 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
20008659 Carriership of HLA-DRB1*1501 was associated with the extent of focal abnormalities in the spinal cord in multiple sclerosis.
20006387 This study indicated that in this multiple sclerosis population allelic heterogeneity at the HLA-DRB1 locus may have modifying effects on disease severity as well as susceptibility.
20006387 Observational study of gene-disease association. (HuGE Navigator)
20003377 Observational study of gene-disease association. (HuGE Navigator)
20003324 HLA-DRB1 alleles are associated with leprosy susceptibility in a Chinese population
20003324 Observational study of gene-disease association. (HuGE Navigator)
20003137 Observational study of genotype prevalence. (HuGE Navigator)
20003135 Observational study of genotype prevalence. (HuGE Navigator)
20002609 Observational study of gene-disease association. (HuGE Navigator)
19995849 These findings indicate that epistatic interactions at the HLA-DRB1 locus have significant modifying effects on age at onset of multiple sclerosis
19995849 Observational study of gene-disease association. (HuGE Navigator)
19995845 Observational study of gene-disease association. (HuGE Navigator)
19965521 Both the DPB1*0501 allele and the DRB1*1602- DPB1*0501 haplotype are strong predisposing factors for conventional multiple sclerosis in Southern Han Chinese.
19965521 Observational study of gene-disease association. (HuGE Navigator)
19956635 Uncategorized study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19956544 Haplotypes, constructed for four single nucleotide polymorphisms in the VDR gene, were studied for their interaction with HLA-DRB1 alleles in 233 Type 1 diabetes patients and 191 healthy controls from North India.[HLA DRB1 0301]
19956544 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19949652 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19937591 Observational study of gene-disease association. (HuGE Navigator)
19931565 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19927159 Observational study of gene-disease association. (HuGE Navigator)
19925877 Observational study of gene-disease association. (HuGE Navigator)
19924143 Observational study of gene-disease association. (HuGE Navigator)
19922436 Observational study of gene-disease association. (HuGE Navigator)
19920092 Observational study of gene-disease association. (HuGE Navigator)
19908388 Identified a set of amino acid variations, particularly pockets of the peptide binding site, that account for the juvenile idiopathic arthritis risk attributable to HLA DRB1.
19906105 Observational study of gene-disease association. (HuGE Navigator)
19898480 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19896562 HLA-DRB1*1501 and HLA-DRB1*1503 alleles are risk factors for multiple sclerosis in Colombia
19896562 Meta-analysis of gene-disease association. (HuGE Navigator)
19896518 Observational study of gene-disease association. (HuGE Navigator)
19895570 Observational study of genotype prevalence. (HuGE Navigator)
19894308 The biological properties of the MS-associated genes support the notion that autoimmune inflammatory processes play an important role in MS
19894308 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19890026 Observational study of gene-disease association. (HuGE Navigator)
19886988 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19884273 Observational study of gene-disease association. (HuGE Navigator)
19884265 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
19879913 We conclude that HLA-DRB1*01 and -B*27 alleles and low plasma IgG1 levels may be significant risk factors for recurrent lymphocytic meningitis .
19879913 Observational study of gene-disease association. (HuGE Navigator)
19879597 Our study is the first to show that HLA-DRB1 allele interactions and dose-effects influence the frequency of oligoclonal bands in multiple sclerosis
19879597 Observational study of gene-disease association. (HuGE Navigator)
19879194 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19874322 Observational study of gene-disease association. (HuGE Navigator)
19865102 Observational study of gene-disease association. (HuGE Navigator)
19865101 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
19861144 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19860744 Observational study of gene-disease association. (HuGE Navigator)
19860590 association of DRB1*15 allele with aplastic anemia in Pakistani patients
19860590 Observational study of gene-disease association. (HuGE Navigator)
19858318 Observational study of gene-disease association. (HuGE Navigator)
19854714 Observational study of gene-disease association. (HuGE Navigator)
19851445 Observational study of gene-disease association. (HuGE Navigator)
19847191 HLA DRB1*1454 but not HLA DRB1*1401 is linked to pemphigus vulgaris in white Europeans
19845915 Observational study of genotype prevalence. (HuGE Navigator)
19837788 Observational study of gene-disease association and genetic testing. (HuGE Navigator)
19834793 Observational study of gene-disease association. (HuGE Navigator)
19833889 Observational study of gene-disease association. (HuGE Navigator)
19822091 Molecular study of receptor for advanced glycation endproduct gene promoter and identification of specific HLA haplotypes possibly involved in chronic fatigue syndrome.
19822091 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19820376 Observational study of gene-disease association. (HuGE Navigator)
19820007 Observational study of gene-disease association. (HuGE Navigator)
19819281 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19817985 Observational study of gene-disease association. (HuGE Navigator)
19812988 Observational study of gene-disease association. (HuGE Navigator)
19811438 primary biliary cirrhosis patients had a higher gene frequency of HLA-DR4 and DR1 compared to healthy controls and patients with overlap syndromes
19811438 Observational study of gene-disease association. (HuGE Navigator)
19811437 Increased significance frequency of DRB1*1503 allele was found among Chagas cardiomyopathy patients suggesting that this antigen might be related with the genetic susceptibility to cardiac damage in these patients (
19811437 Observational study of gene-disease association. (HuGE Navigator)
19811436 The association of TNF-alpha; -308*A with polyglandular autoimmunity might be directly or indirectly due to the association with HLA-DRB1*03.
19811436 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19770068 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
19769302 Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of West Siberia
19761839 Observational study of gene-disease association. (HuGE Navigator)
19758311 The identification of HLA-DRB1*0337, using sequence-based typing (SBT) method, in a Taiwanese bone marrow, is reported.
19758204 Data show that an age at CFS onset (ACFSO) during the third decade of life was associated with the serotonin receptor AA genotype and the HLA-DRB1*03 allele.
19758202 Data show that HLA-DRB1*03 is a susceptibility allele in Portuguese SLE patients, while HLA-DRB1*09 and DRB1*13 alleles may be protective alleles, not only for the disease, but for the development of nephritis.
19758199 Data show a distinct genetic risk of developing PBC in the Italian population, with no interaction between the HLA and TNF alleles.
19758199 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19758198 Studies revealed that HLA-DRB1*1501 association was with CDLE and SLE, and association between HLA-Cw6 and CDLE was first reported in a Japanese population.
19758197 Results confirmed that the HLA-DRB1 and HLA-DQB1 profile of PAPS and SAPS is different.
19756183 This finding suggests that HLA-DRB1 *0405 allele might play a role in the pathogenesis of Vogt-Koyanagi-Harada disease.
19756183 Observational study of gene-disease association. (HuGE Navigator)
19744147 Thirty-six novel HLA alleles: 7 HLA-A, 11 HLA-B, 15 HLA-C and 3 HLA-DRB1.
19741715 Observational study of gene-disease association. (HuGE Navigator)
19741008 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19740903 Hormone replacement therapy may reduce the risk of rheumatoid arthritis due to HLA-DRB1 *01 and/or *04 alleles by protecting against the production of anti-CCP antibodies.
19740903 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19738989 The presence of high anti-Cyclic Citrullinated peptide antibody titers was associated with more active, aggressive and erosive disease as determined by SDAI and Larsen scores.
19738989 Observational study of gene-disease association. (HuGE Navigator)
19733917 Antibodies against Epstein-Barr virus protein EBNA-1 (amino acid 385-420) in HLA DRB1*1501 positive individuals are associated with a 24-fold risk increase for multiple sclerosis.
19728932 Observational study of gene-disease association. (HuGE Navigator)
19722042 Observational study of gene-disease association. (HuGE Navigator)
19720533 The findings of this study indicated that interactions between the HLA-DRB1*03 allele and other alleles at the DRB1 locus can influence disease susceptibility and the clinical phenotype in sIBM.
19720533 Observational study of gene-disease association. (HuGE Navigator)
19718441 Observational study of gene-disease association. (HuGE Navigator)
19714585 PTPN22 appears to be associated with anticitrulline autoimmunity, and HLA-DRB1 is independently associated with rheumatoid factor. Specific gene-environment combinations are associated with an increased risk of developing rheumatoid arthritis.
19714482 Observational study of gene-disease association. (HuGE Navigator)
19703245 Observational study of gene-disease association. (HuGE Navigator)
19703234 Observational study of genotype prevalence. (HuGE Navigator)
19702653 Observational study of gene-disease association. (HuGE Navigator)
19700393 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19698125 Observational study of gene-disease association. (HuGE Navigator)
19692729 Observational study of gene-disease association. (HuGE Navigator)
19690132 Observational study of gene-disease association. (HuGE Navigator)
19683555 Observational study of gene-disease association. (HuGE Navigator)
19674023 This study suggests that HLA-DRB1 alleles were associated with the clinical course of disease and steroid dependence in UC patients.
19674023 Observational study of gene-disease association. (HuGE Navigator)
19674013 Observational study of gene-disease association. (HuGE Navigator)
19668019 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19664674 Observational study of genotype prevalence. (HuGE Navigator)
19663932 Observational study of gene-disease association. (HuGE Navigator)
19659809 Observational study of gene-disease association. (HuGE Navigator)
19655145 Observational study of gene-disease association. (HuGE Navigator)
19654877 Observational study of gene-disease association. (HuGE Navigator)
19654554 Observational study of gene-disease association. (HuGE Navigator)
19654407 Observational study of gene-disease association. (HuGE Navigator)
19654074 HLA-DRB1*1501 allele is a genetic marker for susceptibility to anti-glomerular basement membrane (GBM) disease in Chinese.
19654074 Observational study of gene-disease association. (HuGE Navigator)
19653987 Observational study of gene-disease association. (HuGE Navigator)
19648278 Investigation of HLA-DRB1*0901 binding motif demonstrates a clear interaction between T- cell peptide epitope-binding pockets 6 and 9.
19648126 Observational study of gene-disease association. (HuGE Navigator)
19630074 Carriage of the ligand of inhibitory KIR3DL1 receptor HLA-Bw4 is found to protect against mltiple sclerosis in an HLA-DRB1 independent manner.
19630074 Observational study of gene-disease association. (HuGE Navigator)
19629136 Parent-of-origin of HLA-DRB1*1501 is associated with the age of onset of multiple sclerosis.
19629136 Observational study of gene-disease association. (HuGE Navigator)
19625333 The probability of carrying a neutral genotype was 1.76-fold higher in the younger than in the older cohort (P = 0.02) and 3.67-fold higher in men (P = 0.005)
19625333 Observational study of gene-disease association. (HuGE Navigator)
19624613 An HLA-DR11/DQ3 haplotype with a DRB1*0301 sequence motif in the third hypervariable region of the HLA-DR beta-1 chain is associated with the European Caucasian family
19620308 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
19616314 Observational study of gene-disease association. (HuGE Navigator)
19597844 Response of HLA-DRB1 genotypes with various antibody responses to hepatitis B vaccine in adolescents and young adults.
19597844 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19597292 Observational study of gene-disease association. (HuGE Navigator)
19596691 Observational study of gene-disease association. (HuGE Navigator)
19593744 The presence of the HLA-DR15 allele is indicative of a genetic susceptibility to myelodysplastic syndrome. HLA-DR15 showed less association with disease progression and greater association with bone marrow failure.
19593744 Observational study of gene-disease association. (HuGE Navigator)
19592628 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19589487 Observational study of gene-disease association. (HuGE Navigator)
19587357 Meta-analysis of gene-disease association. (HuGE Navigator)
19585495 HLA-DRB1 polymorphisms are associated with cervical cancer.
19585166 Observational study of gene-disease association. (HuGE Navigator)
19571811 Observational study and genome-wide association study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19565552 Observational study of gene-disease association. (HuGE Navigator)
19553558 Observational study of gene-disease association. (HuGE Navigator)
19544559 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19543371 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19539218 Observational study of gene-disease association. (HuGE Navigator)
19523767 Observational study of gene-disease association. (HuGE Navigator)
19516267 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19502265 Results suggest that in Taiwanese people, DRB1*0301 and DRB1*1501 alleles are significant risk factors for systemic lupus erythematosus, while the DRB1*1202 allele is protective for lupus nephritis.
19502265 Observational study of gene-disease association. (HuGE Navigator)
19500315 Observational study of gene-disease association. (HuGE Navigator)
19495996 Observational study of gene-disease association. (HuGE Navigator)
19493426 Meta-analysis of gene-disease association. (HuGE Navigator)
19493234 Observational study of gene-disease association. (HuGE Navigator)
19493233 Observational study of genotype prevalence. (HuGE Navigator)
19490212 Observational study of gene-disease association. (HuGE Navigator)
19490211 Observational study of genotype prevalence. (HuGE Navigator)
19487887 This study showed that significant expression of HLA-DRB1 genotypes in patients with human high-grade gliomas in Sicily.
19487887 Observational study of gene-disease association. (HuGE Navigator)
19487610 Observational study of gene-disease association. (HuGE Navigator)
19486004 Observational study of gene-disease association. (HuGE Navigator)
19482867 Observational study of gene-disease association. (HuGE Navigator)
19482865 high incidence of brainstem and cerebellar involvement might be explained by the greater severity of muleiple sclerosis and the high frequency (60%) of carriage of DRB1*04, DRB1*07, and/or DRB1*13 alleles
19482865 Observational study of gene-disease association. (HuGE Navigator)
19481774 Observational study of gene-disease association. (HuGE Navigator)
19480851 Observational study of genotype prevalence. (HuGE Navigator)
19479873 There is a statistically significant interaction between distinct DRB1 shared epitope alleles and smoking in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis.
19479873 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19479859 Observational study of gene-disease association. (HuGE Navigator)
19474744 This study found a high frequency of DQ2 haplotype in celiac disease and identified new protective alleles DRB1*13, DQA1*0102 and DQB1*06, however, HLA polymorphism seems to have no evident impact on clinical outcome of celiac disease.
19474744 Observational study of gene-disease association. (HuGE Navigator)
19473559 Observational study of gene-disease association. (HuGE Navigator)
19473214 There is a significantly higher occurrence of HLA-DRB1*09 and HLA-B*46-DRB1*09 in patients with haemorrhagic fever with renal syndrome (HFRS) compared to the control group
19473214 Observational study of gene-disease association. (HuGE Navigator)
19449444 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
19445991 Data show that HLA-DRB1*1202, the predominant allele in the Vietnamese population showed the strongest association with SARS in a dominant model.
19439981 The HLA DRB1*1501-DQB1*0602-DPB1*0501 haplotype may be a genetic marker for the development of toluene diisocyanate-induced asthma in Koreans.
19433080 significant association of rs3135388 A allele carriership with MS in patients from Serbia
19433080 Observational study of gene-disease association. (HuGE Navigator)
19429597 Observational study of gene-disease association. (HuGE Navigator)
19421224 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19416238 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19411392 Observational study of gene-disease association. (HuGE Navigator)
19411391 Observational study of gene-disease association. (HuGE Navigator)
19409091 Observational study of gene-disease association. (HuGE Navigator)
19407364 Observational study of gene-disease association. (HuGE Navigator)
19405864 Observational study of gene-disease association. (HuGE Navigator)
19404393 Japanese CNS hypersomnias (essential hypersomnia: EHS) other than narcolepsy with cataplexy was significantly associated with SNP rs5770917 (located between CPT1B and CHKB) and HLA-DRB1*1501-DQB1*0602 haplotype
19404393 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19401421 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19392836 HLA-B40-DRB1*1501 and HLA-B40-DRB1*04 haplotypes may be associated with susceptibility to HIV infection and to pulmonary tuberculosis in HIV patients.
19392836 Observational study of gene-disease association. (HuGE Navigator)
19392788 these data provide further evidence of heterogeneity at the DRB1 locus and confirm the importance of HLA variants in the phenotypic expression of Multiple Sclerosis.
19392788 Observational study of gene-disease association. (HuGE Navigator)
19390203 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19387463 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19382531 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19382529 both Lofgren's and chronic sarcoidosis subjects expressed HLA-DR allele combinations capable of M. tuberculosis and M. avium epitope recognition at higher affinity than tuberculosis affected subjects
19380721 Two Canadian cohorts (n = 830 and n = 438 trios) genotyped for HLA-DRB1, HLA-DQA1 and HLA-DQB1 alleles were tested for association with multiple sclerosis using transmission disequilibrium test.
19380721 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19374512 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19364514 Observational study of genotype prevalence. (HuGE Navigator)
19364369 The present Argentinian human leukocyte antigen class II population study is in accordance with other Caucasian multiple sclerosis surveys which have found that HLA-DRB1*15 allele is strongly associated with multiple sclerosis disease.
19364369 Observational study of gene-disease association. (HuGE Navigator)
19350523 Observational study of genotype prevalence. (HuGE Navigator)
19349081 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19348686 Observational study of genotype prevalence. (HuGE Navigator)
19337647 Observational study of gene-disease association. (HuGE Navigator)
19333951 genetic predisposition plays an important role in the pathogenesis of anti-citrullinated protein antibody-negative rheumatoid arthritis
19333951 Observational study of gene-disease association. (HuGE Navigator)
19333936 the DRB1*13 allele plays a dual role in the development of rheumatoic arthritis, by protecting against anti-citrullinated protein antibody(ACPA)-positive but, in combination with DRB1*03, increasing the risk of ACPA-negative
19333936 Observational study of gene-disease association. (HuGE Navigator)
19333928 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19332633 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19332095 Observational study of gene-disease association. (HuGE Navigator)
19327846 Both carriage of HLA-DRB1*15 and the presence of OCB hastened attainment of EDSS 6.0. in multiple sclerosis.
19327239 an increased frequency of Cardiovacular events ocurred in rheumatoid arthritis patients with HLA-DRB1*0404 allele and homozygosity for nitric oxide synthase 3 (NOS3)-786 TT genotype or for the presence of long NOS2A (nitric oxide synthase A) alleles
19327239 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19299434 The frequencies of HLA-DQA1, DQB1, and HLA-DRB1 DR2 alleles in the neuromyelitis optica group were intermediate between the healthy control group and the multiple sclerosis group
19299434 Observational study of gene-disease association. (HuGE Navigator)
19295542 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19290000 Observational study of gene-disease association. (HuGE Navigator)
19287509 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
19286445 Observational study of genotype prevalence. (HuGE Navigator)
19272325 Results demonstrated that HLA DR-DQ polymorphisms are involved in genetic susceptibility to cervical cancer or HPV infection in a northern Indian population.
19272325 Observational study of gene-disease association. (HuGE Navigator)
19262578 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19254257 Observational study of gene-disease association. (HuGE Navigator)
19254255 Observational study of gene-disease association. (HuGE Navigator)
19254248 Observational study of gene-disease association. (HuGE Navigator)
19251712 Observational study of gene-disease association. (HuGE Navigator)
19248090 Observational study of gene-disease association. (HuGE Navigator)
19247821 Observational study and clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19246116 Observational study of gene-disease association. (HuGE Navigator)
19243543 HLA-DRB1*0901 is significantly more prevalent in the anti-"Mi(a)" patients group than in the control group.
19243543 Observational study of gene-disease association. (HuGE Navigator)
19235869 HLA-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus
19235869 Observational study of gene-disease association. (HuGE Navigator)
19235017 Observational study of gene-disease association. (HuGE Navigator)
19233472 Observational study of gene-disease association. (HuGE Navigator)
19232439 The peptides were modelled into the binding groove of HLA-DRB1*0101 using different amino acid substitution tools.
19230187 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19227412 Observational study of gene-disease association. (HuGE Navigator)
19223392 Observational study of gene-disease association. (HuGE Navigator)
19221531 Observational study of gene-disease association. (HuGE Navigator)
19219503 Observational study of gene-disease association. (HuGE Navigator)
19214504 Observational study of gene-disease association. (HuGE Navigator)
19210888 certain HLA-DRB1 alleles reported previously as susceptibility factors are strongly associated with juvenile idiopathic arthritis in a Hungarian population
19210888 Observational study of gene-disease association. (HuGE Navigator)
19210322 Observational study of gene-disease association. (HuGE Navigator)
19208355 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19204171 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19204159 Subjects with DRB1*15 alleles were twice as likely to have typical MS rather than opticospinal MS.
19204159 Observational study of gene-disease association. (HuGE Navigator)
19201236 Observational study of gene-disease association. (HuGE Navigator)
19200828 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19199259 Observational study of gene-disease association. (HuGE Navigator)
19199253 The PADI4 SNPs and haplotypes are associated with RA susceptibility in Chinese. HLA-DRB1 shared epitope is also an important risky factor for RA.
19199253 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19197344 Sequence analysis localised a single MHC vitamin D response element (VDRE) to the promoter region of HLA-DRB1
19196481 Observational study of gene-disease association. (HuGE Navigator)
19193207 empirical evidence based on sequence information suggests that multiple sclerosis susceptibility arises primarily from amino acid 13
19193207 Observational study of gene-disease association. (HuGE Navigator)
19188433 Observational study of gene-disease association. (HuGE Navigator)
19180512 Observational study of gene-disease association. (HuGE Navigator)
19167759 Observational study of gene-disease association. (HuGE Navigator)
19165231 Observational study of gene-disease association. (HuGE Navigator)
19159415 Observational study of gene-disease association. (HuGE Navigator)
19156166 Observational study of gene-disease association. (HuGE Navigator)
19155468 HLA-DRB1*1501 (DR2b) transgene is a permissive allele for prostate specific antigen, whereas histocompatibility class II allele I-A(b) cannot accommodate a strong CD4 T cell response to PSA.
19154326 Case Report: HLA-DQ alpha heterodimers and HLA-DR alleles in tubulointerstitial nephritis and uveitis syndrome.
19153174 DRB1*15 and infectious mononucleosis may act in synergy causing multiple sclerosis
19151010 gene-environment interactions in rheumatoid arthritis (RA) in a cohort of Caucasian US women demonstrates a significant additive and multiplicative interaction between the strongest genetic risk factor for RA, the HLA-SE, and heavy cigarette smoking
19151010 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19144284 Observational study of gene-disease association. (HuGE Navigator)
19143821 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19143818 Observational study of gene-disease association. (HuGE Navigator)
19143814 Observational study of gene-disease association. (HuGE Navigator)
19143813 Observational study of gene-disease association. (HuGE Navigator)
19143812 Observational study of gene-disease association. (HuGE Navigator)
19143811 Observational study of gene-disease association. (HuGE Navigator)
19143810 Observational study of gene-disease association. (HuGE Navigator)
19140832 HLA allele and haplotype frequencies in addition to phylogenetic tree and principal component analyses based on the four-digit sequence-level allele frequencies for HLA-A, HLA-B, and HLA-DRB1 showed that Western Javanese was closest to Southeast Asians.
19140832 Observational study of genotype prevalence. (HuGE Navigator)
19140826 Observational study of gene-disease association. (HuGE Navigator)
19127112 Observational study of genotype prevalence. (HuGE Navigator)
19124916 Observational study of gene-disease association. (HuGE Navigator)
19120278 Observational study of gene-disease association. (HuGE Navigator)
19120272 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19117726 the effect of HLA-DRB1 shared epitope and anti-CCP seropositivity on erosive rheumatoid arthritis
19117726 Observational study of gene-disease association. (HuGE Navigator)
19117368 microchimerism can contribute to the risk of an autoimmune disease by providing HLA susceptibility alleles
19116923 results confirm the polygenic contribution of the major histocompatibility to rheumatoid arthritis and implicate 2 additional non-DRB1 susceptibility loci.
19116923 Observational study of gene-disease association. (HuGE Navigator)
19116921 HLA-DPB1 is an independent risk locus for antibody to citrullinated protein-positive rheumatoid arthritis
19104471 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19098025 HLA-DRB1*15 is the main risk allele for multiple sclerosis.
19098025 Observational study of gene-disease association. (HuGE Navigator)
19096254 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19070257 HLA-DR alleles associated with susceptibility to tuberculosis may be endowed with a reduced capability to bind at high affinity T-cell epitopes and select them for antigen presentation.
19058789 Observational study of gene-disease association. (HuGE Navigator)
19055605 Observational study of gene-disease association. (HuGE Navigator)
19052351 Observational study of gene-disease association. (HuGE Navigator)
19052350 Observational study of gene-disease association. (HuGE Navigator)
19047245 Observational study of gene-disease association. (HuGE Navigator)
19046304 This study could imply the possible role of HLA-DRB1*07 in the incidence of aplastic anaemia. Moreover, the frequency of DRB1*04, DRB1*03 and DRB1*15 alleles showed intermediate correlation with Fanconi's anaemia.
19046304 Observational study of gene-disease association. (HuGE Navigator)
19046302 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19046300 Observational study of gene-disease association. (HuGE Navigator)
19041429 Meta-analysis of gene-disease association. (HuGE Navigator)
19032829 The majority of anti-GPI(glucose6phosphate isomerase) Ab-positive Rheumatoid arthritis (RA) patients constitute a subset of HLA-DRB1* Shared epitope-associated, anti-cyclic citrullinated peptide antibod7- positive RA patients.
19032829 Observational study of gene-disease association. (HuGE Navigator)
19031816 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19030725 Observational study of gene-disease association. (HuGE Navigator)
19024262 Observational study of genotype prevalence. (HuGE Navigator)
19023492 Observational study of gene-disease association. (HuGE Navigator)
19022862 findings suggest that DRB1*1501 increases disease severity in MS by facilitating the development of more T2-foci, thereby increasing the potential for irreversible axonal compromise and subsequent neuronal degeneration.
19022862 Observational study of gene-disease association. (HuGE Navigator)
19005023 Observational study of gene-disease association. (HuGE Navigator)
19003916 Associated DRB1 alleles were found only in a minority of primary biliary cirrhosis patients, whereas an additive genetic model is supported by the gene dosage effect for DRB1*11 allele and the interaction of DRB1*11,*13, and *08.
19003916 Observational study of gene-disease association. (HuGE Navigator)
19002558 The combination of the polymorphism of the tumor necrosis factor alpha upstream promoter region and HLA-DRB1 allele was associated with radiological progression in the early stage of rheumatoid arthritis.
19002558 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19000143 Observational study of gene-disease association. (HuGE Navigator)
19000142 Observational study of genetic testing. (HuGE Navigator)
19000140 Observational study of genotype prevalence. (HuGE Navigator)
19000139 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18998014 Observational study of gene-disease association. (HuGE Navigator)
18996998 There is a known association between HLA-DRB1*03 and Lofgren's syndrome.
18987644 Observational study of gene-disease association. (HuGE Navigator)
18976440 Observational study of gene-disease association. (HuGE Navigator)
18976433 in Caucasians of Northern European origin, HLA-DRB1*15 is associated with risk of developing KD following injury
18976433 Observational study of gene-disease association. (HuGE Navigator)
18976432 Observational study of genotype prevalence. (HuGE Navigator)
18958335 Observational study of gene-disease association. (HuGE Navigator)
18955792 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18955791 Observational study of gene-disease association. (HuGE Navigator)
18952831 The characteristic MRI features of multiple sclerosis in Asians are partly related to distinct HLA-DRB1 gene alleles and an absence of oligoclonal bands
18952831 Observational study of gene-disease association. (HuGE Navigator)
18945465 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
18945361 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18939942 Observational study of gene-disease association. (HuGE Navigator)
18932050 Observational study of gene-disease association. (HuGE Navigator)
18930994 Observational study of gene-disease association. (HuGE Navigator)
18922348 Present results suggest that there is a significant relationship between nasal polyposis and HLA-DRB1 allele frequency among the Turkish population.
18922348 Observational study of gene-disease association. (HuGE Navigator)
18854880 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18846964 Observational study of gene-disease association. (HuGE Navigator)
18838388 Observational study and meta-analysis of gene-disease association and gene-gene interaction. (HuGE Navigator)
18835879 Observational study of gene-disease association. (HuGE Navigator)
18832704 roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis
18832704 Observational study of gene-disease association. (HuGE Navigator)
18827882 The HLA-DRB1*0901 frequency was significantly decreased in secondary infection of dengue shock syndrome.
18824733 Observational study of gene-disease association. (HuGE Navigator)
18822201 The distribution of mononucleotide polymorphism of five regulation regions of alpha-IFN among HLA-DRB1*11 gene episodes affects the IFN anti-virus treatment.
18822201 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18821214 DRB1*04 and DQB1*02 alleles might be risk factors for the occurrence of hepatocellular carcinoma (OR = 4.373 and 3.807, respectively), and DQB1*06 may be a protective allele (OR = 0.259).
18821214 Observational study of gene-disease association. (HuGE Navigator)
18820539 Data supports the hypothesis that HLA-DRB1*04 may be considered a risk factor, and HLA-DRB1*13 a protective factor, for malignant progression of cervical intraepithelial neoplasia in Argentine women
18820539 Observational study of gene-disease association. (HuGE Navigator)
18812394 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18801688 DRB1*04 predisposes to rheumatoid arthritis while DRB1*07 seems protective for the Moroccan patients population.
18801688 Observational study of gene-disease association. (HuGE Navigator)
18799094 HLA-DRB1*0404 allele was the most strongly associated with the presence of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis sera; HLA-DRB1*0404 patients had higher titers
18799094 Observational study of gene-disease association. (HuGE Navigator)
18797890 Observational study of gene-disease association. (HuGE Navigator)
18794605 Observational study of gene-disease association. (HuGE Navigator)
18791284 results revealed DRB1*0101 & DRB1*0301 alleles were more frequent in Papillon-Lefevre syndrome (PLS) patients than normal controls, but there was no significant difference; results showed no strong association between HLA class II alleles & PLS
18789688 Data show that no significant differences are detected between HLA-DRB1*15 polymorphism and chronic dysimmune polyneuropathy.
18789688 Observational study of gene-disease association. (HuGE Navigator)
18780165 Observational study of gene-disease association. (HuGE Navigator)
18779568 Observational study of gene-disease association. (HuGE Navigator)
18778327 The comparison of HLA class II allele frequencies of Bais with those of other Chinese populations suggested that the Bai ethnic group belonged to the southern group of Chinese.
18778327 Observational study of genotype prevalence. (HuGE Navigator)
18768435 Observational study of gene-disease association. (HuGE Navigator)
18765817 These findings strongly imply that differences among HLA-DRB1*15 haplotypes will furnish the basis for Major Histocompatibility Complex-associated susceptibility in multiple sclerosis.
18765817 Observational study of gene-disease association. (HuGE Navigator)
18764812 Observational study of gene-disease association. (HuGE Navigator)
18761557 HLA-DRB1*13 was closely related with protection against persisting hepatitis B in an Iranian population.
18761557 Observational study of gene-disease association. (HuGE Navigator)
18726686 Observational study of gene-disease association. (HuGE Navigator)
18722491 Observational study of gene-disease association. (HuGE Navigator)
18721466 Observational study of gene-disease association. (HuGE Navigator)
18721277 In Caucasoids of European origin, HLA-DRB1*15 is associated with risk of developing Dupuytren's disease.
18721271 HLA-A, -B and -DRB1 allele frequencies in the Bangladeshi population.
18721271 Observational study of genotype prevalence. (HuGE Navigator)
18718089 The gene frequency of HLA-A*24, HLA- DRB1*14 in CML patients is significantly lower than normal people in Guangdong.
18718089 Observational study of gene-disease association. (HuGE Navigator)
18716994 Observational study of genotype prevalence. (HuGE Navigator)
18713991 profound T cell tolerance to the high-affinity MHC-binding hMBP82-100 epitope was observed in HLA-DRB1*1501, HLA-DRB5*0101, and HLA-DRB1*0401 Tg mouse lines
18706091 Observational study of gene-disease association. (HuGE Navigator)
18694972 Observational study of genetic testing. (HuGE Navigator)
18689790 There is an association of HLA-DRB1*09-DQB1*0309 and anti-r-HuEpo associated pure red cell aplasia cases. This association may be used in identifying the risk of the patients.
18689790 Observational study of gene-disease association. (HuGE Navigator)
18684978 DRB1 shared epitope predisposes transgenic mice to develop arthritis by activation of the autoreactive T cells and protects from arthritis by deletion of autoreactive T cells and generation of regulatory T cells.
18684745 Observational study of gene-disease association. (HuGE Navigator)
18683155 Observational study of genotype prevalence. (HuGE Navigator)
18672082 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
18656179 HLA-DRB1*0401 and HLA-DRB1*0408 have a role in the development of antibodies against interferon-beta therapy in multiple sclerosis
18635594 Observational study of gene-disease association. (HuGE Navigator)
18623133 It is possible that HLA-DRB1(*)01 and DRB1(*)04 alleles could be associated with the delta 32-bp deletion of CCR5.
18623133 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18615093 Study shows that HLA-DRB1*15 allele modulates the course of multiple sclerosis for relapsing-remitting (RR) onset patients likely by precipitating the secondary progressive (SP) phase.
18615093 Observational study of gene-disease association. (HuGE Navigator)
18613417 Observational study of gene-disease association. (HuGE Navigator)
18599937 Observational study of gene-disease association. (HuGE Navigator)
18593440 Observational study of gene-disease association. (HuGE Navigator)
18589099 Observational study of gene-disease association. (HuGE Navigator)
18588574 Observational study of gene-disease association. (HuGE Navigator)
18583252 Observational study of gene-disease association. (HuGE Navigator)
18582515 Observational study of gene-disease association. (HuGE Navigator)
18580885 Observational study of gene-disease association. (HuGE Navigator)
18571007 In Koreans, DRB1*1501 was associated with disease susceptibility to aplastic anemia and DRB1*1302 with protection against the severe form of the disease
18571007 Observational study of gene-disease association. (HuGE Navigator)
18569076 Observational study of gene-disease association. (HuGE Navigator)
18565729 Observational study of gene-disease association. (HuGE Navigator)
18565258 Observational study of gene-disease association. (HuGE Navigator)
18565246 Observational study of gene-disease association. (HuGE Navigator)
18561316 in ovarian carcinoma, a semiquantitative analysis was performed for HLA-class II loci DRB1 and DQB1 in malignant and normal ovarian tissue
18554163 investigation of the association of polymorphisms of HLA class II DRB1 & DQB1 alleles & risk for intrahepatic cholestasis of pregnancy (ICP); results indicate that HLA-DR11 allele is associated with the susceptibility of ICP in the Chinese Changsha area
18554163 Observational study of gene-disease association. (HuGE Navigator)
18544086 Observational study of gene-disease association. (HuGE Navigator)
18537178 Observational study of gene-disease association. (HuGE Navigator)
18535809 Observational study of gene-disease association. (HuGE Navigator)
18523354 Comparison between responders and non-responders revealed only a significant difference for DQB10201 allele
18523354 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18521924 Observational study of gene-disease association. (HuGE Navigator)
18520346 Observational study of gene-disease association. (HuGE Navigator)
18520158 The association of HLA-DRB1*01 and HLA-DRB*15 alleles with idiopathic chronic urticaria (CU) suggests that there is a genetic component in the pathogenesis of CU.
18520158 Observational study of gene-disease association. (HuGE Navigator)
18513341 CCR2 haplotype 2 and HLA-DRB1*0301 are independent genetic risk factors for Lofgren's syndrome.
18513341 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18504544 High IA-2A prevalence in patients carrying DRB1*04, DRB1*07 and DRB1*09 alleles in type 1 diabetes.
18504544 Observational study of gene-disease association. (HuGE Navigator)
18501999 Observational study of gene-disease association. (HuGE Navigator)
18489735 identified sequence features could putatively act in recombination allowing either less (CpG dinucleotides) or more specific DNA cleavage (complex sequences) or homologous recombination (complex sequences)
18487476 Diagnosis of type 1 diabetes associated with unchanged incidence of DRB1 genotype frequency.
18487476 Observational study of gene-disease association. (HuGE Navigator)
18482373 Observational study of gene-disease association. (HuGE Navigator)
18481581 Observational study of gene-disease association. (HuGE Navigator)
18466541 Observational study of gene-disease association. (HuGE Navigator)
18466515 Genome-wide association study of gene-disease association. (HuGE Navigator)
18466483 Observational study of gene-disease association. (HuGE Navigator)
18466466 Observational study of gene-disease association. (HuGE Navigator)
18465452 prevalence of the shared epitope is significantly lower in Chinese rheumatoid arthritis patients,as compared with previous reports of a study using a Caucasian cohort.
18465452 Observational study of gene-disease association. (HuGE Navigator)
18463715 Observational study of gene-disease association. (HuGE Navigator)
18451182 Co-occurring HLA alleles across loci seem to be more important than individual allelesin squamous cell cervical cancer risk.
18451182 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18450852 Observational study of gene-disease association. (HuGE Navigator)
18449568 HLA-DRB1*13 could be a risk factor for developing nephrotic-range proteinuria in Henoch Schonlein purpura patients
18449568 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18449200 Analysis of HLA-DRB1 antigen and HLA-DQ antigens in Hashimoto thyroiditis and Graves disease reveals differences between the two.
18449200 Observational study of gene-disease association. (HuGE Navigator)
18438843 Observational study of gene-disease association. (HuGE Navigator)
18433881 Observational study of gene-disease association. (HuGE Navigator)
18416774 HLA-DRB1*09 is associated with the age at diagnosis and HLA-DRB1*08 is associated with the disease extent of ulcerative colitis in Japanese
18416774 Observational study of gene-disease association. (HuGE Navigator)
18413431 Japanese patients with anti-GBM antibody-mediated disease are very likely to carry the HLA-DRB1(*)1501 but not the HLA-DRB1(*)1502 allele.
18413431 Observational study of gene-disease association. (HuGE Navigator)
18412308 that genetic factors from HLA-DRB1 (histocompatibility antigen DR-1 beta)genotypes might be related to the susceptibility to Henoch-Schonlein purpura for Turkish children but not to the severity of this disease
18412308 Observational study of gene-disease association. (HuGE Navigator)
18408266 The results revealed a significant increase in the frequency of HLA-DRB1*04 in the patient group. This suggests that HLA-DRB1*04 is associated with the susceptibility to early childhood caries.
18408266 Observational study of gene-disease association. (HuGE Navigator)
18408250 Observational study of gene-disease association. (HuGE Navigator)
18401352 Observational study of gene-disease association. (HuGE Navigator)
18399156 Observational study of gene-disease association. (HuGE Navigator)
18398946 Observational study of gene-disease association. (HuGE Navigator)
18397187 HLA-DRB1*01 individuals may have a better ability to efficiently present myeloma-related antigens to immunocompetent cells, which could favor a better immune response against the tumor.
18397187 Observational study of gene-disease association. (HuGE Navigator)
18396213 Observational study of gene-disease association. (HuGE Navigator)
18395773 Observational study of gene-disease association. (HuGE Navigator)
18390988 Data show that HLA-DRB1*03 is a stronger genetic marker in Polyglandular autoimmunity than in monoglandular autoimmunity, foremost in those with early disease onset.
18390988 Observational study of gene-disease association. (HuGE Navigator)
18385790 Observational study of gene-disease association. (HuGE Navigator)
18381799 Observational study of gene-disease association. (HuGE Navigator)
18381784 Certain HLA alleles are found in Chinese patients with psoriasis (HLA-A*30, -Cw*06, -DR*07) and psoriatic arthritis (PsA) (HLA-B*27). Psoriasis patients with the HLA-B*27 and/or -Cw*12 may have higher risk of developing PsA.
18381784 Observational study of gene-disease association. (HuGE Navigator)
18378005 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18372357 Observational study of gene-disease association. (HuGE Navigator)
18371160 Observational study of gene-disease association. (HuGE Navigator)
18370845 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18367833 Findings suggest that HLA-DRB1 polymorphisms are related to the occurrence and disease progression of pIgAN patients in Han Chinese, with HLA-DRB1*140501 being a susceptible allele and HLA-DRB1*070101 a resistant allele.
18367833 Observational study of gene-disease association. (HuGE Navigator)
18356404 Observational study of gene-disease association. (HuGE Navigator)
18352820 HLA-DRB1 but not DQB1 may have a role in genetic predisposition to the myogenic type of Graves' orbitopathy in Brazilian patients
18352820 Observational study of gene-disease association. (HuGE Navigator)
18351579 Observational study of gene-disease association. (HuGE Navigator)
18347100 The results suggest a model whereby both HLA-DRB1 and HLA-DQA1 loci can interact simultaneously with XL9, and describe a regulatory mechanism involving the alteration of the general chromatin conformation and their regulation by CTCF.
18345414 Observational study of gene-disease association. (HuGE Navigator)
18338763 We were able to replicate the association of the IL23R variants with CD as well as HLA-DRB1*0103 with UC.
18338763 Observational study of gene-disease association. (HuGE Navigator)
18334870 Observational study of gene-disease association. (HuGE Navigator)
18332098 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18332066 Observational study of gene-disease association. (HuGE Navigator)
18331414 Observational study of gene-disease association. (HuGE Navigator)
18320121 Observational study of gene-disease association. (HuGE Navigator)
18316396 Observational study of gene-disease association. (HuGE Navigator)
18312480 results show that specific HLA haplotypes influence sickle cell anemia (SCA) osteomyelitis risk and that specific HLA types may serve as markers for identifying SCA patients at high risk for osteomyelitis
18312480 Observational study of gene-disease association. (HuGE Navigator)
18312478 Observational study of gene-disease association. (HuGE Navigator)
18309376 Study show genetic risk factors for rheumatoid arthritis are MHC that are independent of the DRB1 shared epitope alleles.
18309376 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18307784 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18301962 Observational study of gene-disease association. (HuGE Navigator)
18301070 Observational study of gene-disease association. (HuGE Navigator)
18300568 Observational study of gene-disease association. (HuGE Navigator)
18295738 HLA-DRB1 gene is a mayor factor for development of systemic lupus erythematosus in Latin Americans
18295738 Meta-analysis of gene-disease association. (HuGE Navigator)
18295677 Observational study of genotype prevalence. (HuGE Navigator)
18292987 Observational study of gene-disease association. (HuGE Navigator)
18289678 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18279373 HLA DRB1, DQB1 and insulin promoter VNTR polymorphisms: interactions and the association with adult-onset diabetes mellitus in Czech patients.
18279373 Observational study of gene-disease association. (HuGE Navigator)
18277084 Observational study of gene-disease association. (HuGE Navigator)
18275683 HLA-DRB1 alleles could act alone or in combination with other genes to confer differential susceptibility
18275683 Observational study of gene-disease association. (HuGE Navigator)
18273034 Observational study of gene-disease association. (HuGE Navigator)
18272866 Carriers of the DR15 allele with elevated anti-EBNA-1 antibody titers may have a markedly increased risk of MS.
18272866 Observational study of gene-disease association. (HuGE Navigator)
18272668 Observational study of gene-disease association. (HuGE Navigator)
18270855 Observational study of gene-disease association. (HuGE Navigator)
18267980 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18259107 Observational study of gene-disease association. (HuGE Navigator)
18258695 Observational study of gene-disease association. (HuGE Navigator)
18257894 Modifying effect of HLA haplotypes located trans to DQB1*02-DRB1*03 in celiac patients of Southern Europe.
18257894 Observational study of gene-disease association. (HuGE Navigator)
18256425 findings show presence of HLA-DRB1*04 was associated with severe malaria (OR = 2.42, 95% CI = 1.64, 3.58) in northern Gabon
18256425 Observational study of gene-disease association. (HuGE Navigator)
18252895 Specific combinations of alleles at the DRB1 locus determine the extent of haplotypic risk for type 1 diabetes.
18252895 Observational study of gene-disease association. (HuGE Navigator)
18248305 Observational study of gene-disease association. (HuGE Navigator)
18244920 We investigated the genetic polymorphisms of HLA-A, B, DRB1 alleles and haplotype frequencies in Mongols from Inner Mongolia, China.
18241227 Observational study of gene-disease association. (HuGE Navigator)
18240960 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18240242 shared epitope was associated with the greatest risk of death from cardiovascular disease with rheumatoid arthritis and inflammatory polyarthritis
18240242 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18240241 higher degree of European ancestry among African Americans with HLA-DRB1 alleles suggests that a genetic risk factor for rheumatoid arthritis was introduced into the African American population through admixture
18240241 Observational study of gene-disease association. (HuGE Navigator)
18236804 Observational study of gene-disease association. (HuGE Navigator)
18223493 No predisposition to CAID was associated to HLA-DRB1*04 or DDB4*01 alleles.
18223493 Observational study of gene-disease association. (HuGE Navigator)
18222012 Beninese origin and HLA-DRB1*09 allele were the other determinants independently associated with favorable outcome of HBV infection.
18222012 Observational study of gene-disease association. (HuGE Navigator)
18203322 no correlation between the presence of tumor and major histocompatibility complex class II DR beta 1 (HLA-DRB1)*0301 and *01) alleles was found in patients with Dermatomyositis and polymyositis
18203322 Observational study of gene-disease association. (HuGE Navigator)
18196245 Observational study of gene-disease association. (HuGE Navigator)
18186801 In this study, samples from 95 SARS patients and 403 healthy controls were typed for HLA-A, -B and -DRB1 alleles and no association was found between HLA variations and SARS.
18186801 Observational study of gene-disease association. (HuGE Navigator)
18177450 Observational study of gene-disease association. (HuGE Navigator)
18176993 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18167262 Observational study of gene-disease association. (HuGE Navigator)
18164964 Frequencies of HLA-DRB1 in normal population and in patients with acute lymphoblastic leukemia
18164964 Observational study of gene-disease association. (HuGE Navigator)
18163478 associated with CHurg Strauss syndrome
18162709 Meta-analysis of gene-disease association. (HuGE Navigator)
18162709 Rheumatoid arthritis susceptibility is determined by the combination of amino acid residues at HLA-DR beta71 and beta74, not by beta71 alone.
18156150 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18156150 HLA-DRB1 alleles are associated with susceptibility to the development of rheumatoid arthritis.
18093280 Observational study of gene-disease association. (HuGE Navigator)
18088469 The frequency of HLA-DRB1*15 genotype expression in children with aplastic anemia is significantly higher than that in normal controls, and immunosuppressive therapy shows favorable effect with high incidence of complete remission.
18088469 Observational study of gene-disease association. (HuGE Navigator)
18088468 DRB1*0901 gene may be considered as a risk marker while DRB1*1301 gene is a protective marker of aplastic anemia.
18088468 Observational study of gene-disease association. (HuGE Navigator)
18087043 Observational study of gene-disease association. (HuGE Navigator)
18087043 alleles at the HLA-DRB1 locus have roles in multiple sclerosis severity
18086267 Observational study of genotype prevalence. (HuGE Navigator)
18086264 DRB1*1613N is a DRB1 null allele.
18085998 Observational study of gene-disease association. (HuGE Navigator)
18085741 in patients with systemic lupus erythematosus, HLA-DRB1*0401 was associated with erosive arthritis
18085741 Observational study of gene-disease association. (HuGE Navigator)
18084828 Observational study of gene-disease association. (HuGE Navigator)
18082572 Observational study of genetic testing. (HuGE Navigator)
18077428 Observational study of gene-disease association. (HuGE Navigator)
18077428 HLA-DRB1 molecules containing amino acid sequence DERAA (i.e., HLA-DRB1*0103, *0402, *1102, *1103, *1301, *1302, and *1304) are associated with protection from rheumatoid arthritis in a case-control study of Dutch mothers compared to the fathers.
18071880 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18070336 Observational study of gene-disease association. (HuGE Navigator)
18070287 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18070287 study showed that HLA-DR13 allele is a strong protective genetic marker in chronic hepatitis B infection
18070207 Observational study of gene-disease association. (HuGE Navigator)
18069933 DRB1*0715 differs from DRB1*070101 in a point nucleotide mutation at codon 21 (ACG-->AAG), which produces an amino acid residue change from T to K.
18065518 Observational study of gene-disease association. (HuGE Navigator)
18064508 polymorphisms in some alleles of B and C in HLA class I genes are associated with Kawasaki disease in Korean children.
18064508 Observational study of gene-disease association. (HuGE Navigator)
18058064 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18057683 Observational study of gene-disease association. (HuGE Navigator)
18057683 immunoglobulin A deficiency in Polish population is strongly associated with HLA-B*08:DRB1*03 haplotype rather than with single alleles
18057383 Observational study of gene-disease association. (HuGE Navigator)
18057318 Observational study of gene-disease association. (HuGE Navigator)
18057318 In patient with multiple sclerosis all HLA-DRB1 risk alleles were more common in Malta, whereas HLA-DRB1*11 was slightly less common.
18053473 Observational study of gene-disease association. (HuGE Navigator)
18039812 appears to be both a risk allele for type 1 diabetes and a protective allele for nephropathy
18039812 Observational study of gene-disease association. (HuGE Navigator)
18038917 Observational study of gene-disease association. (HuGE Navigator)
18036860 Observational study of gene-disease association. (HuGE Navigator)
18036100 identification of DRB1*01 and DQB1*03 involved with self-limiting hepatitis in different ethnic groups
18032542 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18028350 Report association between the genetic polymorphism of HLA-DQA1, DQB1, and DRB1 and serum alanine aminotransferase levels in chronic hepatitis C in the Chinese population.
18028350 Observational study of gene-disease association. (HuGE Navigator)
18022727 the frequencies of DRB1 *0405 and DQB1 *0401 were significantly increased in patients with autoimmune hepatitis
18022727 Observational study of gene-disease association. (HuGE Navigator)
18022570 HLA-DRB1*09 is associated with increased incidence of cytomegalovirus infection and disease after allogeneic hematopoietic stem cell transplantation
18007983 Observational study of gene-disease association. (HuGE Navigator)
18003662 Observational study of gene-disease association. (HuGE Navigator)
18001300 Observational study of genotype prevalence. (HuGE Navigator)
18001297 Observational study of genotype prevalence. (HuGE Navigator)
18000641 Observational study of gene-disease association. (HuGE Navigator)
18000641 HLA DRB1*15 was present in 70% of multiple sclerosis affected individuals; the transmission disequilibrium test showed a significant excess in transmission of DRB1*15 alleles to affected individuals
17997607 Observational study of gene-disease association. (HuGE Navigator)
17992468 Observational study of gene-disease association. (HuGE Navigator)
17989838 Observational study of gene-disease association. (HuGE Navigator)
17989341 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17987563 Observational study of gene-disease association. (HuGE Navigator)
17982455 Observational study of gene-disease association. (HuGE Navigator)
17977208 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17977208 HLA-DRB1 *07 allele seems to be protective marker against ITP (Idiopathic thrombocytopenic purpura), HLA-DRB1 *14 allele can be used as a predictive marker for therapy, HLA-DRB1 *13 allele has an important role in resistance to therapy
17972102 Parental transmission of HLA-DRB1*15 in multiple sclerosis.
17972102 Observational study of gene-disease association. (HuGE Navigator)
17971177 Observational study of gene-disease association. (HuGE Navigator)
17971052 Observational study of gene-disease association. (HuGE Navigator)
17971048 Observational study of gene-disease association. (HuGE Navigator)
17964196 Observational study of gene-disease association. (HuGE Navigator)
17961971 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17961775 Observational study of genotype prevalence. (HuGE Navigator)
17959659 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
17956579 Observational study of gene-disease association. (HuGE Navigator)
17947711 majority of patients with Lyme arthritis initially have increased frequencies of OspA(161-175)-specific T cells
17941906 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17936227 Our results provide evidence of a role for DR5 and DQ3 HLA class II clusters and a higher frequency of HLA homozygous leading to the clinical outcome of type II mixed cryoglobulinemic autoimmune disease.
17936227 Observational study of gene-disease association. (HuGE Navigator)
17935228 Observational study of gene-disease association. (HuGE Navigator)
17928868 Observational study of gene-disease association. (HuGE Navigator)
17927716 Observational study of gene-disease association. (HuGE Navigator)
17922429 Observational study of gene-disease association. (HuGE Navigator)
17911430 Observational study of gene-disease association. (HuGE Navigator)
17911417 HLA-DRB1 SE alleles may significantly contribute to the genetic determination of anti-CCP production in Hungarian patients with RA.
17910142 Observational study of gene-disease association. (HuGE Navigator)
17907045 Observational study of gene-disease association. (HuGE Navigator)
17901090 Observational study of gene-disease association. (HuGE Navigator)
17900288 Observational study of genotype prevalence. (HuGE Navigator)
17895416 Observational study of gene-disease association. (HuGE Navigator)
17893434 Observational study of gene-disease association. (HuGE Navigator)
17891921 Observational study of genotype prevalence. (HuGE Navigator)
17878210 Observational study of gene-disease association. (HuGE Navigator)
17876645 Observational study of gene-disease association. (HuGE Navigator)
17876645 In Japanese RA patients, HLA-DRB1 SE alleles are associated with disease onset at an earlier age, as has been observed in Caucasian RA patients
17875181 Observational study of gene-disease association. (HuGE Navigator)
17869653 Observational study of genotype prevalence. (HuGE Navigator)
17845310 Observational study of gene-disease association. (HuGE Navigator)
17845076 Observational study of gene-disease association. (HuGE Navigator)
17826339 Observational study of gene-disease association. (HuGE Navigator)
17825227 HLA-A * 02, HLA-B * 58 and HLA-DRB1 * 03 might be the susceptible genes of NPC patients while HLA-B * 40 might be the protective gene of NPC patients.
17825227 Observational study of gene-disease association. (HuGE Navigator)
17785916 New HLA DRB1 and DQB1 haplotypes in a pedigree of familial Graves' disease in Japan.
17785583 Observational study of gene-disease association. (HuGE Navigator)
17767551 Observational study of gene-disease association. (HuGE Navigator)
17767551 results strongly imply that the HLA-B8, -DRB1*0301, -DQB1*0201 haplotype genetically & primarily determines predisposition to
17763436 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17763415 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17761456 This report provides a description of a multiplex KLS family with six members affected. HLA-DQB1 *02 homozygosity was present in 4/6 affected and 2/6 unaffected family members.
17728335 Observational study of gene-disease association. (HuGE Navigator)
17726164 Observational study of gene-disease association. (HuGE Navigator)
17722421 Observational study of gene-disease association. (HuGE Navigator)
17722299 Observational study of gene-disease association. (HuGE Navigator)
17722299 HLA DRB1*0301 was associated with an increased risk of autoimmune hepatitis type 1 in this study in Thailand.
17715334 Observational study of gene-disease association. (HuGE Navigator)
17714903 Observational study of gene-disease association. (HuGE Navigator)
17686102 Observational study of gene-disease association. (HuGE Navigator)
17686102 In a population of children in Norway, birch allergy was associated with DQB1*0603-DRB1*13 haplotype. Mugwort allergy was associated with DQB1*0609-DRB1*13 and DQB1*0501-DRB1*01 haplotypes. Asthma was not associated with DRB1.
17681614 The present results suggest that a given HLA-DRB1 allele may exhibit different behaviors, i.e. confer resistance or susceptibility, in response to the environmental and/or genetic (ethnic) backgrounds that characterize a sampled population.
17680546 HLA-DRB1*04 gene is one of the factors which determine the outcomes of HBV infection, while it has no influence on HBV replication.
17680546 Observational study of gene-disease association. (HuGE Navigator)
17673491 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17673320 Observational study of gene-disease association. (HuGE Navigator)
17672065 Observational study of gene-disease association. (HuGE Navigator)
17666451 Observational study of gene-disease association. (HuGE Navigator)
17665209 Observational study of gene-disease association. (HuGE Navigator)
17665209 HLA-DRB1*0101 is a marker for the development of lichen planus in Mexican Mestizo population
17662890 NOD/scid-HLA-DR1 transgenic mice were similar to the NOD/scid mice, with the exception of longer lifespan.
17662350 Observational study of gene-disease association. (HuGE Navigator)
17662002 Observational study of gene-disease association. (HuGE Navigator)
17662002 Associations between HLA-DRB1*15 and age at onset of MS were reproduced in this extended Scandinavian MS cohort.
17661910 Observational study of gene-disease association. (HuGE Navigator)
17661909 Observational study of gene-disease association. (HuGE Navigator)
17661908 Observational study of gene-disease association. (HuGE Navigator)
17660221 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17658488 DQB10602 homozygous subjects to be far more susceptible to narcolepsy.
17653770 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17653284 The combination of HLA-A and HLA-DRB1 alleles have been found to influence risk of muliple sclerosis 23-fold.
17653284 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17652849 Observational study of gene-disease association. (HuGE Navigator)
17652849 Possession of HLA-DRB1*01 increases the risk of Human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis in HTLV-I-infected individuals.
17652848 Observational study of genotype prevalence. (HuGE Navigator)
17631742 Observational study of gene-disease association. (HuGE Navigator)
17629023 Observational study of gene-disease association. (HuGE Navigator)
17622942 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17610417 Observational study of gene-disease association. (HuGE Navigator)
17610416 Meta-analysis of gene-disease association. (HuGE Navigator)
17604825 Observational study of gene-disease association. (HuGE Navigator)
17603847 Observational study of gene-disease association. (HuGE Navigator)
17592398 Observational study of gene-disease association. (HuGE Navigator)
17592398 The allele HLA-DRB1*1101 and the allelic group HLA-DRB1*11 may determine an increased susceptibility to develop bilateral Meniere's disease in a southern European population
17589850 The association of HLA-D4 antigen share epitope alleles and TNF-alpha gene polymorphism with susceptibility to rheumatoid arthritis in Thai.
17589850 Observational study of gene-disease association. (HuGE Navigator)
17588142 Observational study of gene-disease association. (HuGE Navigator)
17588142 There is a positive correlation between DR B1* 04 and goitrous juvenile autoimmune hypothyroidism.
17584771 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17584585 Observational study of gene-disease association. (HuGE Navigator)
17584581 Observational study of gene-disease association. (HuGE Navigator)
17583734 DRB3*0101 and DRB1*0301 belong to an ancestral haplotype and are associated with many autoimmune diseases linked to antigen presentation.
17578052 Observational study of gene-disease association. (HuGE Navigator)
17578051 Observational study of gene-disease association. (HuGE Navigator)
17573956 Observational study of gene-disease association. (HuGE Navigator)
17561243 The HLA-DR2 alleles DRB1(*)1501 and DRB1(*)1503 play a major role in the development of allergic pulmonary inflammation
17559688 Observational study of gene-disease association. (HuGE Navigator)
17559688 certain HLA class II haplotypes are associated with risk for or protection against RHD and that these associations are more evident in patients in clinically homogeneous groups
17559577 Observational study of gene-disease association. (HuGE Navigator)
17554341 Observational study of gene-disease association. (HuGE Navigator)
17554059 Observational study of gene-disease association. (HuGE Navigator)
17546694 Observational study of gene-disease association. (HuGE Navigator)
17543145 Observational study of gene-disease association. (HuGE Navigator)
17543145 In Japanese patients with rheumatoid arthritis, HLA-DRB1 SE alleles are associated with production of anti-cyclic citrullinated peptides antibodies.
17541908 Observational study of gene-disease association. (HuGE Navigator)
17541908 we identified associations of HLA class II alleles in SA and TB with expression pattern specific and different for each group.
17538887 Observational study of gene-disease association. (HuGE Navigator)
17537386 Meta-analysis of gene-disease association. (HuGE Navigator)
17537386 HLA-DR4 and shared epitope positive HLA-DRB1 alleles (mainly HLA-DRB10404) are associated with rheumatoid arthritis in Latin Americans [meta-analysis]
17534404 Observational study of gene-disease association. (HuGE Navigator)
17534404 study indicates that the HLA-DRB1*04 alleles, especially subtype HLA-DRB1*0405, were significantly associated with rheumatoid arthritis (RA) susceptibility in the Chinese Shantou population; HLA-DRB1*04 alleles may be associated with the severity of RA
17531857 Observational study of gene-disease association. (HuGE Navigator)
17516530 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17516530 study indicates that HLA-DRB1 polymorphism plays an important direct or indirect role in influencing the development of cervical cancer among southern Chinese, and these associations are likely to be human papillomavirus type-dependent
17513705 Observational study of gene-disease association. (HuGE Navigator)
17513705 children with DRB1*0401 (the most common DRB1*04 subtype), DPB1*0402 influences development of anti-islet autoantibodies and increases risk of type 1 diabetes.
17510796 HLA DRB1*13 may be a genetic risk factor for some white North American patients with type 1 autoimmune hepatitis.
17509453 Observational study of genotype prevalence. (HuGE Navigator)
17507489 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
17505501 Observational study and genome-wide association study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17498269 Observational study of gene-disease association. (HuGE Navigator)
17493347 Observational study of genotype prevalence. (HuGE Navigator)
17493158 a variant DRB1*13 allele, which has now been named DRB1*1371 is reported
17489940 Observational study of gene-disease association. (HuGE Navigator)
17489940 Heterogeneous phenotypes occur in both Brazilian ethnic groups: African-Brazilian and white Brazilian in multiple sclerosis
17489060 Observational study of gene-disease association. (HuGE Navigator)
17488703 Observational study of gene-disease association. (HuGE Navigator)
17469103 Observational study of gene-disease association. (HuGE Navigator)
17469097 Observational study of gene-disease association. (HuGE Navigator)
17469097 The risk of mortality due to ischemic heart disease or cancer in rheumatoid arthritis is increased in patients carrying HLA-DRB1 genotypes with particular homozygous and compound heterozygous SE combinations.
17463066 The effect of HLA-DR(2)15 and the MS immunopathic trait (MSIT) appear to be synergistic in the genetics of sporadic multiple sclerosis. The DR15 antigen is encoded by the HLA-DRB1 locus.
17463066 Observational study of gene-disease association. (HuGE Navigator)
17462511 Observational study of genotype prevalence. (HuGE Navigator)
17460569 Observational study of genotype prevalence. (HuGE Navigator)
17458393 Observational study of gene-disease association. (HuGE Navigator)
17455230 PAP (133-152) and PAP (173-192) were immunogenic and processed from whole PAP in HLA-DRB1*1501 tg mice. These peptides were capable of stimulating CD4 T lymphocytes from HLA-DRB1*1501-positive patients with granulomatous prostatitis and normal donors.
17453717 Observational study of gene-disease association. (HuGE Navigator)
17445173 Observational study of genotype prevalence. (HuGE Navigator)
17445172 Observational study of genotype prevalence. (HuGE Navigator)
17437273 Observational study of gene-disease association. (HuGE Navigator)
17436241 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17436241 Consistent interaction, defined as departure from additivity, between HLA-DRB1 SE alleles and the A allele of PTPN22 R620W was seen in all three studies regarding anti-CCP-positive rheumatoid arthritis.
17433060 Observational study of gene-disease association. (HuGE Navigator)
17431094 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
17428358 Observational study of gene-disease association. (HuGE Navigator)
17412364 Observational study of gene-disease association. (HuGE Navigator)
17412364 A higher frequency of HLA-DRB1*15 was found in MS patients (29.8% vs 19.9%, odds ratio (OR)=1.72, 95% CI=1.15-2.56, p=0.008).
17411376 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
17407088 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17406941 Observational study of gene-disease association. (HuGE Navigator)
17406941 Study found that the HLA-DRB1*0406-DQB1*0302 haplotype is associated with idiopathic pulmonary arterial hypertension in Korean patients
17406641 Observational study of gene-disease association. (HuGE Navigator)
17401504 Observational study of gene-disease association. (HuGE Navigator)
17396103 Observational study of gene-disease association. (HuGE Navigator)
17396103 HLA-DRB1*10 is associated with susceptibility to leprosy and HLA-DRB1*04 is associated with resistance, both in the Brazilian and Vietnamese populations; these alleles play a role in activation of cellular immune responses against M. leprae
17392574 Observational study of gene-disease association. (HuGE Navigator)
17392350 Observational study of gene-disease association. (HuGE Navigator)
17389015 Observational study of gene-disease association. (HuGE Navigator)
17389015 DRB1*0402 without DQB1*0302 is the most relevant HLA-DRB1 allele responsible for the pathogenesis of pemphigus in Venezuelan patients with pemphigus vulgaris
17389014 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17389014 there is an epistatic interaction between genes in chromosomes 6p21 and 1q21-22, marked, respectively, by HLA-DRB1*0103 and FCRL3-169 AG
17389012 Observational study of gene-disease association. (HuGE Navigator)
17389012 DRB1*15-DQB1*06 haplotype in the Sami population may have a role in the low prevalence of multiple sclerosis
17388766 Observational study of gene-disease association. (HuGE Navigator)
17387388 Observational study of gene-disease association. (HuGE Navigator)
17387388 The most frequent haplotypes in our CML patients were HLA-DRB1*11/-DQB1*03011/-DQA1*0505 (P=0.01) and HLA-DRB1*04/-DQB1*0302/-DQA1*03011 (P=0.02).
17384941 describe the identification of the novel human leukocyte antigen (HLA) blank allele DRB1*0710N that was detected in a male individual of Caucasian origin
17383044 Observational study of gene-disease association. (HuGE Navigator)
17383044 Two HLA risk haplotypes in PSC (carrying DRB1*0301 or DRB1*1501, respectively) were devoid of both of these alleles, and carried the 5.1 variant of the major HLA I chain-related A (MICA) gene previously reported to influence PSC susceptibility.
17378697 Observational study of gene-disease association. (HuGE Navigator)
17376212 Observational study of gene-disease association. (HuGE Navigator)
17376212 HLA-DRB1 alleles seem to be involved in the genetic susceptibility to CDLE in the Mexican mestizo population.
17364902 relationships among longevity, diseases, and HLA-DRB1/DQB1 allelic polymorphisms
17350686 Observational study and meta-analysis of gene-disease association and gene-gene interaction. (HuGE Navigator)
17349874 Observational study of gene-disease association. (HuGE Navigator)
17345114 Investigatation of the evolutionary history of the HLA-DRB1 locus on the basis of an analysis of 15 genomic full-length alleles.
17341507 Observational study of gene-disease association. (HuGE Navigator)
17341285 Observational study of gene-disease association. (HuGE Navigator)
17341285 increased frequency of HLA-DRB1*08 and a decreased frequency of HLA-DRB1*04 in the group with type 2 diabetes mellitus vs. type 1 diabetes mellitus
17334650 Observational study of gene-disease association. (HuGE Navigator)
17329717 Meta-analysis and HuGE review of gene-disease association. (HuGE Navigator)
17329717 literature reviewed for an association between the DRB1*1501-DQA1*0102-DQB1*0602 haplotype(DR15)and multiple sclerosis; in most papers, a higher frequency of the DR15 haplotype and/or its component alleles among MS cases than among controls was reported
17328818 Observational study of gene-disease association. (HuGE Navigator)
17325942 Observational study of gene-disease association. (HuGE Navigator)
17324966 Observational study of gene-disease association. (HuGE Navigator)
17324966 HLA-DRB1*0404 is strongly associated with anticalpastatin antibodies in rheumatoid arthritis.
17318773 Observational study of gene-disease association. (HuGE Navigator)
17318773 HLA DRAB1 polymorphism in type 1 diabetes mellitus.
17311339 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17311253 Observational study of gene-disease association. (HuGE Navigator)
17310371 Observational study of gene-disease association. (HuGE Navigator)
17309450 Observational study of gene-disease association. (HuGE Navigator)
17309132 Observational study of gene-disease association. (HuGE Navigator)
17309132 results show that shared epitope-encoding HLA-DRB1*0405 and *1001 are associated with rheumatoid arthritis in a Taiwanese population
17306585 Observational study of genotype prevalence. (HuGE Navigator)
17305280 Observational study of gene-disease association. (HuGE Navigator)
17304884 Observational study of gene-disease association. (HuGE Navigator)
17301827 Observational study of gene-disease association. (HuGE Navigator)
17299710 Observational study of gene-disease association. (HuGE Navigator)
17294607 Observational study of gene-disease association. (HuGE Navigator)
17288808 Observational study of genotype prevalence. (HuGE Navigator)
17287608 Observational study of gene-disease association. (HuGE Navigator)
17285557 DR7 and DR11 alleles of HLA-DRB1 are probably susceptible genes of type 2 diabetes mellitus in Yunnan Yi nationality.
17285557 Observational study of gene-disease association. (HuGE Navigator)
17285554 Results show that DR7 allele of HLA-DRB1 gene might be the protective gene of Keshan disease.
17285554 Observational study of gene-disease association. (HuGE Navigator)
17284224 Observational study of gene-disease association. (HuGE Navigator)
17284224 The frequencies of DRB1*03 was significantly increased in GD compared to controls, whereas DRB1*13 and DRB1*07 were significantly increased in controls compared to patients.
17284220 We report the identification of a novel HLA-DRB1*04, officially named DRB1*0460.
17266100 Observational study of gene-disease association. (HuGE Navigator)
17266100 Increased risk of cardiovascular events (CV) was associated with CRP level, ESR, and HLA-DRB1, suggesting high inflammatory response in genetically predisposed individuals promotes an increased risk of CV events and mortality in rheumatoid arthritis.
17265477 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17265477 HLA-DRB1 shared epitope (SE) subtypes differ in interaction with smoking and in predisposition to anti-cyclic citrullinated peptide (CCP) antibodies. Tobacco exposure contributes to development of rheumatoid arthritis in SE+, anti-CCP+ patients.
17257320 Observational study of gene-disease association. (HuGE Navigator)
17257320 HLA-DRB1*03 and HLA-DRB1*07 are related to susceptibility to chronic HBV infection, and DRB1*15 is negatively related to persistence to chronic HBV infection among people in northwestern China.
17257319 Observational study of gene-disease association. (HuGE Navigator)
17257318 Observational study of genotype prevalence. (HuGE Navigator)
17256150 Observational study of gene-disease association. (HuGE Navigator)
17252545 Observational study of gene-disease association. (HuGE Navigator)
17237562 Observational study of gene-disease association. (HuGE Navigator)
17234427 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17227111 Observational study of gene-disease association. (HuGE Navigator)
17223660 Observational study of gene-disease association. (HuGE Navigator)
17215337 Observational study of gene-disease association. (HuGE Navigator)
17212710 Observational study of genotype prevalence. (HuGE Navigator)
17212707 Observational study of gene-disease association. (HuGE Navigator)
17212706 Observational study of gene-disease association. (HuGE Navigator)
17207714 Observational study of gene-disease association. (HuGE Navigator)
17207714 Susceptibility to Kawasaki disease and coronary artery lesions is not associated with the HLA-DRB1 gene in a Taiwanese population.
17207713 There are predisposing effects of the DQB1*0301 allele and protective effects for DQA1*0103-DQB1*0601 with regard to narcolepsy.
17207378 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17198869 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17198869 Although both DRB1( *)1501 and DRB1( *)1502 contribute to the development of aplastic anemia, the methods of contribution differ between the two alleles.
17186951 Observational study of gene-disease association. (HuGE Navigator)
17186951 The frequency of HLA-DRB1*12 was significantly higher in the Persistent group than in the Recovered group (P=0.004)of hepatitis B virus infections.
17182961 Observational study of gene-disease association. (HuGE Navigator)
17180363 Observational study of gene-disease association. (HuGE Navigator)
17153701 Observational study of gene-disease association. (HuGE Navigator)
17144392 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17143607 Observational study of gene-disease association. (HuGE Navigator)
17143607 Patterns of susceptibility at the HLA-DRB1 and HLA-DQB1 loci in latent autoimmune diabetes in adults are similar to those reported for type 1 diabetes.
17133612 Observational study of gene-disease association. (HuGE Navigator)
17130569 Observational study of gene-disease association. (HuGE Navigator)
17130566 Observational study of gene-disease association. (HuGE Navigator)
17130528 Observational study of genotype prevalence. (HuGE Navigator)
17126830 Observational study of gene-disease association. (HuGE Navigator)
17124999 Observational study of gene-disease association. (HuGE Navigator)
17119950 Observational study of gene-disease association. (HuGE Navigator)
17119950 The two critical HLA regions for susceptibility to autoimmune pancreatitis are limited to the HLA-DRB1*0405-DQB1*0401 in the class II and the ABCF1in the class I regions.
17116345 Observational study of gene-disease association. (HuGE Navigator)
17113829 HLA-DRbeta1*0402 tetramers provide a highly specific approach to monitor ex vivo the T cellular autoimmune response against desmoglein-3 in patients with pemphigus vulgaris.
17106689 Observational study of gene-disease association. (HuGE Navigator)
17106689 HLA-DRB1* 03011, and possibly 1105, alleles confer susceptibility to POST-STREPTOCOCCAL ACUTE GLOMERULONEPHRITIS
17106278 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
17105585 Observational study of gene-disease association. (HuGE Navigator)
17092866 Observational study of genotype prevalence. (HuGE Navigator)
17086601 Observational study of gene-disease association. (HuGE Navigator)
17086601 data suggest that presence of double HLA-DRB1*04 shared epitope is associated with a higher risk of developing AA amyloidosis in Japanese patients with RA
17075829 shared epitope can trigger NO-mediated signaling events in opposite cells, and may thereby contribute to rheumatoid arthritis pathogenesis.
17075818 African Americans with dermatomyositis or with anti-Jo-1 autoantibodies shared the risk factor HLA-DRB1*0301 with European Americans
17074598 Observational study of gene-disease association. (HuGE Navigator)
17060025 Observational study of gene-disease association. (HuGE Navigator)
17056584 Alternative DSG1 isoform bears a specific peptide sequence that binds to the pemphigus foliaceus associated HLA class II DRbeta1*0102 molecule.
17055527 Observational study of genetic testing. (HuGE Navigator)
17054449 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17050030 Observational study of gene-disease association. (HuGE Navigator)
17047287 Observational study of gene-disease association. (HuGE Navigator)
17028803 Observational study of gene-disease association. (HuGE Navigator)
17026471 Observational study of genotype prevalence. (HuGE Navigator)
17026464 Observational study of genotype prevalence. (HuGE Navigator)
17026463 Observational study of gene-disease association. (HuGE Navigator)
17021767 Observational study of gene-disease association. (HuGE Navigator)
17016821 Observational study of gene-disease association. (HuGE Navigator)
17003176 Observational study of gene-disease association. (HuGE Navigator)
17003171 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17002906 Observational study of gene-disease association. (HuGE Navigator)
17002902 Observational study of gene-disease association. (HuGE Navigator)
16988007 Observational study of gene-disease association. (HuGE Navigator)
16973583 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
16972006 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16966600 Observational study of gene-disease association. (HuGE Navigator)
16964961 Observational study of gene-disease association. (HuGE Navigator)
16964961 Slovak patients with type 1A diabetes mellitus were typed for class II HLA genes. Among 13 HLA-DRB1 alleles tested, the most common occurrence rates showed DRB1*03 and DRB1*04, while the least frequent alleles were DRB 1*15, DRB1*07, and DRB1*11.
16960929 Observational study of gene-disease association. (HuGE Navigator)
16948649 Observational study of gene-disease association. (HuGE Navigator)
16941709 Observational study of gene-disease association. (HuGE Navigator)
16941709 a complex relationship exists between HLA and PBC, and some genetic associations may be population specific.
16935791 Observational study of gene-disease association. (HuGE Navigator)
16935351 Observational study of gene-disease association. (HuGE Navigator)
16923796 Observational study of gene-disease association. (HuGE Navigator)
16916662 Observational study of gene-disease association. (HuGE Navigator)
16905561 Observational study of gene-disease association. (HuGE Navigator)
16905561 Results derived from analyses of 1339 MS families indicate DRB1 variation influences MS susceptibility in a complex manner.
16890179 Observational study of gene-disease association. (HuGE Navigator)
16887863 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16884876 Observational study of genotype prevalence. (HuGE Navigator)
16883532 Individuals with different haplotypes composed of HLA-DRB1 and HLA-DQA1 might have different outcomes of HBV infection.
16883532 Observational study of gene-disease association. (HuGE Navigator)
16879749 Observational study of gene-disease association. (HuGE Navigator)
16879301 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16875346 Observational study of gene-disease association. (HuGE Navigator)
16872485 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16866885 Observational study of genotype prevalence. (HuGE Navigator)
16866883 Observational study of genotype prevalence. (HuGE Navigator)
16857416 Observational study of gene-disease association. (HuGE Navigator)
16855621 Observational study of gene-disease association. (HuGE Navigator)
16855521 Observational study of gene-disease association. (HuGE Navigator)
16849401 Observational study of gene-disease association. (HuGE Navigator)
16846526 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16829512 Crystal structure of staphylococcal enterotoxin I (SEI) in complex with DR1 beta
16829309 Observational study of genotype prevalence. (HuGE Navigator)
16829307 Observational study of gene-disease association. (HuGE Navigator)
16826237 Observational study of gene-disease association. (HuGE Navigator)
16826237 Rheumatoid arthritis patients and controls were genotyped for 12 alleles of the HLA-DRB1 locus, models were used to assess the role of the shared epitope (SE) and of its individual components and SE was found to be associated with RA susceptibility.
16815190 Observational study of gene-disease association. (HuGE Navigator)
16802776 Observational study of gene-disease association. (HuGE Navigator)
16799707 Observational study of gene-disease association. (HuGE Navigator)
16799707 Comparison of allele and haplotype distribution between patients and 70 female control subjects reveals a negative association between HLADRB1* 07-DQB1*02 and the incidence of breast cancer in the Tunisian population.
16796128 Observational study of gene-disease association. (HuGE Navigator)
16793843 Observational study of gene-disease association. (HuGE Navigator)
16792590 Observational study of gene-disease association. (HuGE Navigator)
16786764 Observational study of gene-disease association. (HuGE Navigator)
16778420 Observational study of gene-disease association. (HuGE Navigator)
16773677 This article reviews current knowledge of the role of HLA complex genes in IBD susceptibility and phenotype, and discusses the factors currently limiting the translation of this knowledge to clinical practice.
16769963 Observational study of gene-disease association. (HuGE Navigator)
16767683 The HLA-DRB1 polymorphism of Liaoning Han populations show the special characters and HLA-DRB1 genotyping is useful genetic marker to paternity testing and personal identification.
16767683 Observational study of genotype prevalence. (HuGE Navigator)
16756466 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16756466 CTLA-4 acts in the predisposition to Graves' disease by switching off the protective DRB1*07 influence, whereas DRB1*03 has an independent effect
16733891 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16731854 Observational study of gene-disease association. (HuGE Navigator)
16720214 Observational study and meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
16720214 Meta-analysis confirms the apparent association between certain HLA-DRB1 allele families and alleles and cervical squamous cell carcinoma.
16720213 Observational study of gene-disease association. (HuGE Navigator)
16720210 Observational study of gene-disease association. (HuGE Navigator)
16714073 Observational study of gene-disease association. (HuGE Navigator)
16712649 Observational study of genotype prevalence. (HuGE Navigator)
16709874 Observational study of gene-disease association. (HuGE Navigator)
16709874 A post hoc age- and sex-stratified analysis reveals lower schistosomiasis reinfection intensities at 1 year, 22 mo, and 6 years after the first round of treatment among genetic carriers of HLA-DRB1*13.
16704757 Observational study of gene-disease association. (HuGE Navigator)
16700999 Observational study of gene-disease association. (HuGE Navigator)
16698432 No allelic HLA or 5-HTTLPR polymorphisms were specifically associated with autism spectrum disorders.
16689106 Observational study of genotype prevalence. (HuGE Navigator)
16673133 Observational study of gene-disease association. (HuGE Navigator)
16673133 This study examines the frequency of HLA-DRB1 alleles amongst Saudi RA patients
16671949 Observational study of gene-disease association. (HuGE Navigator)
16646982 Observational study of gene-disease association. (HuGE Navigator)
16646982 association between the HLA-DRB1 gene and rheumatoid arthritis, and linkage data for that gene and validity of results.
16646680 Observational study of gene-disease association. (HuGE Navigator)
16646680 results may suggest interaction between the DRbeta1 chain R genotype & thyroglobulin CC genotype in conferring susceptibility to Graves disease; these results, if confirmed, may imply that these variants interact biologically to increase the odds of GD
16629714 Observational study of gene-disease association. (HuGE Navigator)
16611259 Observational study of gene-disease association. (HuGE Navigator)
16611256 Observational study of gene-disease association. (HuGE Navigator)
16609350 Observational study of gene-disease association. (HuGE Navigator)
16606409 Observational study of gene-disease association. (HuGE Navigator)
16604510 Observational study of genotype prevalence. (HuGE Navigator)
16584643 Observational study of gene-disease association. (HuGE Navigator)
16573562 Observational study of gene-disease association. (HuGE Navigator)
16572446 Observational study of gene-disease association. (HuGE Navigator)
16572445 Observational study of gene-disease association. (HuGE Navigator)
16566202 Observational study of gene-disease association. (HuGE Navigator)
16555323 DR13-related immune responses may play a role in mediating graft loss in hepatitis B and primary sclerosing cholangitis liver transplantations.
16540751 Observational study of gene-disease association. (HuGE Navigator)
16537577 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16533342 Observational study of gene-disease association. (HuGE Navigator)
16532100 Observational study of gene-disease association. (HuGE Navigator)
16530511 Observational study of gene-disease association. (HuGE Navigator)
16518608 Lyme arthritis with persistent synovitis found in association with HLA-DRB1*1104 in children.
16507114 Observational study of gene-disease association. (HuGE Navigator)
16496287 Observational study of gene-disease association. (HuGE Navigator)
16495319 Observational study of gene-disease association. (HuGE Navigator)
16490755 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16481299 Observational study of gene-disease association. (HuGE Navigator)
16473309 Observational study of genotype prevalence. (HuGE Navigator)
16467040 Observational study of gene-disease association. (HuGE Navigator)
16467040 The HLA-DRB1*15 allele was associated with the development of systemic sclerosis in Korea.
16463424 Observational study of gene-disease association. (HuGE Navigator)
16463424 The strong association between chronic periaortitis and HLA-DRB1*03, linked to a wide range of autoimmune conditions, further supports the view that CP may represent a clinical manifestation of an autoimmune disease.
16456803 Observational study of genotype prevalence. (HuGE Navigator)
16456799 Observational study of genotype prevalence. (HuGE Navigator)
16456797 Observational study of genotype prevalence. (HuGE Navigator)
16453260 Observational study of gene-disease association. (HuGE Navigator)
16451208 Observational study of gene-disease association. (HuGE Navigator)
16451199 Observational study of genotype prevalence. (HuGE Navigator)
16447236 Observational study of gene-disease association. (HuGE Navigator)
16441502 Identification of a novel HLA-DRB1*11 allele: DRB1*1152
16441501 Identification of a novel HLA-DRB1*09 allele, DRB1*0904
16441489 Family segregation analysis revealed that the HLA-DQB1*0627 allele belongs to the haplotype A*0101, B*1517, Cw*0701, DRB1*1302, DQB1*0627. The donor phenotype is HLA-A*0101; B*0801,*1517; Cw*0701; DRB1*1302,*1501; DQB1*0602,*0627.
16441488 Observational study of genotype prevalence. (HuGE Navigator)
16441488 Among 24 DRB1 alleles detected, DRB1*150101, DRB1*140101, DRB1*160201 and DRB1*090102 in Miao and DRB1*120201, DRB1*140101, DRB1*150101 and DRB1*090102 in Yao were highly predominant.
16441486 Observational study of genotype prevalence. (HuGE Navigator)
16441486 Gene frequencies and haplotypic associations within HLA-A loci were determined at a high-resolution allelic level and should provide useful information in anthropology, bone marrow donor registry, legal medicine, and disease association studies.
16438485 The association with the HLA-DRB1 gene is the best understood, although several non-HLA loci have been linked to RA.
16437632 Meta-analysis of gene-disease association. (HuGE Navigator)
16433795 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16430717 Observational study of gene-disease association. (HuGE Navigator)
16426242 Observational study of gene-disease association. (HuGE Navigator)
16426242 For class II antigens, RHD patients had higher frequencies for HLA-DRB1*01, DRB1*04 , DRB1*07 and HLA-DQB1*02 without reaching statistical significance, and significantly lower frequencies for DRB1*13, DRB5* and DRB3* compared to controls.
16426241 Observational study of gene-disease association. (HuGE Navigator)
16426241 HLA-DRB1 alleles showed no strong association with UC, and no HLA-DRB1 alleles or genotypes were strongly associated with clinical subgroups of UC in Chinese patients.
16426240 We report here a novel human leukocyte antigen (HLA) allele, DRB1*1449, in the Han-Chinese population. This novel allele might be a result of recombination between DRB1*1402 and DRB1*140101 like alleles
16420246 Observational study of gene-disease association. (HuGE Navigator)
16417614 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16409303 Observational study of gene-disease association. (HuGE Navigator)
16405603 Observational study of gene-disease association. (HuGE Navigator)
16390391 Observational study of gene-disease association. (HuGE Navigator)
16390391 In patients with slowly progressing IDDM, the DRB1*0405 frequency was increased, but the DRB1*0901 frequency was not.
16390390 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16390390 younger individuals with HLA-DRB1*0301/DRB1*04 and INS I/I genotypes exhibited increased susceptibility to type 1 diabetes mellitus
16386651 Observational study of genotype prevalence. (HuGE Navigator)
16386650 Observational study of gene-disease association. (HuGE Navigator)
16386648 Observational study of gene-disease association. (HuGE Navigator)
16386646 Observational study of gene-disease association. (HuGE Navigator)
16385499 Observational study of gene-disease association. (HuGE Navigator)
16366416 Observational study of gene-disease association. (HuGE Navigator)
16366416 The sum of susceptibility HLA-DRB1*04 alleles studied by resolution typing was strongly related to rheumatoid arthritis in the study group in comparison with the control group.
16365741 Observational study of gene-disease association. (HuGE Navigator)
16362659 Observational study of gene-disease association. (HuGE Navigator)
16362659 in Italian patients, migraine is associated with different alleles of the HLA-DRB1 locus
16361713 Observational study of gene-disease association. (HuGE Navigator)
16358956 Observational study of gene-disease association. (HuGE Navigator)
16356649 Observational study of gene-disease association. (HuGE Navigator)
16356649 The frequency of DRB1*16 allele was found to be significantly increased in migraine without aura patients
16352685 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16343061 Observational study of gene-disease association. (HuGE Navigator)
16337001 Observational study of genotype prevalence. (HuGE Navigator)
16321988 Observational study of gene-disease association. (HuGE Navigator)
16321988 Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.
16320316 Observational study of gene-disease association. (HuGE Navigator)
16320316 The HLA-DRB1 shared epitope is strongly associated with the production of anti-CCP antibodies, but not rheumatoid factor
16320082 Observational study of gene-disease association. (HuGE Navigator)
16320082 Haplotype analysis showed that DRB1*15, DQB1*0602 haplotypes carrying D6S265*15 have a ten-fold higher odds ratio (OR) than those carrying other alleles and thus confer reduced protection from type 1 diabetes mellitus.
16314951 Observational study of gene-disease association. (HuGE Navigator)
16303674 Observational study of gene-disease association. (HuGE Navigator)
16303674 Patient with HLA-DRB1 phenotype are genetically susceptible for sudden sensorineural hearing loss.
16297186 Observational study of gene-disease association. (HuGE Navigator)
16292086 Observational study of gene-disease association. (HuGE Navigator)
16286957 Observational study of genetic testing. (HuGE Navigator)
16279844 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16277897 Observational study of gene-disease association. (HuGE Navigator)
16277843 Observational study of gene-disease association. (HuGE Navigator)
16277691 Observational study of gene-disease association. (HuGE Navigator)
16276008 Observational study of gene-disease association. (HuGE Navigator)
16269080 Observational study of gene-disease association. (HuGE Navigator)
16267776 Observational study of gene-disease association. (HuGE Navigator)
16267776 DRB1*0101 allele and the DRB1*0101-DQB1*0501 haplotype may be relevant to the development of infection with strains from the least invasive genotypes of B. burgdorferi
16267409 Observational study of gene-disease association. (HuGE Navigator)
16263823 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16261886 Observational study of gene-disease association. (HuGE Navigator)
16258157 Observational study of genetic testing. (HuGE Navigator)
16255021 Observational study of gene-disease association. (HuGE Navigator)
16255019 Observational study of gene-disease association. (HuGE Navigator)
16254435 Observational study of gene-disease association. (HuGE Navigator)
16249228 Observational study of gene-disease association. (HuGE Navigator)
16245224 Observational study of gene-disease association. (HuGE Navigator)
16237774 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16226480 Observational study of gene-disease association. (HuGE Navigator)
16226480 in Kuwaiti patients, RA is associated with the presence of DRB1*04 allele.
16215957 The HLA-A,-B,-DRB1 distribution in Shanxi Han population shares some genetic characteristics with other Han populations in northern part of China, but it exhibits its own characteristics.
16215957 Observational study of genotype prevalence. (HuGE Navigator)
16215732 Observational study of genetic testing. (HuGE Navigator)
16208405 Observational study of gene-disease association. (HuGE Navigator)
16201295 Observational study of gene-disease association. (HuGE Navigator)
16201295 chronic urticaria was found strongly associated with HLA-DRB1 * 12, * 0901; the former might be the genetic markers for susceptibility
16200610 Observational study of gene-disease association. (HuGE Navigator)
16198136 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16188937 MHC-class-II molecules overcome ER retention and prevent COPI binding to the Iip35 RXR motif through a mechanism distinct from steric hindrance by its beta chain
16188098 HLA-DRB1*08 allele may be the susceptible risk gene for pneumoconiosis.
16188098 Observational study of gene-disease association. (HuGE Navigator)
16186814 Observational study of gene-disease association. (HuGE Navigator)
16185329 Observational study of gene-disease association. (HuGE Navigator)
16180280 Observational study of gene-disease association. (HuGE Navigator)
16174649 Observational study of gene-disease association. (HuGE Navigator)
16173256 Observational study of gene-disease association. (HuGE Navigator)
16158194 Observational study of gene-disease association. (HuGE Navigator)
16157380 Observational study of gene-disease association. (HuGE Navigator)
16155070 Observational study of gene-disease association. (HuGE Navigator)
16155070 Susceptibility of advanced endometriosis is not associated with HLA-DRB1 alleles in a Korean population, which is apparently not the case in the Japanese population.
16148166 Observational study of gene-disease association. (HuGE Navigator)
16143070 HLA-DR15 alleles in Han population, Gansu province seem to contribute to the genetic susceptibility, while HLA-A11 and -DR03 alleles to the genetic resistance, to leukemia.
16143070 Observational study of gene-disease association. (HuGE Navigator)
16142711 Observational study of gene-disease association. (HuGE Navigator)
16142706 Observational study of gene-disease association. (HuGE Navigator)
16133177 Observational study of gene-disease association. (HuGE Navigator)
16130422 HLA haplotypes from the sick parents who carry the specificities of HLA DRB1 13 and/or DRb1 14 are more frequently transmitted to sick children than to healthy ones.
16126967 Observational study of gene-disease association. (HuGE Navigator)
16122986 Observational study of gene-disease association. (HuGE Navigator)
16118124 Observational study of genotype prevalence. (HuGE Navigator)
16116311 Observational study of gene-disease association. (HuGE Navigator)
16112030 Observational study of gene-disease association. (HuGE Navigator)
16112030 Study provides evidence that the combination DQB1*0602/DRB1*150101 is a strong positive marker for severe pulmonary sarcoidosis.
16112029 Observational study of gene-disease association. (HuGE Navigator)
16112029 Observations emphasize the importance of the DRB1*0103-DQA1*0101-DQB1*0501 haplotype as a strong candidate for susceptibility to bee venom antigen phospholipase A2 hypersensitivity.
16107953 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16107511 Observational study of gene-disease association. (HuGE Navigator)
16103458 Observational study of gene-disease association. (HuGE Navigator)
16101839 identification of a novel human leucocyte antigen-DRB1*16 (HLA-DRB1*16) allele (DRB1*1609) by sequencing-based typing (SBT) in Chinese Han population
16101838 identification of a novel DRB1 allele, DRB1*1368
16101833 Observational study of genotype prevalence. (HuGE Navigator)
16098233 We conclude that HLA-DPGlu69 is the primary marker of Be-hypersensitivity and HLA-DRPhe47 is associated with BH in Glu69-negative subjects, likely playing a role in Be-presentation and sensitization.
16096857 Observational study of gene-disease association. (HuGE Navigator)
16096810 Observational study of gene-disease association. (HuGE Navigator)
16095118 Observational study of gene-disease association. (HuGE Navigator)
16095006 Observational study of gene-disease association. (HuGE Navigator)
16094724 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16086295 Guangdong Han population in China has twelve HLA-A, 23 B, 11 Cw and 13 DRB1 alleles and a total of 9 HLA-A-B, 20 Cw-B, 7 A-Cw, and 8 A-DRB1, 9 B-DRB1, 10 Cw-DRB1 haplotypes.
16086294 In a northwest Chinese Han population, fifteen alleles for the locus HLA-A, 28 alleles for the HLA-B locus and 13 alleles for the HLA-DRB1 were detected. The results showed that the most frequent HLA alleles found were A02, B13, and DRB1*15.
16053028 Observational study of gene-disease association. (HuGE Navigator)
16049290 Observational study of gene-disease association. (HuGE Navigator)
16042197 Observational study of gene-disease association. (HuGE Navigator)
16029431 Observational study of genetic testing. (HuGE Navigator)
16026587 a novel allele sequenced from a Han Chinese population; this allele differed by one nucleotide from DRB1*150101 at position 220 (G-->A), resulting in an amino acid substitution from Gly to Arg at codon 45
16025255 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16019679 Observational study of gene-disease association. (HuGE Navigator)
16014670 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16014635 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16011982 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16007032 Observational study of gene-disease association. (HuGE Navigator)
16007032 HLA-DRB1 polymorphism associated with genetic susceptibility of giant cell arteritis.
16005527 Observational study of gene-disease association. (HuGE Navigator)
16005098 Observational study of gene-disease association. (HuGE Navigator)
16005081 Observational study of gene-disease association. (HuGE Navigator)
15993720 Observational study of gene-disease association. (HuGE Navigator)
15993714 Observational study of gene-disease association. (HuGE Navigator)
15985473 Observational study of gene-disease association. (HuGE Navigator)
15982265 analysis of new allele HLA-DRB1*1366*
15982264 analysis of novel allele HLA-DRB1*111902*
15982256 results of this study do not support a role for an excess maternal - fetal HLA-DRB1 compatibility in multiple sclerosis susceptibility
15982255 Observational study of genotype prevalence. (HuGE Navigator)
15982255 analysis of polymorphisms in HLA-DRB1, HLA-DQB1, and HLA-DPB1 genes in the Shandong Han population
15982254 Observational study of genotype prevalence. (HuGE Navigator)
15975271 Observational study of gene-disease association. (HuGE Navigator)
15969672 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15958261 Observational study of gene-disease association. (HuGE Navigator)
15952133 The HLA-A loci are highly polymorphic in Monba population of Xizang Autonomous Region. Compared with other ethnic groups in China, the Monba ethnic group is close to Tibetan ethnic group.
15943829 Observational study of gene-disease association. (HuGE Navigator)
15941540 Observational study of gene-disease association. (HuGE Navigator)
15935893 Observational study of gene-disease association. (HuGE Navigator)
15935893 The frequency of D(70) and E(71) polymorphic residues of the DRB1 alleles was significantly reduced in epithelial ovarian cancer patients versus controls, suggesting a protective role against the disease.
15934994 Observational study of gene-disease association. (HuGE Navigator)
15932622 Observational study of genotype prevalence. (HuGE Navigator)
15929613 Observational study of gene-disease association. (HuGE Navigator)
15908298 Observational study of gene-disease association. (HuGE Navigator)
15908298 HLA-DRB1 haplotypes are associated in patients diagnosed with psoriasis vulgaris.
15906352 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15902698 Observational study of gene-disease association. (HuGE Navigator)
15901902 Observational study of gene-disease association. (HuGE Navigator)
15898419 Observational study of genotype prevalence. (HuGE Navigator)
15896210 identification of novel allele HLA-DRB1*1212
15896200 analysis of coding sequences and haplotypic associations of HLA-B and HLA-DRB1 and association to HLA-DRB3 and HLA-DRB4 loci
15885635 Observational study of gene-disease association. (HuGE Navigator)
15881283 Observational study of gene-disease association. (HuGE Navigator)
15863864 Genetic predisposition for pemphigus vulgaris seems to be one of the etiopathogenetic factor of this disease.
15858601 Observational study of gene-disease association. (HuGE Navigator)
15856071 Observational study of gene-disease association. (HuGE Navigator)
15854278 Observational study of gene-disease association. (HuGE Navigator)
15853910 HLA-DRB1*0112,a new variant, has a replacement mutation (G-->T) at nucleotide position 202 of exon 2, resulting in the AA substitution Arg-->Leu at position 72, which is not involved in peptide binding or T-cell interaction.
15853903 Observational study of gene-disease association. (HuGE Navigator)
15853901 Observational study of genetic testing. (HuGE Navigator)
15853900 Observational study of gene-disease association. (HuGE Navigator)
15853898 Observational study of genotype prevalence. (HuGE Navigator)
15851575 Observational study of gene-disease association. (HuGE Navigator)
15849775 Observational study of gene-disease association. (HuGE Navigator)
15849775 HLA-DRB1 locus does not play a significant role in the pathogenesis of avascular necrosis of the femoral head in Kuwaiti patients.
15846589 Observational study of gene-disease association. (HuGE Navigator)
15834022 Observational study of gene-disease association. (HuGE Navigator)
15833172 HLA-DRB1 * 12 and HLA-DQB1 * 0301 gene may be associated with protection against Helicobacter pylori (Hp) infection in Kunming Yi ethnic group children.
15833172 Observational study of gene-disease association. (HuGE Navigator)
15825968 Observational study of gene-disease association. (HuGE Navigator)
15825968 Elevated systolic blood pressure (SBP) was associated with HLA-DRB1*09. DRB1*107 alleles were associated with increased relative risk for elevated total cholesterol to high-density lipoprotein (HDL) ratios.
15789899 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15789899 HLA DQA1*03 allele may be a protecting factor in Turkish children with rheumatic fever. The combination of the DRB1*04 and DQA1*03 alleles may be a stronger protective factor than the DQA1*03 allele alone.
15786423 Observational study of gene-disease association. (HuGE Navigator)
15786423 degree of beta-cell destruction at diagnosis of type I diabetes is independently associated with both, age of onset and HLA genotypes
15785242 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15785242 HLA-DRB1*03 allele to be associated with Graves dosease/
15784911 HIV-1 Nef cloned from subjects with early/acute progressive HIV infection downregulates HLA-DR in 721.221 cells to a greater extent relative to HIV-1 Nef cloned from subjects with chronic progressive infection
15784468 Observational study of gene-disease association. (HuGE Navigator)
15784113 Observational study of gene-disease association. (HuGE Navigator)
15770496 Observational study of gene-disease association. (HuGE Navigator)
15763345 The most influential gene on type 1 autoimmune hepatitis pathogenesis in Japanese is the HLA-DRB1
15750822 Observational study of gene-disease association. (HuGE Navigator)
15747244 Observational study of gene-disease association. (HuGE Navigator)
15743917 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15735807 Observational study of gene-disease association. (HuGE Navigator)
15735647 Observational study of gene-disease association. (HuGE Navigator)
15734871 Observational study of gene-disease association. (HuGE Navigator)
15730926 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15730527 A novel HLA-DRB1*09 allele, HLA-DRB1*090103, has been identified in a Guangdong Han person.
15728986 Observational study of gene-disease association. (HuGE Navigator)
15728986 A study evaluating the associations between HLA alleles and the severity of malaria in a Thai population, polymorphisms of HLA-B and HLA-DRB1 genes were investigated in 472 adult patients in northwest Thailand with P. falciparum malaria.
15719619 Observational study of gene-disease association. (HuGE Navigator)
15713222 Observational study of gene-disease association. (HuGE Navigator)
15713215 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15713215 Single nucleotide polymorphisms of HLA-DRB1 is associated with Lofgren's syndrome in Czech patients with sarcoidosis
15712014 Observational study of gene-disease association. (HuGE Navigator)
15703957 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15703453 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15699512 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15699400 Observational study of gene-disease association. (HuGE Navigator)
15696102 Observational study of gene-disease association. (HuGE Navigator)
15690658 Observational study of gene-disease association. (HuGE Navigator)
15688398 Downregulation of HLA-DRB1 is associated with early intrahepatic recurrence of hepatocellular carcinoma
15683420 Observational study of gene-disease association. (HuGE Navigator)
15666025 Observational study of genotype prevalence. (HuGE Navigator)
15665016 Observational study of gene-disease association. (HuGE Navigator)
15665016 ovarian endometriosis is not associated with particular HLA-DRB1 allele(s)
15664787 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15664787 interaction between genetic influences of the polymorphic human leukocyte antigens (DRB1 and DQB1) and psychological distress on the development of cellular immunity to the novel antigen, keyhole limpet hemocyanin
15663743 Observational study of genetic testing. (HuGE Navigator)
15660729 Observational study of gene-disease association. (HuGE Navigator)
15655774 Observational study of gene-disease association. (HuGE Navigator)
15650879 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15645749 Observational study of gene-disease association. (HuGE Navigator)
15643010 Observational study of gene-disease association. (HuGE Navigator)
15642902 Observational study of gene-disease association. (HuGE Navigator)
15641099 Observational study of gene-disease association. (HuGE Navigator)
15640608 Observational study of gene-disease association. (HuGE Navigator)
15640334 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15640103 Observational study of genotype prevalence. (HuGE Navigator)
15629656 The pocket hierarchy established for HLA-DRbeta1*0401 allele was P1 >> P9 ~ P7 > P6 > P4, whilst a P1 >> P4 > P9 ~ P7>P6 pocket hierarchy was found for HLA-DRbeta1*0101, showing how the relative importance of the pockets distinguishes the two alleles.
15627041 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15626888 Observational study of gene-disease association. (HuGE Navigator)
15625617 Observational study of gene-disease association. (HuGE Navigator)
15621102 Observational study of genotype prevalence. (HuGE Navigator)
15620466 Observational study of genetic testing. (HuGE Navigator)
15613143 Observational study of gene-disease association. (HuGE Navigator)
15603876 Observational study of gene-disease association. (HuGE Navigator)
15603876 HLA-DRB1 and -DQB1 alleles as genetic markers for Vogt-Koyanagi-Harada disease in Mestizo patients in Southern California
15603874 Observational study of gene-disease association. (HuGE Navigator)
15602199 Observational study of gene-disease association. (HuGE Navigator)
15585555 Observational study of gene-disease association. (HuGE Navigator)
15585555 the DRB1*01 genotype may be correlated to a higher risk for adrenocortical neoplasms
15572392 Observational study of gene-disease association. (HuGE Navigator)
15570643 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15570643 HLA-DRB1 polymorphism associated with genetic susceptibility of giant cell arteritis.
15565951 Observational study of gene-disease association. (HuGE Navigator)
15561961 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15556690 Observational study of gene-disease association. (HuGE Navigator)
15556690 DRB1*1101 haplotype was lower in HCV-related hepatocellular carcinoma than in controls, whereas DRB1*1104 was higher in HCV-related non-Hodgkin's lymphoma (NHL).
15555263 Observational study of genotype prevalence. (HuGE Navigator)
15554365 Observational study of gene-disease association. (HuGE Navigator)
15548263 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15546341 Observational study of genotype prevalence. (HuGE Navigator)
15535834 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15533584 Observational study of gene-disease association. (HuGE Navigator)
15531903 Observational study of gene-disease association. (HuGE Navigator)
15530631 Observational study of gene-disease association. (HuGE Navigator)
15529553 Observational study of gene-disease association. (HuGE Navigator)
15529553 polymorphisms may be associated with pathogenesis and increase the risk of coronary artery ectasia
15529363 Observational study of gene-disease association. (HuGE Navigator)
15529361 Observational study of gene-disease association. (HuGE Navigator)
15529352 Meta-analysis of gene-disease association. (HuGE Navigator)
15522921 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15507397 Observational study of gene-disease association. (HuGE Navigator)
15505772 Observational study of gene-disease association. (HuGE Navigator)
15505772 Our data do not confirm in Italian patients the previously reported associations of DRB1*01 and DRB1*16 with post streptococcal reactive arthritis and acute rheumatic fever, respectively.
15496201 Observational study of genotype prevalence. (HuGE Navigator)
15496200 Observational study of gene-disease association. (HuGE Navigator)
15492185 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15479890 Observational study of gene-disease association. (HuGE Navigator)
15476205 Observational study of gene-disease association. (HuGE Navigator)
15476204 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15476187 The distribution of HLA-DRB1, DQB1 allele polymorphism in the Kunming Yi nationality population is distinctive. It is neither like that in the South Han population nor like that in the North Han population.
15476187 Observational study of genotype prevalence. (HuGE Navigator)
15471889 Observational study of gene-disease association. (HuGE Navigator)
15471368 Observational study of gene-disease association. (HuGE Navigator)
15468351 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15462607 Observational study of gene-disease association. (HuGE Navigator)
15457442 Genetic variation in the HLA-DRB1 and LTA-TNF regions is associated with treatment response of early RA to methotrexate or etanercept.
15452304 Observational study of genotype prevalence. (HuGE Navigator)
15449022 Observational study of gene-disease association. (HuGE Navigator)
15448101 Observational study of gene-disease association. (HuGE Navigator)
15388265 Observational study of gene-disease association. (HuGE Navigator)
15388265 the relationship of HLA class II alleles to antibody production against glutamic acid decarboxylase (GADab) and to C-peptide secretion (CP) in diabetic patients
15372502 The difference in risk association with multiple sclerosis of DRB1*1501 versus DRB1*1502 is not due to a lack of myelin epitope presentation by DRB1*1502; other mechanisms involving the DRB1*1501 allele should be explored.
15361135 Observational study of genotype prevalence. (HuGE Navigator)
15361127 Observational study of genotype prevalence. (HuGE Navigator)
15357778 Observational study of gene-disease association. (HuGE Navigator)
15350494 Observational study of genotype prevalence. (HuGE Navigator)
15350494 A study of alleles and haplotypes among Arabs in Bahrain and Lebanon.
15343265 Observational study of gene-disease association. (HuGE Navigator)
15343265 Evidence is provided that that the extended haplotype of HLA-DRB1 is distinct in pauciarticular and polyarticular rheumatoid factor negative juvenile idiopathic arthritis patients.
15338511 the susceptibility gene for juvenile dermatomyositis either is HLA-DRB1*15021 or is present near the HLA-DRB1 locus.
15338498 HLA-DRB1 alleles were associated with development of idiopathic inflammatory myopathy and myositis antibodies in a Japanese population.
15336786 Observational study of genotype prevalence. (HuGE Navigator)
15336779 Observational study of gene-disease association. (HuGE Navigator)
15336778 Observational study of gene-disease association. (HuGE Navigator)
15334474 Observational study of gene-disease association. (HuGE Navigator)
15331395 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15325795 Observational study of gene-disease association. (HuGE Navigator)
15323271 Observational study of gene-disease association. (HuGE Navigator)
15321756 Observational study of genotype prevalence. (HuGE Navigator)
15311520 Observational study of genotype prevalence. (HuGE Navigator)
15310011 Observational study of gene-disease association. (HuGE Navigator)
15307871 Observational study of gene-disease association. (HuGE Navigator)
15305487 Observational study of gene-disease association. (HuGE Navigator)
15305244 Observational study of gene-disease association. (HuGE Navigator)
15305244 HLA-DRB1 alleles associated with susceptibility for developing polymyalgia rheumatica and giant cell arteritis in spanish population.
15305234 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15305234 The DRB1*04 allele is associated with autoimmune thyroiditis. There are genotypic differences regarding the presentation forms with a strong association between DRB1*04 and DQB1*03 and the atrophic form only.
15304015 Two novel HLA-DRB1 alleles, DRB1*1443 and DRB1*1351, were identified using a sequence-based typing protocol
15304014 novel allele, designated as DRB1*1145, differs from DRB1*1123 in one nucleotide at position 199 in exon 2 (A replacing T), leading to one amino acid change from phenylalanine (Phe) to isoleucine (Ile) at codon 67.
15304013 Two new HLA-DRB1 alleles have been found by using high-resolution sequence-based typing. The two sequences have been officially named DRB1*1350 (HWS10001327-AY048687) and DRB1*140502 (HWS10001790-AY129430).
15304012 DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively
15304011 Observational study of gene-disease association. (HuGE Navigator)
15304010 Observational study of genetic testing. (HuGE Navigator)
15301864 Polymorphisms in DRB1*030101 alleles outside of exon 2, i.e., an intron 2 complex dinucleotide repeat and an additional complex repeat approximately 1.8 kb downstream of exon 6, do not significantly differ between Type 1 Diabetes patients and controls.
15300424 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15275783 Observational study of gene-disease association. (HuGE Navigator)
15269854 Observational study of gene-disease association. (HuGE Navigator)
15265024 Observational study of gene-disease association. (HuGE Navigator)
15257408 Observational study of gene-disease association. (HuGE Navigator)
15256088 Observational study of gene-disease association. (HuGE Navigator)
15256073 results confirmed the strong effect of HLA-DQB1 alleles on diabetes risk in Romania, with some characteristics which can contribute to the low incidence of type 1 diabetes in this country
15251317 Observational study of genotype prevalence. (HuGE Navigator)
15250035 Observational study of gene-disease association and genetic testing. (HuGE Navigator)
15248209 Observational study of gene-disease association. (HuGE Navigator)
15248208 Observational study of gene-disease association. (HuGE Navigator)
15245541 Observational study of gene-disease association. (HuGE Navigator)
15245369 Observational study of gene-disease association. (HuGE Navigator)
15243926 Observational study of gene-disease association. (HuGE Navigator)
15243926 identified a strong association between HLA-B*0703 and -DRB1*0301 and the development of severe acute respiratory syndrome
15242955 Observational study of genotype prevalence. (HuGE Navigator)
15239092 Observational study of gene-disease association. (HuGE Navigator)
15237447 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15231205 Observational study of gene-disease association. (HuGE Navigator)
15228652 Observational study of genotype prevalence. (HuGE Navigator)
15228651 Observational study of gene-disease association. (HuGE Navigator)
15227724 Observational study of gene-disease association. (HuGE Navigator)
15219383 Observational study of gene-disease association. (HuGE Navigator)
15219382 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15218339 Observational study of gene-disease association. (HuGE Navigator)
15203870 Observational study of gene-disease association. (HuGE Navigator)
15202948 Observational study of gene-disease association. (HuGE Navigator)
15199166 Observational study of gene-disease association. (HuGE Navigator)
15194331 Observational study of gene-disease association. (HuGE Navigator)
15194331 Presence of microchimerism may be associated with acceptance, tolerance and survival of liver allograft.
15194283 Observational study of genotype prevalence. (HuGE Navigator)
15192840 Observational study of gene-disease association. (HuGE Navigator)
15191952 Observational study of gene-disease association. (HuGE Navigator)
15191530 Observational study of genetic testing. (HuGE Navigator)
15191529 Observational study of gene-disease association. (HuGE Navigator)
15191519 Observational study of gene-disease association. (HuGE Navigator)
15188377 DR1 and DR4 not only bind and present the same CII immunodominant peptide, but also stimulate a highly restricted subset of T cells.
15185301 Observational study of gene-disease association. (HuGE Navigator)
15182324 Observational study of gene-disease association. (HuGE Navigator)
15175852 Observational study of gene-disease association. (HuGE Navigator)
15175643 Observational study of gene-disease association. (HuGE Navigator)
15164528 Observational study of gene-disease association. (HuGE Navigator)
15164528 Crohn disease not associated with HLA-DRB1 in Asian Indians.
15158619 Observational study of gene-disease association. (HuGE Navigator)
15158619 A significant increased frequency HLA-DRB1(*)01 and HLA-DRB1(*)13 was found in Mexican (Mestizos) patients with Behcet's disease when compared to controls.
15158329 HLA-DRB1 gene is the major genetic determinant in HLA class II region for children with type 1 autoimmune hepatitis.
15157381 HLA-DRB1 is a susceptibility gene for narcolepsy.
15144476 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15144462 Observational study of gene-disease association. (HuGE Navigator)
15142265 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15140072 Observational study of gene-disease association. (HuGE Navigator)
15128924 Observational study of gene-disease association. (HuGE Navigator)
15128924 association between microchimerism and maternal compatibility at the class II DRB1 and/or DQB1 HLA loci and with the maternal HLA-DQB1*0301 allele.
15124939 Observational study of gene-disease association. (HuGE Navigator)
15124939 HLA drb1 allele may contribute to the development of temporomandibular joint erosion in patient with various rheumatic diseases.
15122136 Observational study of gene-disease association. (HuGE Navigator)
15121303 Observational study of gene-disease association. (HuGE Navigator)
15120192 Observational study of genotype prevalence. (HuGE Navigator)
15120191 Observational study of gene-disease association. (HuGE Navigator)
15116308 Observational study of gene-disease association. (HuGE Navigator)
15104683 Observational study of gene-disease association. (HuGE Navigator)
15102786 Observational study of gene-disease association. (HuGE Navigator)
15096192 Observational study of gene-disease association. (HuGE Navigator)
15089